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BACKGROUND: Both intense endurance training and valvular regurgitation place a volume load on the right and left ventricles, potentially leading to dilation, but their effects in combination are not well-known. PURPOSE: The purpose of this case series is to describe the combined volume load of intense endurance athletic training and regurgitant valvular disease as well as the challenging assessment of each component's cardiovascular effect. METHODS: In this article, the clinical course of three elite endurance athletes with congenital valvular disease were reviewed. RESULTS: A swimmer with aortic regurgitation, a cyclist with aortic regurgitation, and a cyclist with pulmonary regurgitation were found to have severe dilation of the associated ventricles despite continuing to train at an elite level without symptoms. CONCLUSIONS: Because of the cumulative effects of endurance training and valvular regurgitation, each athlete manifested ventricular dilation out of proportion to their valvular disease and symptoms. Although the effects of congenital valvular disease and athletic remodeling on ventricular dilation have been thoroughly studied individually, their cumulative effect is not well understood. This complicates the assessment of athletes with valvular regurgitation and underscores the need for athlete-specific recommendations for valve replacement.
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Insuficiencia de la Válvula Aórtica/congénito , Insuficiencia de la Válvula Aórtica/fisiopatología , Educación y Entrenamiento Físico , Resistencia Física/fisiología , Insuficiencia de la Válvula Pulmonar/congénito , Insuficiencia de la Válvula Pulmonar/fisiopatología , Adolescente , Adulto , Ciclismo/fisiología , Humanos , Masculino , Volumen Sistólico , Natación/fisiología , Adulto JovenRESUMEN
This article is a commentary on the role of sports cardiologists in the athletic arena and the beneficial impact they offer sports medicine in the comprehensive care of competitive athletes. The focus is a dialogue on current recommendations for primary prevention of sudden cardiac arrest (SCA), incorporating elements of the preparticipation evaluation and continuing care of athletes with diagnosed heart disease (HD). The feasibility and potential advantages of implementing well-designed preparticipation cardiovascular screening programs and the role of sports cardiologists to educate primary care team physicians on secondary prevention of SCA and proper treatment of underlying HD are discussed.
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Cardiología/tendencias , Muerte Súbita Cardíaca/prevención & control , Atención Primaria de Salud/tendencias , Prevención Primaria , Medicina Deportiva/tendencias , HumanosRESUMEN
This article addresses programmatic cardiovascular screening and evaluation of the elite athlete at the intercollegiate, national team, professional, and Olympic levels. Although much of this content may apply to high-school and recreational sports at large, it is not specifically designed to address athletes participating in all sports activities.
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Atletas , Cardiomiopatía Hipertrófica/diagnóstico , Tamizaje Masivo/tendencias , Cardiomiopatía Hipertrófica/genética , Muerte Súbita Cardíaca/prevención & control , Electrocardiografía , HumanosRESUMEN
To perform at the highest level of international competition, athletes need to maximize rest during long travel, and expeditiously overcome the detrimental effects of "jet lag" (JL). The negative effects of JL may be alleviated by adopting a multimodality approach, including the judicious use of melatonin and other pharmacologic agents to aid re-entrainment and improve sleep characteristics. Strict compliance with anti-doping policy is pivotal before and during competition. There have been several recent updates regarding the use of selected medications, which mandate constant vigilance by sports medicine personnel to both evaluate drug efficacy and judiciously prescribe approved medications. It is critical that medical staff maintain familiarity and awareness on a continual basis to effectively educate athletes and support staff.
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Atletas , Doping en los Deportes/prevención & control , Síndrome Jet Lag/tratamiento farmacológico , Política Organizacional , Rendimiento Atlético , Humanos , Síndrome Jet Lag/fisiopatología , Privación de Sueño/tratamiento farmacológicoRESUMEN
The unique demands of exercise and competition can predispose diabetic athletes to harmful complications. A basic understanding of glucose metabolism during exercise, nutritional adequacy, blood glucose control, medications, and management of on-field complications is important for medical personnel who care for diabetic athletes on a daily basis. Diabetic athletes are best managed by "individualized"" preventive and treatment algorithms that should be developed by a team of medical professionals including the athletic trainer, sports nutritionist, and physician.
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Diabetes Mellitus Tipo 1/terapia , Diabetes Mellitus Tipo 2/terapia , Deportes , Complicaciones de la Diabetes/terapia , Diabetes Mellitus Tipo 1/dietoterapia , Diabetes Mellitus Tipo 1/fisiopatología , Diabetes Mellitus Tipo 2/dietoterapia , Diabetes Mellitus Tipo 2/fisiopatología , Carbohidratos de la Dieta/farmacocinética , Ejercicio Físico/fisiología , Índice Glucémico , Humanos , Sistemas de Infusión de InsulinaRESUMEN
CONTEXT: Phonophoresis is purported to represent a method to apply topical medications through the skin to treat soft tissue injuries and inflammatory conditions. Few data are available to demonstrate the clinical effectiveness of the treatment. OBJECTIVE: To determine the effect of ultrasound on the transcutaneous absorption of dexamethasone when occluded with a dressing. DESIGN: Crossover design. SETTING: University general clinical research center. PATIENTS OR OTHER PARTICIPANTS: Ten healthy subjects (age = 29.2 +/- 8.8 years; height = 170.0 +/- 3.9 cm; mass = 67.5 +/- 18.4 kg). INTERVENTION(S): Two grams of 0.33% dexamethasone cream were applied to a 10-cm (2) area on the anterior forearm. The drug was applied to the skin and occluded with a dressing for 30 minutes before the ultrasound and sham ultrasound treatments. The treatments were applied over the drug and occlusive dressing. Ultrasound treatments were delivered at an intensity of 1.0 W/cm (2) (50% pulsed) at an output frequency of 3 MHz for 5 minutes and compared with sham ultrasound treatments that were delivered at an intensity of 0.0 W/cm (2) (50% pulsed) at an output frequency of 3 MHz for 5 minutes. All subjects received both the ultrasound and sham treatments, and the order in which subjects received the treatments was counterbalanced. MAIN OUTCOME MEASURE(S): Serum samples were drawn before treatment and immediately posttreatment and at 2, 4, 6, 8, and 10 hours posttreatment. Using high-performance liquid chromatography, we analyzed serum to determine dexamethasone concentrations. RESULTS: A 2-way repeated-measures analysis of variance (condition x time) revealed a significant main effect for ultrasound treatment ( P = .047). The rate of appearance and the total concentration of dexamethasone in the serum were greater in subjects after phonophoresis than after sham ultrasound. The sham group had only trace amounts of dexamethasone in the serum, indicating that drug absorption was negligible without the ultrasound energy. The effect size of the phonophoresis condition fell within a 95% confidence interval after the baseline measurement. CONCLUSIONS: We found that a phonophoretic effect occurred with dexamethasone when its application saturated the skin.
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Antiinflamatorios/administración & dosificación , Antiinflamatorios/farmacocinética , Dexametasona/administración & dosificación , Dexametasona/farmacocinética , Apósitos Oclusivos , Fonoforesis , Administración Cutánea , Adulto , Antiinflamatorios/sangre , Estudios Cruzados , Dexametasona/sangre , Relación Dosis-Respuesta a Droga , Femenino , Humanos , Masculino , Absorción Cutánea , Resultado del TratamientoRESUMEN
Methicillin resistant Staphylococcus aureus (MRSA), is a problematic infection which is becoming more common in a variety of athletic related environments. Early recognition, diagnosis, and timely management of infection can help minimize the severity of infection and decrease the rate of transmission. Since most sports physical therapists typically lack adequate knowledge and ability to identify cases of MRSA infection, the pur-pose of this review is to provide a background for associated risk factors, recognition, treatment, and prevention of community associated-MRSA in athletic environments.
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Allergic diseases are common in athletes. As such, sports medicine practitioners will be involved in the management of allergic diseases on a nearly daily basis. Appreciating the wide array of allergic manifestations in this active population is essential to their accurate and efficient treatment. Although the bulk of allergic disease in athletes is mild, some allergic manifestations are far more serious and even potentially life-threatening. Aggressive and thoughtful allergy management should ensure that all athletes can continue to compete safely and at the highest level possible.
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Hipersensibilidad/diagnóstico , Hipersensibilidad/terapia , Medicina Deportiva/métodos , Anafilaxia/diagnóstico , Anafilaxia/terapia , Angioedema/diagnóstico , Angioedema/terapia , Conjuntivitis Alérgica/diagnóstico , Conjuntivitis Alérgica/terapia , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/terapia , Ejercicio Físico/fisiología , Hipersensibilidad a los Alimentos/diagnóstico , Hipersensibilidad a los Alimentos/terapia , Humanos , Hipersensibilidad/inmunología , Inmunoterapia/métodos , Rinitis Alérgica Perenne/diagnóstico , Rinitis Alérgica Perenne/terapia , Rinitis Alérgica Estacional/diagnóstico , Rinitis Alérgica Estacional/terapia , Urticaria/diagnóstico , Urticaria/terapiaRESUMEN
Gastrointestinal (GI) illnesses are common in athletes. Various causes include adverse physiologic adaptations of the gut during exercise; excess ingestion of carbohydrate drinks, alcohol, and anti-inflammatory medications; emotional stressors; exposure to pathogens in closed environments and during travel; trauma; and abdominal wall pressure overload. Unfortunately, evidence-based management of GI illnesses in athletes is limited because most studies have compared various GI illnesses between different sports, rather than comparing athletes to nonathletes. This article reviews the evidence that is available specifically relating to etiology, pathophysiology, clinical presentation, relevant differential diagnoses, acute management, and recommendations for specialist consultation of various GI illnesses in the training-room setting.
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Enfermedades Gastrointestinales/diagnóstico , Enfermedades Gastrointestinales/terapia , Medicina Deportiva/métodos , Dolor Abdominal/diagnóstico , Dolor Abdominal/terapia , Adulto , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/terapia , Diarrea/diagnóstico , Diarrea/fisiopatología , Diarrea/terapia , Dispepsia/diagnóstico , Dispepsia/terapia , Ejercicio Físico/fisiología , Femenino , Reflujo Gastroesofágico/diagnóstico , Reflujo Gastroesofágico/terapia , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/terapia , Tracto Gastrointestinal/fisiología , Tracto Gastrointestinal/fisiopatología , Humanos , Enfermedades Intestinales/diagnóstico , Enfermedades Intestinales/terapia , MasculinoRESUMEN
Clear physiologic adaptations to endurance and resistance training occur in the myocardium. These morphologic changes have been identified primarily by echocardiography. In the evaluation of the symptomatic athlete, imaging is a valuable tool. To differentiate athletic hypertrophy from hypertrophic cardiomyopathy, echocardiography, or MRI may be used, although the latter may be superior in the accurate assessment of wall thickness. Either imaging modality may be used to differentiate athletic dilatation from dilated cardiomyopathy in which systolic dysfunction always accompanies the dilatation. To exclude anomalous coronary arteries, either MRI or CT is a reasonable examination, although the latter requires x-ray exposure and iodinated contrast dye. Chest radiograph continues to be the standard imaging modality for athletic lung disease, whereas fluoroscopy and laryngoscopy are useful for identifying vocal cord dysfunction. Knowledge of the utility of these different imaging modalities is crucial to the practitioner of sports medicine.
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Diagnóstico por Imagen/métodos , Cardiopatías/diagnóstico , Enfermedades Pulmonares/diagnóstico , HumanosRESUMEN
Myotonic muscular dystrophy (DM) is characterized by abnormal skeletal muscle Na channel gating and reduced levels of myotonic dystrophy protein kinase (DMPK). Electrophysiological measurements show that mice deficient in Dmpk have reduced Na currents in muscle. We now find that the Na channel expression level is normal in mouse muscle partially or completely deficient in Dmpk. Reduced current amplitudes are not changed by age or gene dose, and the reduction is not due to changes in macroscopic or microscopic gating kinetics. The mechanism of abnormal membrane excitability in DM may in part be silencing of muscle Na channels due to Dmpk deficiency.