A digital image analysis approach to understand the microscopic and macroscopic phenomena in dissolved air flotation.

Dissolved air flotation (DAF) is an effective method for separating suspended oil and solid particles from wastewater by utilizing small air bubbles. This study aims to investigate the impact of key factors, such as saturating pressure and water flow rate, on the separation of fine oil droplets from a water stream. The macroscopic flow patterns within the cell were analyzed using particle image velocimetry (PIV), while Digital Image Analysis (DIA) was employed to study microscopic phenomena, including oil droplet rising velocity and oil-bubble contact mechanisms. Our findings propose a safe operating window (specifically, water flow rate and saturation pressure) for the effective separation of oil droplets without any oil escaping into the clean water stream. It was found that the oil droplet rising velocity increases with the saturation pressure up to 200 kPa. However, a further increase in the pressure of the air saturating chamber leads to a decrease in oil droplet rising velocity. Additionally, we identified a peak in rising velocity at an oil droplet size of approximately 200 µm. Below this threshold, the rising velocity increases with droplet size, while for droplet sizes exceeding 200 µm, the rising velocity decreases with size. This behavior can be explained by the conflicting effects of droplet size increment according to the Stokes law for the rising velocity of oil droplets. As the droplet size increases, the average density of the bubbles/droplet aggregate rises, reducing the ∆ρ in the Stokes law and subsequently lowering the aggregate rising rate. However, as per the Stokes law, the oil droplet rising velocity increases proportionally to the square of its size.

Evaluation of carcinogenic risk of heavy metals due to consumption of rice in Southwestern Iran.

Pollution by heavy metals is a serious global problem due to its toxicity, abiotic characteristics, abundant sources, and cumulative behavior. On the other hand, considering the importance of rice consumption as an important part of nutrition in Lordegan and Ahvaz cities, this study was conducted to evaluate the carcinogenic risk of heavy metals lead, cadmium, zinc, nickel and in local Champa rice cultivated in these two cities. 16 Champa rice samples were collected from the fields of Lordegan and Ahvaz cities. The elements were read in three replicates by Varian 710-ES atomic emission device. The results showed that the concentration of cadmium and nickel in the cultivated rice in the two studied cities was within the range of the national standard of Iran and the Codex standard. Carcinogenic risk values for lead, cadmium and nickel in Champa Lordegan and Ahvaz rice were within the safe range. Also, the non-carcinogenic risk for these heavy metals in the two studied areas was less than 1 and was in the safe range. Rice pollution in Champa in Ahvaz can be due to the industrial nature of this city, and in Lordegan, it is due to pollution through pesticides, chemical fertilizers, and transportation. Long-term consumption of contaminated rice may endanger the health of residents of these areas. It is recommended to carry out regular and up-to-date monitoring strategies in these two cities to prevent the entry of these toxic heavy metals into the human food chain. Also, more studies are needed to evaluate the complete scenario and make definitive decisions.

The concentration of phthalates in drinking water in Iran: A systematic review and meta-analysis.

PAE and PC polymers, such as BPA, are utilized to make water bottles. Due to the lack of polymer-chemical interaction, PAE can enter drinking bottles during production, wrapping, and keeping. Phthalates can transfer from the bottle to the water depending on keeping conditions (temperature, time, sunlight intensity), pH, and bottle capacity. Since there haven't been previous studies published on the subject, the aim of this meta-analysis and systematic review research is to determine the level of phthalates in drinking water consumed in Iranian cities. Web of Science, Science of Direct, Scopus, and PubMed, databases have been used in this study. Eight studies were selected from 556 initial publications after screening for duplication and irrelevant information. Articles from January 1, 2000, to February 10, 2024, were found in the mentioned databases. Among the types of phthalates, the concentration of DEHP was reported higher than the others Because its concentration has been reported in seven out of eight studies. The highest concentration of DEHP was reported by Mehraie(2.22 µg/l), Zare Jeddi (0.8 µg/l), Yousefi (0.77 µg/l), Abtahi (0.76 µg/l), Zare Jeddi (0.42 µg/l), Abdolahnejad(0.15 µg/l), and Pourzamani (0.08 µg/l). The highest concentration of DEP, DBP, BBP, and PA was reported by Abtahi (0.77 µg/l) and Esteki (2.25 µg/l), Mehraie(0.93 µg/l), and Pourzamani (0.83 µg/l). The results of this study showed that the most important phthalates measured in drinking water include DEP, DEHP, DBP, BBP, and PA. According to the results of the present studies, the most important factor in the increase of phthalates is the storage conditions of drinking water (temperature, sunlight, and the type of pipe or bottle).

Ecological risk assessment of heavy metals in urban dust in Iran: A systematic review and meta-analysis.

Background: Heavy metals in street dust are one of the most important sources of pollutants in urban areas. This urban dust can be caused by industrial activities, traffic, erosion of buildings, and fossil fuels. The aim of this systematic review is to evaluate the ecological risk of heavy metals in the dust of Iran's provinces. Methods: This study was conducted in February 2023 in order to investigate the environmental risks associated with heavy metals associated with dust particles in Iran. The present study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Finally, 9 studies were extracted from the search databases. Results: The ecological risk of heavy metals in the present study was as follows: Cd (258.26؛ CI: 83.53, 433) >Pb (52.58؛ CI: 37.15, 68.02) >Cu (24.44؛ CI: 16.74, 32.14)>Ni (14.75؛ CI: 12.68, 16.82)>As (13.53؛ CI: 10.20, 16.85)>Zn (6.32؛ CI: 3.76, 8.87)>V (3.18؛ CI: 2.65, 3.72)>Cr (2.73؛ CI: 2.19, 3.27)>Co (1.94؛ CI: 1.13, 2.74). The mean ranking of the studied Pb ecological risk is as follows: Shiraz.> Tehran > Ahvaz > Ilam > Abadan > Dezful. Conclusion: The ecological risk potential of Cd in Tehran was also much higher than the standard. Therefore, Tehran was the most polluted city studied in terms of the ecological risk potential of Cd (1611.41؛ CI: 1605.98, 1616.84) and Pb (86.54؛ CI: 71.46, 101.62). The average concentration as well as the ecological risk of Cr, Co, and V metals were lower than the standard. Therefore, controlling the sources of heavy metal emissions (especially lead and cadmium) is highly recommended.

The effect of polycyclic aromatic hydrocarbon biomarkers on cardiovascular diseases.

Polycyclic aromatic hydrocarbon (PAHs) are part of particulate matter (PM), which is produced from incomplete combustion of organic matter. Biomarkers mean biological indicators, molecules that indicate a normal or abnormal process in the body and may be a sign of a condition or disease. Studies show that PAHs increase the risk of cardiovascular diseases through processes such as oxidative stress, inflammation and atherosclerosis. The present study focused on the evaluation of health effects PAHs biomarkers on cardiovascular diseases (CVD). In this narrative study, data were collected from databases such as Scopus, PubMed, Web of science and Google Scholar in the period 1975-2023. After screening, duplicate and irrelevant articles were removed. Finally, 68 articles related to the effect of PAHs on CVD were included in the study. In addition to the articles found through the search in databases, another 18 articles from the references of the selected articles were included. According to the finding in during the biotransformation of PAH, a number of metabolites are made, such as phenols, diols, quinones, and epoxides. Phenolic isomers have the highest percentage and biomarkers used for their detection include 2-OHNAP used to trace naphthalene from heating processed food, 3-OHPHEN used to trace phenanthrene from diesel, 2-OHFLU used to trace fluorene and 1-OHPYR used to trace pyrene from cigarette and hookah smoke. According to the result, increasing blood pressure and heart rate and causing atherosclerosis are the main complications due to exposure to PAH metabolite on cardiovascular system. The most important agents that causes this affects including increased homocysteine, cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), serum biomarkers of C-reactive protein, and triglycerides. Result this study showed that cardiovascular diseases risk is increased by exposure to PAH biomarkers from smoking, car emissions, occupational exposure, and incinerators. Therefore, strict controls should be implemented for sources of PAH production and exposure.

Effects of nano and microplastics on the reproduction system: In vitro and in vivo studies review.

Microplastics (MPs) and nanoplastics (NPs), as their name suggest, are tiny plastic particles. The negative impact of MPs as an emerging pollutant on humans is not hidden from anyone. Recent research on how this pollutant affects the reproductive system and how it enters the blood, placenta, and semen has attracted the attention of scientists. This review study deals with the reproductive toxicity of MPs particles in terrestrial animals, aquatic animals, soil fauna, human cells, and human placenta. In vitro and in vivo animal studies showed that MPs can lead to reduced fertility in men, reduced ovarian capacity, apoptosis of granulosa cells, or even reduced sperm motility. They cause oxidative stress and cell apoptosis and inflammatory effects. The results of these animal studies show that MPs may have similar effects on the human reproductive system. However, not much research has been done on human reproductive toxicity by MPs. Therefore, special attention should be paid to the toxicity of the reproductive system by MPs. The purpose of this comprehensive study is to express the importance of the impact of MPs on the reproductive system. These results provide new insight into the potential dangers of MPs.

Exposure to anesthetic gases in the operating rooms and assessment of non-carcinogenic risk among health care workers.

Health care workers employed operating room in hospital and health centers are unavoidably exposed to inhaling toxic gases, including isoflurane and sevoflurane. Chronic contact with these gases increases the risk of spontaneous abortion, congenital anomalies and cancers. Risk assessment is an important tool in predicting the possible risk to personnel's health. Therefore, this study was conducted with the aim of determining the concentration of isoflurane and sevoflurane gas in the air of the operating room and estimating the non-carcinogenic risk caused by them. In this descriptive-cross-sectional study, according to the occupational method (OSHA 103), 23 samples (isoflurane and sevoflurane) were collected in the air of operating rooms of four selected hospitals in Ahvaz city by using SKC sampling pumps and sorbent tube (Anasorb 747). The samples were determined by used to gas chromatography with a flame ionization detector (GC/FID). Statistical analysis, including the Kruskal-Wallis test, was used to compare the average concentration of anesthetic gases, and the one-sample t-test was used to compare the average with the standard level. In all analyses, the significance level was 0.05, which was performed by SPSS version 22 software. Result of this study showed that the average concentration of isoflurane in private and general hospitals were 23.636 and 17.575 ppm, respectively. Also, the average level of sevoflurane were 1.58 and 7.804 ppm. According to the results the mean amount of anesthetic gases was within the range recommended by Iran's Occupational and Environmental Health Center and the permissible threshold limit provided by ACGIH. In addition, non-cancer risks from occupational exposure to isoflurane and sevoflurane in selected private and general hospitals were acceptable (HQ < 1). Although the results show that overall occupational exposure to anesthetic gases is less than acceptable but long-term exposure to anesthetic gases may endanger the health of operating room staffs. Therefore, it is recommended to implement some technical controls, including regular inspection of ventilation systems, the use of advanced ventilation systems with high cleaning power, continuous control of anesthesia devices in terms of leakage, and periodic training of related staff.

Association of the corona virus (Covid-19) epidemic with environmental risk factors.

The current outbreak of the novel coronavirus SARS-CoV-2 (coronavirus disease 2019; previously 2019-nCoV), epicenter in Hubei Province (Wuhan), People's Republic of China, has spread too many other countries. The transmission of the corona virus occurs when people are in the incubation stage and do not have any symptoms. Therefore, the role of environmental factors such as temperature and wind speed becomes very important. The study of Acute Respiratory Syndrome (SARS) indicates that there is a significant relationship between temperature and virus transmission and three important factors, namely temperature, humidity and wind speed, cause SARS transmission. Daily data on the incidence and mortality of Covid-19 disease were collected from World Health Organization (WHO) website and World Meter website (WMW) for several major cities in Iran and the world. Data were collected from February 2020 to September 2021. Meteorological data including temperature, air pressure, wind speed, dew point and air quality index (AQI) index are extracted from the website of the World Meteorological Organization (WMO), The National Aeronautics and Space Administration (NASA) and the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor. Statistical analysis carried out for significance relationships. The correlation coefficient between the number of infected people in one day and the environmental variables in the countries was different from each other. The relationship between AQI and number of infected was significant in all cities. In Canberra, Madrid and Paris, a significant inverse relationship was observed between the number of infected people in one day and wind speed. There is a significant positive relationship between the number of infected people in a day and the dew point in the cities of Canberra, Wellington and Washington. The relationship between the number of infected people in one day and Pressure was significantly reversed in Madrid and Washington, but positive in Canberra, Brasilia, Paris and Wuhan. There was significant relationship between Dew point and prevalence. Wind speed showed a significant relationship in USA, Madrid and Paris. AQI was strongly associated with the prevalence of covid19. The purpose of this study is to investigate some environmental factors in the transmission of the corona virus.

Relationship between exposure to heavy metals on the increased health risk and carcinogenicity of urinary tract (kidney and bladder).

In today's society, with the continuous development of manufacturing industries and factories related to chemicals, the amount of heavy metals in the inhaled air of humans, water and even food consumption has increased dramatically. The aim of this study was investigation of relationship between exposure to heavy metals on the increased carcinogenicity risk of kidney and bladder. Databases used to for searched were the Springer, Google Scholar, Web of Science, Science Direct (Scopus) and PubMed. At the end after sieve we selected 20 papers. Identify all relevant studies published 2000-2021. The results of this study showed that exposure to heavy metals due to the bio accumulative properties of these metals can cause kidney and bladder abnormalities and provide the basis through various mechanisms for malignant tumors in these organs. Based on result this study, since a limited number of heavy metals including copper, iron, zinc and nickel in very small amounts as micronutrients play a very important role in the function of enzymes and the body cells biological reactions, but exposure to some of them like arsenic, lead, vanadium and mercury will cause irreversible effects on people's health and cause various diseases including cancers of the liver, pancreas, prostate, breast, kidney and bladder. The kidneys, ureter and bladder are the most important organs in the urinary tract on human. According to the result of this study, the duty of this urinary system is to remove toxins, chemicals and heavy metals from the blood, balance electrolytes, excrete excess fluid, produce urine and transfer it to the bladder. This mechanism causes the kidneys and bladder to be highly associated with these toxins and heavy metals, which can lead to various diseases in these two important organs. According to the finding the reducing exposure to heavy metals in various ways can prevent many diseases related to this system and reduce the incidence of kidney and bladder cancers.

Associated health risk assessment due to exposure to BTEX compounds in fuel station workers.

OBJECTIVES: The purpose of this review study was to assess the risk of exposure to BTEX compounds in gas station workers and operators. CONTENT: The main components of BTEX compounds are Benzene, Toluene, Ethyl benzene and Xylene. Petroleum, coal large quantities in crude oil and its products are the most important sources of BTEX compounds. These compounds have both high solubility (found in surface and underground waters) and evaporate quickly. Gas stations are one of the most important sources of emission of these compounds in communities. Workers who work in these places have a lot of exposure to these compounds. Exposure to these dangerous compounds can cause many problems for workers. This study was a narrative review article. According to different databases: PubMed, Web of Science, Springer, Cochran and Science Direct, 451 articles were retrieved. 55 full-text articles entered into the analysis process. Finally, 32 articles were selected in this study. The search was restricted to English-language papers published between 1 February 1995 and 13 August 2022. The results of our study showed that the carcinogenic risk (ILCR) for gas station workers in Bangkok (1.82 ∗ 10-4 - 2.50 ∗ 10-4), Shiraz (6.49∗10-7 - 1.27 ∗ 10-5), Brazil (1.82 ∗ 10-4), Ardabil (390∗10-6 ± 1884 ∗ 10-6) and Johannesburg (3.78 ∗ 10-4) was high. The non-cancer risk for oil industry workers of Dilijan (Iran) who were exposed to toluene was also reported in the range of 10-6∗176. The health of gas station workers is affected by exposure to BTEX and gasoline vapor emissions. According to the result this study, BTEX compounds cause genotoxic changes, chromosomal and genetic abnormalities. SUMMARY AND OUTLOOK: Genotoxicity at high levels in gas station workers can cause cancerous and non-cancerous risks. Improving the production process of diesel fuel and gasoline in refineries, using periodical examinations of workers and operators at gas and fuel stations, using Euro 4 and 5 fuels, and replacing worn out cars can play an important role in reducing the emission of BTEX compounds and thus reducing health risks and carcinogenic.

Hospital wastewater treatment methods and its impact on human health and environments.

The scientific development and economic advances have led to the identification of many pathogenic agents in hospital effluents. Hospital wastewaters are qualitatively similar to municipal wastewaters, with the difference that these wastewaters contain toxic and infectious substances and compounds that can be dangerous for the health of the environment, employees of these centers, and the entire community. Therefore, in the last few years, it has been emphasized that all hospitals and medical and health centers should have a treatment facility for their produced wastewater so that the health of the society and people is not threatened. An issue that is not paid attention to has become one of the environmental problems and concerns of the world today. The present study focused on the investigate hospital wastewater treatment methods and its impact on human health and the environment. In this narrative study, the first literature search was performed with four hundred and twenty-three articles were retrieved based on PubMed, Elsevier, Web of science, Spring, and Google Scholar databases. The results of this study showed that wastewater from hospitals and medical centers can play a significant impress in polluting soil and aquatic environments and spreading infectious diseases. According to the mentioned contents, collection and treatment of hospital wastewater is essential. In addition, if hospital wastewater enters the wastewater collection network without knowing its characteristics or with incomplete treatment and finally enters the municipal wastewater treatment plant. It causes many problems, including disturbing the balance of the biological system of the treatment plant. Purification and disposal of hospital wastewater is considered a vital action based on environmental standards. The results of this study also showed that the treatment methods of this type of hospital wastewater can play a significant role in reducing the spread of diseases caused by hospital wastewater treatment, including infectious diseases. The results of this study can be very useful for politicians, the managers of the Ministry of Energy and Health and the Environmental Organization in choosing the appropriate methods and process to reduce hospital wastewater and increase the efficiency of hospital wastewater treatment plants.

Evaluation of the impact of different disinfectants on new coronavirus and human health.

A new health threat was appeared in 2019 known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease 2019 (COVID-19). The new coronavirus distributed all over the world and caused millions of deaths. One way to incomplete the process of COVID-19 transfer from one person to another is using disinfectants. A narrative review study was done on manuscript published documents about the stability of the virus, different types of disinfectants and the effects of disinfectants on SARS-CoV2 and environment from 2005 to 2022 based on Searched databases included Google Scholar, Springer, PubMed, Web of Science and Science Direct (Scopus). All relevant studies published 2005 until 2022 gathered. According to the databases, 670 articles were retrieved. Thirty studies were screened after review and 30 full-text articles entered into the analysis process. Finally, 14 articles were selected in this study. New coronavirus could survive until 9 days in room temperature; the surviving time decreases if temperature increases. The virus can survive in various plastic, glass, and metal surfaces for hours to days. Disinfectants, such as alcohol, isopropanol, formaldehyde, glutaraldehyde, and ethanol, can kill 70-90% viruses in up to 30 s but should be noted that these disinfectants are recognized by Occupational Safety and Health Administration (OSHA) as a potential carcinogen. According to the different reports, increased duration and level of disinfectant exposure can have negative impacts on human and animal health including upper and lower respiratory tract irritation, inflammation, edema, ulceration, and allergic reactions.

The effect of long-term exposure to toxic air pollutants on the increased risk of malignant brain tumors.

Toxic air pollutants are one of the most agent that have many acute, chronic and non-communicable diseases (NCDs) on human health under long or short-term exposure has been raised from the past to the present. The aim of this study was investigation effect of long-term exposure to toxic air pollutants on the increased risk of malignant brain tumors. Databases used to for searched were the PubMed, Web of Science, Springer and Science Direct (Scopus) and Google Scholar. 71 papers based on abstract and article text filtered. In the end after sieve we selected 7 papers. Identify all relevant studies published 1970-2022. The literature showed that exposure to toxic air pollutants and their respiration can cause disorders in different parts of the brain by transmission through the circulatory system and other mechanisms. Various unpleasant abnormalities are caused by the inhalation of toxic air pollutants in the human body that some of the most common of them include chronic lung disease, coronary heart disease and heart attacks, strokes and brain diseases (Parkinson's, Alzheimer's and multiple Sclerosis), cancers (liver, blood, prostate and brain) and eventually death. According to the finding brain health and proper functioning can be easily disrupted by various genetic or external factors such as air pollution, causing a wide range of abnormalities in the brain and malignant brain tumors. The results of this study showed that reducing the concentration of toxic pollutants in the air, that exposure to them play an increasing role in the development of brain diseases can slow down the process of abnormalities in the brain and will have significant impacts on reducing the number of people affected by them.

The effect of toxic air pollutants on fertility men and women, fetus and birth rate.

Human health is affected by various factors such as air pollutants. Exposure to toxic air pollutants is impaired fertility in men and women. The purpose of this review study was investigation of the effect of toxic air pollutants on fertility and birth rate. Databases used to for searched were the PubMed, Web of Science, Springer and Science Direct (Scopus) and Google Scholar. Identify all relevant studies published 1999-2022. In this study, according to databases five hundred articles were retrieved. 33 studies were screened after review and 19 full-text articles entered into the analysis process. Finally, 11 articles were selected in this study. The literature signs a notable health effects from toxic air pollutants and increase risk of infertility in men and women and having a variety of reproductive system cancers such as prostate, bladder, ovary, kidney and uterus. According to the finding toxic air pollutants can increase the risk infertility in men and women, incidence of cancers of reproductive system and decrease the birth rate. Activities that play an important role in reducing the health effects of toxic air pollutants such as infertility in men and women and reducing the population rate of communities are improving the quality of fuel used in the home, car, industries, changing production processes in large industries, installing catalysts to reduce emissions in cars, use more public transportation, plant trees and increase green space per capita, increase public awareness about various effects of toxic air pollutants and protective measures.

Investigation ways of causes needle sticks injuries, risk factors affecting on health and ways to preventive.

Needle sticks injuries (NSIs) has caused many health concerns, including the widespread infection disease. Needle sticks injuries can have high threaten health human especially, all those who are in contact with health and medical centers. The purpose of this review study was the determination the effects of needle sticks injuries (NSIs) on health care worker and patents. In this a review study of literature studied conducted on international databases included Google Scholar, ISI/WOS (Web of Science), Springer, Scopus, Medline/PubMed. The literature signs a notable undesirable affect from potential needle sticks injuries related to ways to preventive and risks factors among patents and health care worker. The literature was shown needle stick injuries can cause with a variety of ways including needle recapping, non-standard safety boxes, thin gloves, and inadequate personal protective equipment. According to the result this study, needle stick injuries can transfer infectious disease (Human Immunodeficiency viruses [HIV], Hepatitis C virus [HCV]) and increase risk health on health care worker and patients. According to research related to the subject, the ways to prevent reduce needle sticks include personal protective equipment, holding retraining courses for medical staff in the direction to raise awareness can significantly reduce cases of needle sticks injuries. Further research using more sophisticated methodology is warranted.

Socioeconomic correlates of face mask use among pedestrians during the COVID-19 pandemic: An ecological study.

Background: Many countries have recommended using face masks for the general population in public places to reduce the risk of COVID-19 transmission. This study aimed to assess the effects of socioeconomic status on face mask use among pedestrians during the COVID-19 pandemic. Methods: This cross-sectional study was conducted in Ahvaz, southwest Iran in August 2020. A total of 10,440 pedestrians have been studied from 92 neighborhoods of the city. Three socioeconomic indicators including Land price, Literacy rate, and the Employment rate for each neighborhood were used in this study. Analysis of Covariance and partial correlation coefficients were applied to assess the relationship between prevalence rates of mask usage and SES indicators. Results: The mean ± SD age of the pedestrians was 32.2 ± 15.1 years. Of 10,440 observed participants, 67.9% were male. The overall prevalence of face mask usage was 45.6%. The prevalence of mask usage in older people and women was significantly higher than the others. The three assessed socioeconomic indicators were directly correlated to the prevalence of mask usage at individual and neighborhood levels. Conclusion: We found that literacy had the strongest correlation with the prevalence of mask usage compared to the land price and employment rate among the three assessed SES indicators. Hence, it can be concluded that the social component of socioeconomic status has a greater effect on mask usage by people than the economic component of socioeconomic status.

Toxic effects due to exposure heavy metals and increased health risk assessment (leukemia).

Heavy metals (HM) are among the elements that are rare in nature and threaten human health, animals, and the environment. Fix sources including (power plants, industries, homes) and mobile sources include (cars and motorcycles) are the main sources production and emission of HM. It is important to understand the main information about sources of emission, chemical processes (reactions, oxidation, and leaching), and how they precipitate. The aim of this study was to evaluation an increased risk of leukemia due to exposure to HM. In this article narrative, the first literature search was performed with 580 articles according to different databases: Elsevier, PubMed, Web of science, Spring, and Google Scholar databases. 70 articles were included in the analysis process. Finally, 8 full-text articles were selected in this research. The search was restricted to English-language papers published between 2000 and 2021. In final stage literature, there is a notable health effect (carcinogenic) because of exposure to heavy metals. According to the results of this research natural procedures and human activities (industrial processes, car exhaust, and cigarette smoke) are the most important of ways that heavy metals can enter the natural cycle. Air, food, soil, water, and groundwater are the main sources of heavy metals that can cause severe disorders in the human body. After entering the body through ingestion heavy metals produce stable bio-toxic compounds. These compounds by disrupting biological processes, interrupt the body's functions and cause various cancers in the human body. The results of this study can help to politicians for make comprehensive decisions to solve the problem and increase public awareness of the use of protective equipment.

Source, toxicity and carcinogenic health risk assessment of heavy metals.

Heavy metals are chemical elements with unique properties that are toxic even in low concentrations and affect human health with different functions. Agricultural and industrial activities, improper disposal of household solid waste and residues related to industrial producers, discharge of household wastewater and agricultural fertilizers are the most important ways in which toxic heavy metals enter the environment, which harms human health and life. A narrative review of the literature was done from 2000 to 2022 based on searched databases included Google Scholar, PubMed, Springer, Web of Science, and Science Direct (Scopus). All relevant studies published 2000 until 2022 gathered. According to the databases, 820 articles were retrieved. 186 and 50 articles were found and selected based on records identified through database searching and additional records identified through other sources. In the next stage, 97 studies were screened after review and 64 full-text articles entered into the analysis process. Finally, 45 articles were selected in this study. Adverse effects of heavy metals on various conditions in the body depend on a number of factors, including dose, route of exposure and chemical species, as well as age, sex, genetics, nutritional status, and duration of exposure to the heavy metal. The existence of significant relationships between long-term and short-term exposure to toxic heavy metals and their adverse effects, including carcinogenicity, has been extensively studied and proven through numerous experiments. However, the mechanisms associated with this complication have not been properly identified, so in future research, there is a great need for comprehensive studies on the carcinogenicity of heavy metals.

Cardiovascular disease, mortality and exposure to particulate matter (PM): a systematic review and meta-analysis.

One of the main factors that causes health effects in humans such as hospital admissions for cardiovascular disease (HACVD), respiratory disease (RD), lung function, cardiovascular mortality (MCVD), lung cancer, and increased mortality is air pollution especially particulate matter (PM). This a systematic review and meta-analysis aims to investigate the effects of particulate matter on the occurrence of cardiovascular disease and mortality. A systematic review and meta-analysis of the literature was done from 2011 to 2021 based on various databases. Based on the result of this study, subgroup analysis based on temperature conditions showed a different estimation in cold cities (6.24, UR (4.36-8.12)), moderate cities (4.86, UR (3.57-6.15)) and warm cities (8.96, UR (7.06-10.86)). Test of group differences showed a significant difference (Q=12.22, p-value<0.001). There was publication bias among the studies (the Egger's test; (Z=14.18, p<0.001)). According result study pooled estimation of AP% for MCVD from the random-effect meta-analysis based on DerSimonian-Laird model, overall is 5.04, UR (3.65-6.43) (Figure 4). Subgroup analysis based on temperature conditions showed the estimation in cold cities (5.47, UR (3.97-6.97)) and moderate cities (4.65, UR (0.54-8.77)). Test of group differences showed a non-significant difference (Q=0.13, p-value=0.71). There was no publication bias among the studies (the Egger's test; (Z=0.82, p=0.376)). Exposed to air pollutants and particulate matter can be increase the risk of cardiovascular disease, respiratory disease, and cardiovascular mortality.

Association of the efficiency of hemodialysis instruments in the removal of microbial and chemical pollutant.

Dialysis water is vital because of various harmful contaminants for patients. The aim of this study was to assess the efficiency of hemodialysis instruments in the removal of microbial and chemical pollutant in educational hospitals affiliated to Ahvaz Jundishapur University of medical sciences, Iran during 2018-2019. This cross-sectional descriptive research studied the microbial and chemical water quality of hemodialysis instruments in Razi, Sina, and Golestan hospitals in Ahwaz, Iran. 72 samples of microbial parameters and 24 samples of chemical parameters were collected from water used in hemodialysis instruments, including microbial characteristics (the total coliform, fecal coliform and heterotrophic bacteria counts) and chemical characteristics (pH, turbidity, PO4, Cl, Mg, So4, Ca, NO2, and EC) at Razi, Imam, and Golestan educational hospitals on all weekdays during 2018-2019. In this study, experiments were done according to the current standard methods, EPA from hemodialysis instruments. Finally, using SPSS18 software and descriptive statistics, the relationship between results at the removal of toxic, microbial, and chemical pollutants in different months and hospitals was investigated. this study showed that the average concentration of chemical characteristics during the warm season at Razi, Imam, and Golestan educational hospitals for pH, Turbidity, PO4, Cl, Mg, So4, Ca, NO2, and EC were (6.867, 6.4475, 6.53); (2.985, 3.035, 1.226); (0.075, 0.245, 0.195); (38.5, 21.965, 144.87); (1.552, 1.657, 39.445); (8.6, 4.5, 21.5), (2.09, 3.187, 78.975); (0.0082, 0.038, 0.155), and (125.25, 70.35, 78.35), respectively during 2018. Also, during 2019, results showed that the average levels of amounts for pH, Turbidity, PO4, Cl, Mg, So4, Ca, NO2, and EC in Razi, Imam, and Golestan educational hospitals were (7.077, 7.252, 6.435), (1.725, 0.595, 4.16), (0.0775, 0.0597, 0.0297), (52.33, 138.81, 20.92), (23.52, 18.227, 8.767), (35, 27.25, 4.05), (14.58, 28.152, 9.25), (0.0067, 0.0045, 0.0032), and (210.52, 121.62, 29.16), respectively. According to the results, hemodialysis instruments in Razi and Imam have a 90% efficiency in removing heterotrophic bacteria counts (HPC). Based on these findings, educational hospital hemodialysis equipment effluent in Ahvaz, Iran was mitted to Iran environmental standards for use in hemodialysis machines. The result showed that the removal percentage level of microbial and chemical pollutants by the hemodialysis process is comparatively suitable. It should be mentioned that in the proper operation and reconstruction, hemodialysis systems can have an increased rate of removal of microbial and chemical pollutants.