Delicious and difficult to resist?: Inhibitory control differs in young women after exposure to food and non-food commercials.

Unhealthy food marketing, a ubiquitous food stimulus, may impact response inhibition, making it more difficult to maintain healthy eating behaviors. Individuals with disordered eating may be particularly susceptible to altered inhibition responses to food stimuli, making them more vulnerable to unhealthy food marketing, which could perpetuate their disordered eating behaviors. The present study examined response inhibition following exposure to food commercials in young women who reported either high levels of disordered eating (HEC) or low/no disordered eating (LEC) (N = 27; age: M = 19.28, SD = 1.01) by measuring event related potentials (ERPs) during a stop-signal task embedded with food stimuli. Results indicated that participants had significantly higher accuracy on stop trials displaying unhealthy food stimuli than trials displaying healthy food stimuli after viewing non-food commercials but displayed no difference after viewing food commercials. LEC individuals displayed a smaller N200/P300 amplitude in response to food stimuli on the stop-signal task after watching food commercials as compared to non-food commercials, but this difference did not exist for HEC individuals. Results indicate that unhealthy food commercials may impact behavioral and electrophysiological correlates of response inhibition evoked by food stimuli in young women, and individuals with disordered eating might actually be less responsive to food marketing than those without disordered eating.

Differential effects of semantic distance, distractor salience, and relations in verbal analogy.

Prior studies of A:B::C:D verbal analogies have identified several factors that affect performance, including the semantic similarity between source and target domains (semantic distance), the semantic association between the C-term and incorrect answers (distracter salience), and the type of relations between word pairs. However, it is unclear how these stimulus properties affect performance when utilized together. To test their interactive effects, we created a verbal analogy stimulus set that factorially crossed these factors and presented participants with an analogical stem (A:B::C:?) with two response choices: an analogically correct (D) and incorrect distracter (D') term. The semantic distance between source and target word pairs was manipulated creating near (BOWL:DISH::SPOON:SILVERWARE) and far (WRENCH:TOOL::SAD:MOOD) analogies. The salience of an incorrect distracter (D') was manipulated using the sematic distance with the C-term creating low (DRAWER) and high (FORK) salience distracters. Causal, compositional, and categorical relations were presented across these conditions. Accuracies were higher for semantically near than far analogies and when distracter salience was low than high. Categorical relations yielded better performance than the causal and compositional relations. Moreover, a three-way interaction demonstrated that the effects of semantic distance and distracter salience had a greater impact on performance for compositional and causal relations than for the categorical ones. We theorize that causal and compositional analogies, given their less semantically constrained responses, require more inhibitory control than more constraining relations (e.g., categorical).

Why do children struggle on analogical reasoning tasks? Considering the role of problem format by measuring visual attention.

Given the importance of analogical reasoning to bootstrapping children's understanding of the world, why is this ability so challenging for children? Two common sources of error have been implicated: 1) children's inability to prioritize relational information during initial problem solving; 2) children's inability to disengage from salient distractors. Here, we use eye tracking to examine children and adults' looking patterns when solving scene analogies, finding that children and adults attended differently to distractors, and that this attention predicted performance. These results provide the most direct evidence to date that feature based distraction is an important way children and adults differ during early analogical reasoning. In contrast to recent work using propositional analogies, we find no differences in children and adults' prioritization of relational information during problem solving, and while there are some differences in general attentional strategies across age groups, neither prioritization of relational information nor attentional strategy predict successful problem solving. Together, our results suggest that analogy problem format should be taken into account when considering developmental factors in children's analogical reasoning.

Neural differences in the temporal cascade of reactive and proactive control for bilinguals and monolinguals.

This study explored differences in sustained top-down attentional control (i.e., proactive control) and spontaneous types of control (i.e., reactive control) in bilingual and monolingual speakers. We modified a Color-Word Stroop task to varying levels of conflict and included switching trials in addition to more "traditional" inhibition Stroop conditions. The task was administered during scalp electroencephalography (EEG) to evaluate the temporal course of cognitive control during trials. The behavioral Stroop effect was observed across the whole sample; however, there were no differences in accuracy or response time between the bilingual and monolingual groups. Event-related potentials (ERPs) were calculated for the N200, N450, and conflict Sustained Potential (SP). On the pure-blocked incongruent trials, the bilingual group displayed reduced signal during interference suppression (N450) and increased later signal, as indexed by the conflict SP. On the mixed-block incongruent trials, both the bilinguals and monolinguals displayed increased later signal at the conflict SP. This suggests that proactive control may be a default mode for bilinguals on tasks requiring inhibition. In the switching trials, that place high demands on the executive control component of shifting, the language groups did not differ. Overall, these results suggest processing differences between bilinguals and monolinguals extend beyond early response inhibition processes. Greater integration of proactive and reactive control may be needed to sort conflicting language environments for bilinguals, which may be transferring to domain-general mechanisms.

The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing.

This review paper provides an integrative account regarding neurophysiological correlates of positive emotions and affect that cumulatively contribute to the scaffolding for happiness and wellbeing in humans and other animals. This paper reviews the associations among neurotransmitters, hormones, brain networks, and cognitive functions in the context of positive emotions and affect. Consideration of lifespan developmental perspectives are incorporated, and we also examine the impact of healthy social relationships and environmental contexts on the modulation of positive emotions and affect. The neurophysiological processes that implement positive emotions are dynamic and modifiable, and meditative practices as well as flow states that change patterns of brain function and ultimately support wellbeing are also discussed. This review is part of "The Human Affectome Project" (http://neuroqualia.org/background.php), and in order to advance a primary aim of the Human Affectome Project, we also reviewed relevant linguistic dimensions and terminology that characterizes positive emotions and wellbeing. These linguistic dimensions are discussed within the context of the neuroscience literature with the overarching goal of generating novel recommendations for advancing neuroscience research on positive emotions and wellbeing.

The influence of stimulus valence on perceptual processing of facial expressions and subsequent response inhibition.

The constant interplay between affective processing and cognitive control supports emotion regulation and appropriate social functioning. Even when affective stimuli are processed implicitly, threat-related stimuli are prioritized in the earliest stages of processing; yet, it remains unclear how implicit attention to affect influences subsequent cognitive control functions. The present study evaluated the influence of affective valence on early perceptual processes and subsequent response inhibition in a context where affective properties of the stimuli (facial expressions) were not critical for performing the task. Participants (N = 32) completed an affective stop-signal task (SST) while their scalp EEGs were recorded. The SST assessed response inhibition while participants implicitly attended to happy and afraid facial expressions that were matched for level of arousal. Behavioral performance was measured via response time and accuracy while physiological response was measured via the P100, N170, and N200/P300 ERP components. Decreased gender discrimination accuracy, delayed P100 latency, and more negative N170 amplitude were observed for afraid faces compared to happy faces, suggesting a shift in processing with respect to face valence. However, differences in stopping accuracy or N200/P300 ERP components during response inhibition were not observed, pointing to top-down cognitive processes likely being recruited to override the early automatic response to prioritize threat-related stimuli. Findings highlight that, in this implicit affective attention task, threat-related stimuli are prioritized early during processing, but implicitly attending to differentially valenced stimuli did not modulate subsequent cognitive control functions.

The time course of semantic and relational processing during verbal analogical reasoning.

Analogy is an important ability that allows humans to discover relationships between information domains that often vary in surface and relational characteristics. Cognitive neuroscience studies of analogy have demonstrated the importance of the prefrontal cortex during relational comparisons, but little is known about how semantic and relational similarity interact throughout its time course. We used scalp electroencephalography (EEG) analyzed with event-related potentials (ERPs) to examine the neural time course of analogical reasoning while 16 participants solved four-term verbal analogies. Semantic similarity was manipulated by increasing the semantic distance between source and target analogs creating semantically near and far analogies. Relational similarity was manipulated by creating relationally valid and invalid analogies. Only valid analogies were impacted by semantic distance such that far analogies were solved slower and less accurately than near analogies. Correctly solving near analogies elicited more positive waveforms at the N400 and during later relational processing. However, valid analogies elicited more positive signals during only later relational processing and not during the N400. These results suggest that semantic information impacts both early semantic and late relational comparison stages, while relational properties exert more influence in later stages of analogical reasoning. The degree of semantic similarity shared between knowledge domains demonstrated a potent effect throughout the time course of analogy that affected not only semantic access, but also the mapping of relational structures.

Individual Differences in Relational Learning and Analogical Reasoning: A Computational Model of Longitudinal Change.

Children's cognitive control and knowledge at school entry predict growth rates in analogical reasoning skill over time; however, the mechanisms by which these factors interact and impact learning are unclear. We propose that inhibitory control (IC) is critical for developing both the relational representations necessary to reason and the ability to use these representations in complex problem solving. We evaluate this hypothesis using computational simulations in a model of analogical thinking, Discovery of Relations by Analogy/Learning and Inference with Schemas and Analogy (DORA/LISA; Doumas et al., 2008). Longitudinal data from children who solved geometric analogy problems repeatedly over 6 months show three distinct learning trajectories though all gained somewhat: analogical reasoners throughout, non-analogical reasoners throughout, and transitional - those who start non-analogical and grew to be analogical. Varying the base level of top-down lateral inhibition in DORA affected the model's ability to learn relational representations, which, in conjunction with inhibition levels used in LISA during reasoning, simulated accuracy rates and error types seen in the three different learning trajectories. These simulations suggest that IC may not only impact reasoning ability but may also shape the ability to acquire relational knowledge given reasoning opportunities.

Cool, callous and in control: superior inhibitory control in frequent players of video games with violent content.

Research on the effects of media violence exposure has shown robust associations among violent media exposure, increased aggressive behavior, and decreased empathy. Preliminary research indicates that frequent players of violent video games may have differences in emotional and cognitive processes compared to infrequent or nonplayers, yet research examining the amount and content of game play and the relation of these factors with affective and cognitive outcomes is limited. The present study measured neural correlates of response inhibition in the context of implicit attention to emotion, and how these factors are related to empathic responding in frequent and infrequent players of video games with graphically violent content. Participants completed a self-report measure of empathy as well as an affective stop-signal task that measured implicit attention to emotion and response inhibition during electroencephalography. Frequent players had lower levels of empathy as well as a reduction in brain activity as indicated by P100 and N200/P300 event related potentials. Reduced P100 amplitude evoked by happy facial expressions was observed in frequent players compared to infrequent players, and this effect was moderated by empathy, such that low levels of empathy further reduced P100 amplitudes for happy facial expressions for frequent players compared to infrequent players. Compared to infrequent players, frequent players had reduced N200/P300 amplitude during response inhibition, indicating less neural resources were recruited to inhibit behavior. Results from the present study illustrate that chronic exposure to violent video games modulates empathy and related neural correlates associated with affect and cognition.

Compensatory processing during rule-based category learning in older adults.

Healthy older adults typically perform worse than younger adults at rule-based category learning, but better than patients with Alzheimer's or Parkinson's disease. To further investigate aging's effect on rule-based category learning, we monitored event-related potentials (ERPs) while younger and neuropsychologically typical older adults performed a visual category-learning task with a rule-based category structure and trial-by-trial feedback. Using these procedures, we previously identified ERPs sensitive to categorization strategy and accuracy in young participants. In addition, previous studies have demonstrated the importance of neural processing in the prefrontal cortex and the medial temporal lobe for this task. In this study, older adults showed lower accuracy and longer response times than younger adults, but there were two distinct subgroups of older adults. One subgroup showed near-chance performance throughout the procedure, never categorizing accurately. The other subgroup reached asymptotic accuracy that was equivalent to that in younger adults, although they categorized more slowly. These two subgroups were further distinguished via ERPs. Consistent with the compensation theory of cognitive aging, older adults who successfully learned showed larger frontal ERPs when compared with younger adults. Recruitment of prefrontal resources may have improved performance while slowing response times. Additionally, correlations of feedback-locked P300 amplitudes with category-learning accuracy differentiated successful younger and older adults. Overall, the results suggest that the ability to adapt one's behavior in response to feedback during learning varies across older individuals, and that the failure of some to adapt their behavior may reflect inadequate engagement of prefrontal cortex.

Dissociation of category-learning systems via brain potentials.

Behavioral, neuropsychological, and neuroimaging evidence has suggested that categories can often be learned via either an explicit rule-based (RB) mechanism critically dependent on medial temporal and prefrontal brain regions, or via an implicit information-integration (II) mechanism relying on the basal ganglia. In this study, participants viewed sine-wave gratings (Gabor patches) that varied on two dimensions and learned to categorize them via trial-by-trial feedback. Two different stimulus distributions were used; one was intended to encourage an explicit RB process and the other an implicit II process. We monitored brain activity with scalp electroencephalography (EEG) while each participant: (1) passively observed stimuli represented of both distributions; (2) categorized stimuli from one distribution, and, 1 week later; (3) categorized stimuli from the other distribution. Categorization accuracy was similar for the two distributions. Subtractions of Event-Related Potentials (ERPs) for correct and incorrect trials were used to identify neural differences in RB and II categorization processes. We identified an occipital brain potential that was differentially modulated by categorization condition accuracy at an early latency (150-250 ms), likely reflecting the degree of holistic processing. A stimulus-locked Late Positive Complex (LPC) associated with explicit memory updating was modulated by accuracy in the RB, but not the II task. Likewise, a feedback-locked P300 ERP associated with expectancy was correlated with performance only in the RB, but not the II condition. These results provide additional evidence for distinct brain mechanisms supporting RB vs. implicit II category learning and use.

Emotionally anesthetized: media violence induces neural changes during emotional face processing.

Media violence exposure causes increased aggression and decreased prosocial behavior, suggesting that media violence desensitizes people to the emotional experience of others. Alterations in emotional face processing following exposure to media violence may result in desensitization to others' emotional states. This study used scalp electroencephalography methods to examine the link between exposure to violence and neural changes associated with emotional face processing. Twenty-five participants were shown a violent or nonviolent film clip and then completed a gender discrimination stop-signal task using emotional faces. Media violence did not affect the early visual P100 component; however, decreased amplitude was observed in the N170 and P200 event-related potentials following the violent film, indicating that exposure to film violence leads to suppression of holistic face processing and implicit emotional processing. Participants who had just seen a violent film showed increased frontal N200/P300 amplitude. These results suggest that media violence exposure may desensitize people to emotional stimuli and thereby require fewer cognitive resources to inhibit behavior.

A neurocomputational system for relational reasoning.

The representation and manipulation of structured relations is central to human reasoning. Recent work in computational modeling and neuroscience has set the stage for developing more detailed neurocomputational models of these abilities. Several key neural findings appear to dovetail with computational constraints derived from a model of analogical processing, 'Learning and Inference with Schemas and Analogies' (LISA). These include evidence that (i) coherent oscillatory activity in the gamma and theta bands enables long-distance communication between the prefrontal cortex and posterior brain regions where information is stored; (ii) neurons in prefrontal cortex can rapidly learn to represent abstract concepts; (iii) a rostral-caudal abstraction gradient exists in the PFC; and (iv) the inferior frontal gyrus exerts inhibitory control over task-irrelevant information.

A computational account of children's analogical reasoning: balancing inhibitory control in working memory and relational representation.

Theories accounting for the development of analogical reasoning tend to emphasize either the centrality of relational knowledge accretion or changes in information processing capability. Simulations in LISA (Hummel & Holyoak, 1997, 2003), a neurally inspired computer model of analogical reasoning, allow us to explore how these factors may collaboratively contribute to the development of analogy in young children. Simulations explain systematic variations in United States and Hong Kong children's performance on analogies between familiar scenes (Richland, Morrison & Holyoak, 2006; Richland, Chang, Morrison & Au, 2010). Specifically, changes in inhibition levels in the model's working-memory system explain the developmental progression in US children's ability to handle increases in relational complexity and distraction from object similarity during analogical reasoning. In contrast, changes in how relations are represented in the model best capture cross-cultural differences in performance between children of the same ages (3-4 years) in the United States and Hong Kong. We use these results and simulations to argue that the development of analogical reasoning in children may best be conceptualized as an equilibrium between knowledge accretion and the maturation of information processing capability.

Young children's analogical reasoning across cultures: similarities and differences.

A cross-cultural comparison between U.S. and Hong Kong preschoolers examined factors responsible for young children's analogical reasoning errors. On a scene analogy task, both groups had adequate prerequisite knowledge of the key relations, were the same age, and showed similar baseline performance, yet Chinese children outperformed U.S. children on more relationally complex problems. Children from both groups were highly susceptible to choosing a perceptual or semantic distractor during reasoning when one was present. Taken together, these similarities and differences suggest that (a) cultural differences can facilitate better knowledge representations by allowing more efficient processing of relationally complex problems and (b) inhibitory control is an important factor in explaining the development of children's analogical reasoning.

Distraction during relational reasoning: the role of prefrontal cortex in interference control.

We compared the reasoning performance of patients with frontal-variant frontotemporal lobar degeneration (FTLD) with that of patients with temporal-variant FTLD and healthy controls. In a picture analogy task with a multiple-choice answer format, frontal-variant FTLD patients performed less accurately than temporal-variant FTLD patients, who in turn performed worse than healthy controls, when semantic and perceptual distractors were present among the answer choices. When the distractor answer choices were eliminated, frontal-variant patients showed relatively greater improvement in performance. Similar patient groups were tested with a relational-pattern reasoning task that included manipulations of one or two relations and both perceptual and semantic extraneous information. Frontal-variant patients showed performance deficits on all tasks relative to the other subject groups, especially when distracted. These results demonstrate that intact prefrontal cortex (PFC) is necessary for controlling interference from perceptual and semantic distractors in order to reason from relational structure.

Role of gamma-band synchronization in priming of form discrimination for multiobject displays.

Previous research has shown that synchronized flicker can facilitate detection of a single Kanizsa square. The present study investigated the role of temporally structured priming in discrimination tasks involving perceptual relations between multiple Kanizsa-type figures. Results indicate that visual information presented as temporally structured flicker in the gamma band can modulate the perception of multiple objects in a subsequent display. For judgments of both relative orientation and relative position of 2 rectangles, response time to identify and discriminate relations between the objects was consistently decreased when the vertices corresponding to distinct Kanizsa-type rectangles were primed asynchronously. Implications are discussed for models of the perception of objects and their interrelations.

Children's development of analogical reasoning: insights from scene analogy problems.

We explored how relational complexity and featural distraction, as varied in scene analogy problems, affect children's analogical reasoning performance. Results with 3- and 4-year-olds, 6- and 7-year-olds, 9- to 11-year-olds, and 13- and 14-year-olds indicate that when children can identify the critical structural relations in a scene analogy problem, development of their ability to reason analogically interacts with both relational complexity and featural distraction. Error patterns suggest that children are more likely to select a distracting object than to make a relational error for problems that present both possibilities. This tendency decreases with age, and older children make fewer errors overall. The results suggest that changes in analogical reasoning with age depend on the interplay among increases in relational knowledge, the capacity to integrate multiple relations, and inhibitory control over featural distraction.