RESUMEN
We report a case of malignant mesothelioma of tunica vaginalis in a 65-year-old man. The clinical course was marked by local relapse and distant metastases. Based on a review of the literature, the authors discuss the clinical, epidemiological and therapeutic aspects.
Asunto(s)
Mesotelioma/patología , Neoplasias Testiculares/patología , Anciano , Neoplasias Encefálicas/patología , Neoplasias Encefálicas/secundario , Resultado Fatal , Humanos , Masculino , Mesotelioma/secundario , Recurrencia Local de Neoplasia/patología , Estadificación de NeoplasiasRESUMEN
We report here 2 cases of breast angiosarcoma observed at Centre Val-d' Aurelle of Montpellier over a period of 14 years (1980 to 1994). Based on a review of literature, we analyze the epidemiological, pathological, clinical, diagnostic and treatment aspects of this rare type of breast cancer. The difficulties of histological diagnosis are underlined. Mastectomy is the treatment of reference. Breast angiosarcoma has the worst prognosis of all mammary malignancies, with a mean survival of 24 months. The low histologic grade and an early diagnosis are the most important factors of good prognosis. The benefit of irradiation and chemotherapy as adjuvant therapy remains to be demonstrated.
Asunto(s)
Neoplasias de la Mama/terapia , Hemangiosarcoma/terapia , Mastectomía , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias de la Mama/mortalidad , Neoplasias de la Mama/patología , Quimioterapia Adyuvante , Terapia Combinada , Resultado Fatal , Femenino , Hemangiosarcoma/mortalidad , Hemangiosarcoma/patología , Humanos , Escisión del Ganglio Linfático , Persona de Mediana Edad , Metástasis de la Neoplasia , Estadificación de Neoplasias , Pronóstico , Dosificación RadioterapéuticaRESUMEN
Based upon the literature, we discuss epidemiological, histopathological, clinical and treatment aspects of postirradiation sarcomas. The risk of postirradiation sarcoma is very low and negligible in comparison with the beneficial effect of radiotherapy, and it should not be a major factor influencing treatment decision in patients with cancer. The radical surgical approach of postirradiation sarcoma is the treatment which offers the best chance for cure.
Asunto(s)
Neoplasias Inducidas por Radiación , Sarcoma , Humanos , Neoplasias Inducidas por Radiación/diagnóstico , Neoplasias Inducidas por Radiación/mortalidad , Neoplasias Inducidas por Radiación/radioterapia , Neoplasias Inducidas por Radiación/cirugía , Pronóstico , Radioterapia/efectos adversos , Dosificación Radioterapéutica , Factores de Riesgo , Sarcoma/diagnóstico , Sarcoma/mortalidad , Sarcoma/radioterapia , Sarcoma/cirugía , Análisis de SupervivenciaRESUMEN
This study reports five cases of anorectal melanoma treated at Centre Val d'Aurelle-Paul Lamarque in Montpellier. There follows a discussion based upon the literature of epidemiological, clinical, histopathological and therapeutic aspects. Surgery is the treatment of choice but there is major controversy regarding the best method. The decisive prognostic factor appears to be the stage of the disease rather than the type of treatment. The role of radiotherapy, adjuvant chemotherapy and immunotherapy remains to be evaluated.
Asunto(s)
Neoplasias del Ano/terapia , Melanoma/terapia , Neoplasias del Recto/terapia , Adulto , Anciano , Anciano de 80 o más Años , Antineoplásicos/uso terapéutico , Antineoplásicos Fitogénicos/uso terapéutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias del Ano/diagnóstico , Neoplasias del Ano/cirugía , Quimioterapia Adyuvante , Terapia Combinada , Dacarbazina/uso terapéutico , Femenino , Humanos , Inmunoterapia , Masculino , Melanoma/diagnóstico , Melanoma/cirugía , Persona de Mediana Edad , Metástasis de la Neoplasia , Cuidados Paliativos , Pronóstico , Dosificación Radioterapéutica , Radioterapia Adyuvante , Neoplasias del Recto/diagnóstico , Neoplasias del Recto/cirugía , Vindesina/uso terapéuticoRESUMEN
A case of pineal area tuberculoma revealed by grand mal seizures and deterioration of vision is presented. A surgical biopsy and chemotherapy produced good results. This unusual site of tuberculoma demonstrates the usefulness of a direct approach to pineal area masses. It also confirms the effectivity of chemotherapy for tuberculoma.
