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1.
Scand J Med Sci Sports ; 34(6): e14683, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38898582

RESUMEN

Our previous study showed that daily six maximal eccentric contractions that were performed 5 days a week for 4 weeks increased maximal voluntary isometric (MVC-ISO), concentric (MVC-CON), and eccentric contraction (MVC-ECC) strength of the elbow flexors and muscle thickness of biceps brachii and brachialis (MT) by 8.3 ± 4.9%, 11.1 ± 7.4%, 13.5 ± 11.5%, and 10.6 ± 5.1%, respectively. In the present study, we tested the hypothesis that the muscle strength and MT would still increase when the training intensity was reduced to 2/3 or 1/3 of the peak MVC-ECC torque. Thirty-six healthy young (19-24 years) adults who had not performed resistance training were placed to three groups (n = 12/group): 2/3MVC or 1/3MVC that performed six eccentric contractions with 2/3 or 1/3 MVC-ECC load using a dumbbell 5 days a week for 4 weeks or control group that did not perform any training. Changes in the MVC-ISO, MVC-CON, MVC-ECC torque, and MT before and after the 4-week period were compared among the groups and with the group of the previous study in which six maximal eccentric contractions were performed 5 days a week for 4 weeks (MVC group; n = 12). The control and 1/3MVC groups showed no significant changes in any measures. Significant (p < 0.05) increases in MVC-ISO (10.3 ± 11.4%), MVC-CON (10.9 ± 9.5%), and MVC-ECC (9.3 ± 8.8%) torque and MT (10.1 ± 9.2%) were observed for the 2/3MVC group. These changes were not significantly different from those of the MVC group. These results suggest that the 2/3-intensity eccentric contractions with a dumbbell are as effective as maximal-intensity isokinetic eccentric contractions to induce muscle adaptations.


Asunto(s)
Contracción Isométrica , Fuerza Muscular , Músculo Esquelético , Torque , Humanos , Fuerza Muscular/fisiología , Adulto Joven , Masculino , Músculo Esquelético/fisiología , Femenino , Contracción Isométrica/fisiología , Entrenamiento de Fuerza/métodos , Contracción Muscular/fisiología , Codo/fisiología
2.
J Sports Sci Med ; 23(1): 73-78, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38455448

RESUMEN

Recently, percussive massage (PM) intervention using a handheld percussive massage device, namely a massage gun, has been used as an easy way to perform vibration functions. Additionally, a product has been developed that allows PM intervention and heat application to be performed simultaneously. Thus, this study aimed to compare the acute effects of PM intervention with and without heat application on dorsiflexion (DF) range of motion (ROM), passive stiffness, and muscle strength in the gastrocnemius muscle. Fifteen healthy young men (20.9 ± 0.2 years) participated in this study. We measured the DF ROM, passive torque at DF ROM (an indicator of stretch tolerance), passive stiffness, and maximum voluntary isometric contraction (MVIC) torque of the plantar flexor muscles before and immediately after 120 seconds PM intervention with and without heat application. The results showed that PM intervention with and without heat application significantly increased DF ROM and passive torque at DF ROM and decreased passive stiffness, not MVIC torque. These results suggest that PM intervention increased ROM and decreased passive stiffness regardless of the presence or absence of the heat application.


Asunto(s)
Calor , Músculo Esquelético , Masculino , Humanos , Músculo Esquelético/fisiología , Rango del Movimiento Articular/fisiología , Contracción Isométrica , Masaje
3.
Biol Sport ; 41(2): 139-145, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38524819

RESUMEN

Foam rolling (FR) intervention has recently attracted attention in sports and rehabilitation settings. However, the effects of FR using different rolling durations have not been fully clarified. Thus, this study focused on FR durations and examined the acute and prolonged (i.e., 20-min; 40-min, 60-min) effects of different FR intervention durations on maximal voluntary concentric contractions (MVC-CON), knee flexion range of motion (ROM), pain pressure threshold (PPT), and tissue hardness. The participants were 10 male university students (22.5 ± 1.0 years), and the target muscles were the dominant leg knee extensors. Three sets of 60-seconds FR interventions were performed in the randomized crossover trials in each condition. The three intervention conditions were fast (1 rolling/2 s, 30-repetition × 3 sets, 90 repetitions), medium (1 rolling/6 s, 10-repetition × 3 sets, 30 repetitions), and slow speed (1 rolling/12 s, 5-repetition × 3 sets, 15 repetitions). Before as well as immediately, 20-min, 40-min, and 60-min after the interventions, MVC-CON, ROM PPT, and tissue hardness were measured. The results showed no interaction effect in the acute effect but a main effect of time for all variables (p < 0.05). Also, no interaction was observed in prolonged effect, but main effects of time were observed in knee flexion ROM, PPT, and tissue hardness (p < 0.01) but not for MVC-CON. Post-hoc tests showed significant PPT (p < 0.05) and knee flexion ROM (p < 0.01) increases up to 20- and 60-minutes respectively after all interventions. Tissue hardness was significantly (p < 0.01) decreased up to 60-minutes after all interventions. This study showed that the FR intervention changed ROM, PPT, tissue hardness, and MVC-CON regardless of rolling duration and that the effects persisted up to 20-60 minutes.

4.
Biol Sport ; 41(2): 19-26, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38524825

RESUMEN

Recently, Foam Rolling (FR) and Vibration Foam Rolling (VFR) have attracted attention in sports and rehabilitation fields. Previous studies have shown that FR and VFR acute interventions effectively increase the range of movement (ROM) and decrease tissue hardness. For application to sports and rehabilitation, it is necessary to compare the acute and prolonged effects of short duration FR and VFR. Therefore, this study aimed to compare and investigate the acute and prolonged (15 minutes) effects of short duration (30-s) FR and VFR interventions on knee extensors. The subjects were 14 male university students (22.4 ± 1.0 years old), in which the knee extensors of the dominant leg were tested. In a cross-over trial, 30-s of FR or VFR were performed with 2-s rolling of the anterior thigh (15 rolls). The frequency of VFR was 35 Hz. Measurements included knee flexion ROM, pain pressure threshold (PPT), tissue hardness, and countermovement jump height. The results of this study showed no interaction effects for all variables, but main time effects were observed for knee flexion ROM, PPT, and tissue hardness. Post-hoc tests showed that knee flexion ROM increased up to 10 minutes after the intervention. PPT significantly increased, and tissue hardness significantly decreased up to 15 minutes after intervention. This study showed that 30-s FR and VFR interventions effectively increased ROM, PPT, and decreased tissue hardness. The effects were prolonged up to 10-15 minutes after the intervention. The results of this study show no advantage of VFR over FR with acute short-term interventions.

5.
J Sports Sci ; 42(1): 38-45, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38394030

RESUMEN

The effects obtained from resistance training depend on the exercise range of motion (ROM) performed. We aimed to examine the acute effects of different exercise ROM resistance training on the plantar flexor muscles. Eighteen healthy untrained male adults participated in three conditions: calf raises in 1) partial condition [final (short muscle length) partial ROM], 2) full condition (full ROM), and 3) control condition. The ankle dorsiflexion (DF) ROM, passive torque at DF ROM, passive stiffness of muscle-tendon unit, and maximal voluntary isometric contraction (MVC-ISO) torque were measured before and immediately after the interventions. There were significant increases in DF ROM, passive torque at DF ROM, and a decrease in MVC-ISO, but no significant interaction in passive stiffness. Post hoc test, DF ROM demonstrated moderate magnitude increases in the full condition compared to the partial (p = 0.023, d = 0.74) and control (p = 0.003, d = 0.71) conditions. Passive torque at DF ROM also showed moderate magnitude increases in the full condition compared to the control condition (p = 0.016, d = 0.69). MVC-ISO had a moderate magnitude decrease in the full condition compared to the control condition (p = 0.018, d=-0.53). Resistance training in the full ROM acutely increases joint ROM to a greater extent than final partial ROM, most likely due to stretch tolerance.


Asunto(s)
Músculo Esquelético , Entrenamiento de Fuerza , Adulto , Humanos , Masculino , Músculo Esquelético/fisiología , Tendones/fisiología , Rango del Movimiento Articular/fisiología , Ejercicio Físico/fisiología , Torque
7.
J Sport Rehabil ; 33(1): 27-32, 2024 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-37917973

RESUMEN

CONTEXT: Nordic hamstring strength (NH strength) and single leg bridge test (SLBT) scores are used to predict the risk of hamstring strain injury. Although NH strength and SLBT scores may be related, the relationship between NH strength and SLBT score remains unknown. OBJECTIVES: This study investigated the relationship between NH strength and SLBT scores in university soccer players. DESIGN: Cross-sectional study. SETTING: Research laboratory. PARTICIPANTS: 38 male university soccer players. MAIN OUTCOME MEASURES: NH strength and SLBT scores. INTERVENTIONS: A participant was instructed to lean forward gradually at the slowest possible speed from a kneeling posture with the knee joint flexed 90° for the NH strength measurement. Participants in the SLBT crossed their arms over their chests, pushed down from their heels, and lifted their hips off the ground as many times as they could until they failed. We investigated the relationship between NH strength and SLBT scores in the left and right sides using Spearman rank correlation coefficient. Additionally, we calculated the percentage of left-right asymmetry in NH strength and SLBT scores and investigated the relationship between these variables using Pearson correlation coefficient. RESULTS: There were no significant correlations between NH strength and SLBT scores in the right (rs = .239, P = .16) and left (rs = .311, P = .065) legs. Furthermore, there was no significant relationship between NH strength and SLBT between-limb asymmetry (r = .073, P = .671). CONCLUSIONS: NH strength and SLBT scores could be different indexes, indicating either maximal muscle strength or muscle endurance. Thus, the findings suggested that when assessing risk factors for hamstring strain injury, both NH strength and SLBT scores should be measured.


Asunto(s)
Músculos Isquiosurales , Fútbol , Humanos , Masculino , Fútbol/lesiones , Pierna , Estudios Transversales , Universidades , Músculos Isquiosurales/fisiología , Fuerza Muscular/fisiología
8.
Eur J Appl Physiol ; 124(1): 329-339, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37505230

RESUMEN

PURPOSE: Our previous study showed that one 3-s maximal eccentric contraction a day performed 5 days a week for 4 weeks (5DW) increased maximal voluntary contraction (MVC) strength of the elbow flexors more than 10%. The present study examined whether muscle strength would still increase when the frequency was reduced to 2 days or 3 days per week. METHODS: Twenty-six healthy young adults were recruited in the present study and placed to two groups (n = 13/group) based on the weekly frequency of the one 3-s maximal eccentric contraction for two (2DW) or three days per week (3DW) for 4 weeks. Changes in MVC-isometric, MVC-concentric, MVC-eccentric torque of the elbow flexors, and muscle thickness of biceps brachii and brachialis (MT) before and after the 4-week training were compared between 2DW and 3DW groups, and also compared to the 5DW group in the previous study. RESULTS: The 2DW group showed no significant changes in MVC torque. Significant (P < 0.05) increases in MVC-concentric (2.5 ± 10.4%) and MVC-eccentric (3.9 ± 4.9%) torque were observed for the 3DW group, but the magnitude of the increase was smaller (P < 0.05) than that presented by the 5DW group (12.8 ± 9.6%, 12.2 ± 7.8%). No significant changes in MT were evident for any of the groups. CONCLUSION: These results suggest that at least three days a week are necessary for the one 3-s maximal eccentric contraction to be effective for increasing muscle strength, and more frequent sessions in a week (e.g., 5 days) appear to induce greater increases in muscle strength.


Asunto(s)
Codo , Contracción Isométrica , Adulto Joven , Humanos , Codo/fisiología , Contracción Isométrica/fisiología , Músculo Esquelético/fisiología , Brazo/fisiología , Fuerza Muscular/fisiología , Torque , Contracción Muscular/fisiología
9.
J Sports Sci Med ; 22(4): 681-687, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38045736

RESUMEN

The usefulness of Foam Roller (FR) even without a rolling stimulus (e.g., static compression with or without dynamic joint movements) has been recently demonstrated; however, the different effects of these methods remain unclear. Thus, this study aimed to compare and investigate the effects of such FR intervention methods on knee extensors. The dominant knee extensors of 20 male university students were investigated using the following four conditions: control (CON), FR with rolling (FR_rolling), FR with static compression (FR_SC), and FR with static compression + dynamic movement of the knee joint (FR_DM). FR_SC was intervened to compress the muscle belly of the knee extensors. FR_DM involved knee flexion and extension while maintaining the FR_SC condition. Knee flexion ROM, pain pressure threshold (PPT), tissue hardness, and countermovement jump (CMJ) height were outcome variables; they were compared before and immediately after the intervention. The results of this study showed that knee flexion ROM was significantly (p < 0.01) increased in FR_rolling (d = 0.38), FR_SC (d = 0.28), and FR_DM (d = 0.64). Tissue hardness was significantly (p < 0.01) decreased in FR_rolling (d = -0.55), FR_SC (d = -0.28), and FR_DM (d = -0.42). A main effect of time (p < 0.01) was observed in knee flexion ROM, PPT, and tissue hardness, but no change in CMJ was observed. The results of this study suggested that clinicians and athletes could choose any method they like as a warm-up routine.


Asunto(s)
Articulación de la Rodilla , Rodilla , Humanos , Masculino , Rango del Movimiento Articular/fisiología , Rodilla/fisiología , Articulación de la Rodilla/fisiología , Extremidad Inferior , Músculo Esquelético/fisiología
10.
PLoS One ; 18(12): e0293938, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38100489

RESUMEN

PURPOSE: Nordic hamstring exercise (NHE) and razor hamstring curl (RHC) are usually performed to train hamstring eccentric contraction strength. However, it is unclear whether there are differences in the intensity of the two methods and the amount of loading on each muscle. Therefore, this study was conducted using peak eccentric force and each muscle surface electromyogram (s-EMG) to provide useful information to decide whether NHE or RHC should be prescribed for training and rehabilitation. METHODS: s-EMG electrodes were placed in the medial gastrocnemius, lateral gastrocnemius, biceps femoris, semitendinosus, gluteus maximus, and erector spinae of the dominant leg of the fifteen healthy male university students with exercise habits. Maximum voluntary isometric contractions of 3 seconds were performed on each muscle followed by NHE and RHC in random order. The outcome variables included peak eccentric force and s-EMG of each muscle calculated by means amplitude during the NHE and RHC. RESULTS: Peak eccentric force was significantly higher in RHC than in NHE (p = 0.001, r = 0.73). However, NHE was significantly higher in s-EMG of semitendinosus (p = 0.04, r = -0.52) than RHC. However, there were no significant differences in EMG of the medial gastrocnemius (p = 0.202, r = -0.34), lateral gastrocnemius (p = 0.496, r = 0.18), biceps femoris (p = 0.061, r = -0.48), gluteus maximus (p = 0.112, r = -0.41), erector spinae (p = 0.45, r = 0.20) between NHE and RHC. CONCLUSIONS: For NHE and RHC, the peak eccentric force exerted during the exercise was significantly higher for RHC, and the s-EMG of semitendinosus was significantly higher for NHE.


Asunto(s)
Músculos Isquiosurales , Humanos , Masculino , Electromiografía , Músculos Isquiosurales/fisiología , Ejercicio Físico/fisiología , Contracción Isométrica/fisiología , Músculos Paraespinales , Fuerza Muscular/fisiología
11.
J Sports Sci Med ; 22(3): 389-396, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37711712

RESUMEN

Static stretching (SS), foam rolling (FR), and a combination of both are used as warm-ups for sports and training. However, no reports have compared or examined the warm-up effects of short-term interventions (i.e., 30-s). Therefore, this study was designed to compare and examine the effects of short-term SS, FR, and SS+FR on knee extensors. The dominant knee extensors of 14 male university students (22.0 ± 1.3 years old) were tested. Five conditions were randomized: 60-s SS, 60-s FR, 30-s SS+ 30-s FR, 30-s SS, and 30-s FR to examine differences in intervention method, duration, and combined. The measures were knee flexion range of motion (ROM), pain pressure threshold (PPT), tissue hardness, maximum voluntary contraction-isometric (MVC-ISO), and MVC-concentric (MVC-CON) torques, measured before and after the intervention. Knee flexion ROM (d = 0.40, d = 0.59, d = 0.54, d = 0.59, d = 0.52 respectively) and PPT (d = 0.77, d = 0.60, d = 0.90, d = 0.74, d = 0.52, respectively) were significantly increased (p < 0.01), and tissue hardness (d = -0.79, d = -0.63, d = -0.53, d = -0.59, d = -0.72, respectively) was significantly decreased (p < 0.01) in all conditions. However, MVC-ISO decreased significantly (p < 0.01) in the 60-s SS and 30-s SS conditions but did not affect MVC-CON in all conditions. The results of this study revealed that SS, FR, and SS+FR interventions for a short-term as a warm-up before exercise were effective in increasing ROM, PPT, and decreasing tissue hardness. However, SS intervention with more than 30-s on the knee extensors decreased muscle strength, so short-term FR intervention is recommended when the goal is to increase ROM while maintaining both MVC-ISO and MVC-CON torques. Similarly, a short-term FR intervention after a short-term SS can eliminate the effect of strength impairments.


Asunto(s)
Ejercicios de Estiramiento Muscular , Masculino , Humanos , Adulto Joven , Adulto , Articulación de la Rodilla , Fuerza Muscular , Umbral del Dolor , Rango del Movimiento Articular
12.
Heliyon ; 9(10): e20288, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37767470

RESUMEN

Background: The findings of previous studies support the efficacy of cold water immersion (CWI) with carbon dioxide (CO2) in enhancing muscle blood flow and maintaining aerobic performance efficiency. We hypothesize that the addition of hydrogen gas (H2), known for its antioxidant properties and role in inflammation regulation, to C-CWI can enhance recovery after eccentric exercise. Subjects: and Methods: Thirty-four healthy subjects performed a knee-extensor eccentric exercise. They were randomly allocated into four groups: control, CWI, CO2-rich CWI (C-CWI), and CO2 + H2 gas mixture CWI (CH-CWI). In the three CWI groups, all subjects were immersed in the appropriate bath at 20 °C for 20 min immediately after 60 repetitions of eccentric exercise. Before exercise and after 48 h of recovery, the subjects' maximal voluntary isometric contraction torque (MVC-ISO), maximal voluntary concentric (MVC-CON) contraction torque, countermovement jump (CMJ) height, knee flexion range of motion (ROM), muscle soreness, and muscle thickness were measured. Results: In the CH-CWI group only, the MVC-ISO, CMJ height, and ROM did not decrease significantly post-exercise, whereas all of these decreased in the other three groups. Muscle soreness at palpation, contraction, and stretching significantly increased post-exercise in all groups. Echo intensity and tissue hardness did not increase significantly in the CH-CWI group. Conclusions: CH-CWI stimulated recovery from impairments in MVC-ISO torque, CMJ height, knee-flexion ROM, tissue hardness, and echo intensity. These findings indicate that CH-CWI can promote recovery after eccentric exercise.

13.
Biol Sport ; 40(3): 753-760, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37398969

RESUMEN

Static stretching (SS) and dynamic stretching (DS) in combination with foam rolling (FR) have been attracting attention as warm-up routines in sports. However, the combined and intervention order effects of SS or DS and FR on flexibility, muscle strength, and jump performance are still unclear. Therefore, this study aimed to compare the combined effects of FR and SS or DS with the various intervention orders (i.e., SS + FR, DS + FR, FR + SS, DS + FR) on the function and properties of the knee extensors. Using a crossover, random allocation design, 17 male university students (21.0 ± 1.1 y) performed four conditions combining FR and SS or DS. The measurement included knee flexion range of motion (ROM), pain pressure threshold (PPT), tissue hardness, maximum voluntary isometric contraction (MVC-ISO), maximum voluntary concentric contraction (MVC-CON) torque, and single-leg countermovement jump (CMJ) height of the knee extensors. All interventions significantly (p < 0.01) increased knee flexion ROM (SS + FR: d = 1.29, DS + FR: d = 0.45, FR + SS: d = 0.95, FR + DS: d = 0.49), and significantly (p < 0.01) decreased tissue hardness (SS + FR: d = -1.11, DS + FR: d = -0.86, FR + SS: d = -1.29, DS + FR: d = -0.65). There were no significant changes in MVC-ISO, MVC-CON, and CMJ height in all conditions, but a near significant, small magnitude (p = 0.056, d = -0.31) decrease of MVC-ISO was observed in the FR + SS condition. Our results showed that all the combinations of SS or DS and FR effectively decreased tissue hardness and increased ROM without decreasing muscle strength. Also, effect sizes indicated the largest increase in ROM and decrease in tissue stiffness after SS + FR without decreasing muscle strength and jump performance.

14.
Eur J Appl Physiol ; 123(7): 1553-1565, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36934359

RESUMEN

PURPOSE: Changes in elbow flexion torque and biceps brachii electromyogram (EMG) activity over 30 repetitive maximal voluntary concentric-only (CON-only), eccentric-only (ECC-only), and alternative concentric and eccentric (CON-ECC, 30 concentric + 30 eccentric) contractions were examined to compare their muscle fatigue profiles. METHODS: Fifteen healthy young men performed CON-only, ECC-only and CON-ECC in their maximal effort between 10° and 100° elbow flexion on an isokinetic dynamometer at an angular velocity of 30°/s with a 3-s rest between contractions in a randomised order with ≥ 3 days between conditions. Changes in torque and EMG over the repeated contractions and maximal voluntary isometric contraction (MVC-ISO) torque with EMG before the first contraction and immediately after the last contraction were compared among conditions by two-way repeated measures analysis of variance. RESULTS: The torque decreased (p < 0.01) from the first to 30th contraction in CON-only (- 49.5 ± 11.0%), ECC-only (- 32.2 ± 7.4%), and concentric (- 62.3 ± 8.7%) as well as eccentric phase (- 58.9 ± 9.3%) in CON-ECC (- 46.0 ± 12.3% overall). The magnitude of the decrease in the torque was greater (p < 0.01) for the CON-only than ECC-only, and the concentric than an eccentric phase in the CON-ECC. However, MVC-ISO torque decreased (p < 0.01) similarly after CON-only (- 42.9 ± 13.8%) and ECC-only (- 40.1 ± 9.2%), which was smaller (p < 0.01) than CON-ECC (- 56.8 ± 9.2%). EMG over contractions decreased (p < 0.01) for all conditions similarly from the first to the last contraction (- 28.5 ± 26.8%), and EMG in MVC-ISO also decreased similarly for all conditions (- 24.7 ± 35.8%). CONCLUSION: These results suggest greater fatigue resistance in repetitive maximal eccentric than concentric contractions, but the fatigue assessed by MVC-ISO does not show it.


Asunto(s)
Contracción Muscular , Músculo Esquelético , Masculino , Humanos , Contracción Muscular/fisiología , Músculo Esquelético/fisiología , Fatiga Muscular/fisiología , Contracción Isométrica/fisiología , Brazo/fisiología , Torque
15.
Phys Rev Lett ; 130(10): 106501, 2023 Mar 10.
Artículo en Inglés | MEDLINE | ID: mdl-36962025

RESUMEN

We show that effectively cold metastable states in one-dimensional photodoped Mott insulators described by the extended Hubbard model exhibit spin, charge, and η-spin separation. Their wave functions in the large on-site Coulomb interaction limit can be expressed as |Ψ⟩=|Ψ_{charge}⟩|Ψ_{spin}⟩|Ψ_{η-spin}⟩, which is analogous to the Ogata-Shiba states of the doped Hubbard model in equilibrium. Here, the η-spin represents the type of photo-generated pseudoparticles (doublon or holon). |Ψ_{charge}⟩ is determined by spinless free fermions, |Ψ_{spin}⟩ by the isotropic Heisenberg model in the squeezed spin space, and |Ψ_{η-spin}⟩ by the XXZ model in the squeezed η-spin space. In particular, the metastable η-pairing and charge-density-wave (CDW) states correspond to the gapless and gapful states of the XXZ model. The specific form of the wave function allows us to accurately determine the exponents of correlation functions. The form also suggests that the central charge of the η-pairing state is 3 and that of the CDW phase is 2, which we numerically confirm. Our study provides analytic and intuitive insights into the correlations between active degrees of freedom in photodoped strongly correlated systems.

16.
Mol Biol Cell ; 34(5): ar45, 2023 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-36947171

RESUMEN

Purification is essential before differentiating human induced pluripotent stem cells (hiPSCs) into cells that fully express particular differentiation marker genes. High-quality iPSC clones are typically purified through gene expression profiling or visual inspection of the cell morphology; however, the relationship between the two methods remains unclear. We investigated the relationship between gene expression levels and morphology by analyzing live-cell, phase-contrast images and mRNA profiles collected during the purification process. We employed these data and an unsupervised image feature extraction method to build a model that predicts gene expression levels from morphology. As a benchmark, it was confirmed that the method can predict the gene expression levels from tissue images for cancer genes, performing as well as state-of-the-art methods. We then applied the method to iPSCs and identified two genes that are well predicted from cell morphology. Although strong batch (or possibly donor) effects resulting from the reprogramming process preclude the ability to use the same model to predict across batches, prediction within a reprogramming batch is sufficiently robust to provide a practical approach for estimating expression levels of a few genes and monitoring the purification process.


Asunto(s)
Células Madre Pluripotentes Inducidas , Humanos , Células Madre Pluripotentes Inducidas/metabolismo , Reprogramación Celular , Diferenciación Celular/genética , Perfilación de la Expresión Génica , Expresión Génica
17.
Healthcare (Basel) ; 11(4)2023 Feb 07.
Artículo en Inglés | MEDLINE | ID: mdl-36833008

RESUMEN

Algometers are commonly used to measure the pain-pressure threshold (PPT) in various tissues, such as muscle, tendons, or fascia. However, to date, it is not clear if the repeated application of a PPT assessment can adjust the pain thresholds of the various muscles. Therefore, the purpose of this study was to investigate the repeated application of PPT tests (20 times) in the elbow flexor, knee extensor, and ankle plantar flexor muscles in both sexes. In total, 30 volunteers (15 females, 15 males) were tested for their PPT using an algometer on the respective muscles in random order. We found no significant difference in the PPT between the sexes. Moreover, there was an increase in the PPT in the elbow flexors and knee extensors, starting with the eighth and ninth assessments (out of 20), respectively, compared to the second assessment. Additionally, there was a tendency to change between the first assessment and all the other assessments. In addition, there was no clinically relevant change for the ankle plantar flexor muscles. Consequently, we can recommend that between two and a maximum of seven PPT assessments should be applied so as not to overestimate the PPT. This is important information for further studies, as well as for clinical applications.

18.
J Strength Cond Res ; 37(2): 322-327, 2023 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-35544351

RESUMEN

ABSTRACT: Nakamura, M, Konrad, A, Kasahara, K, Yoshida, R, Murakami, Y, Sato, S, Aizawa, K, Koizumi, R, and Wilke, J. The combined effect of static stretching and foam rolling with or without vibration on the range of motion, muscle performance, and tissue hardness of the knee extensor. J Strength Cond Res 37(2): 322-327, 2023-Although the combination of static stretching (SS) and foam rolling (FR) is frequently used for warm-up in sports, the effect of the intervention order is unclear. This study compared mechanical tissue properties, pain sensitivity, and motor function after SS and FR (with and without vibration) performed in different orders. Our randomized, controlled, crossover experiment included 15 healthy male subjects (22.5 ± 3.3 years) who visited the laboratory 5 times (inactive control condition, FR + SS, FR vibration + SS, SS + FR, and SS + FR vibration ) with an interval of ≥48 hours. In each session, subjects completed three 60-second bouts of FR and SS, targeting the anterior thigh. Pressure pain threshold, tissue hardness, knee flexion range of motion (ROM), maximal voluntary isometric (MVC-ISO), and concentric (MVC-CON) torque, as well as countermovement jump height, were determined before and after the intervention. All interventions significantly ( p < 0.01) increased knee flexion ROM ( d = 0.78, d = 0.87, d = 1.39, and d = 0.87, respectively) while decreasing tissue hardness ( d = -1.25, d = -1.09, d = -1.18, and d = -1.24, respectively). However, MVC-ISO torque was significantly reduced only after FR + SS ( p = 0.05, d = -0.59). Our results suggest that SS should be followed by FR when aiming to increase ROM and reduce tissue hardness without concomitant stretch-induced force deficits (MVC-ISO, MVC-CON, and countermovement jump height). Additionally, adding vibration to FR does not seem to affect the magnitude of changes observed in the examined outcomes.


Asunto(s)
Ejercicios de Estiramiento Muscular , Músculo Esquelético , Humanos , Masculino , Dureza , Músculo Esquelético/fisiología , Rango del Movimiento Articular/fisiología , Vibración , Estudios Cruzados , Adulto Joven , Adulto
19.
J Sports Sci Med ; 21(4): 580-585, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-36523900

RESUMEN

Foam rolling (FR) and vibration foam rolling (VFR) interventions have received attention as pre-exercise warm-ups because they maintain performance and increase range of motion (ROM). However, the immediate and prolonged effects and the comparisons between FR and VFR interventions are unknown. Therefore, this study was designed to compare the effects of FR and VFR interventions on passive properties of knee extensors over time (up to 30 min after interventions). A crossover, random allocation design was used with 14 male college students (22.1 ± 1.0 years old) in the control, FR, and VFR conditions. The knee flexion ROM, pain pressure threshold (PPT), and tissue hardness were measured before and immediately after, 10, 20, and 30 minutes after the intervention. The results showed that knee flexion ROM increased significantly immediately after the intervention in both the FR and VFR conditions and maintained up to 30 minutes after both conditions. PPT increased significantly (p < 0.01) immediately after the FR intervention. In the VFR condition, there was a significant increase in PPT immediately after the intervention (p < 0.01) and 10 minutes after the intervention (p < 0.05). Tissue hardness was significantly decreased (p < 0.01) immediately after and 10 minutes after the FR intervention. However, tissue hardness in the VFR condition was significantly decreased (p < 0.01) up to 30 minutes after the intervention. The results suggest that FR and VFR interventions increase knee flexion ROM, and the effect lasts at least 30 minutes, but the effects on PPT and tissue hardness are maintained a longer time in the VFR condition compared to the FR condition. Therefore, VFR can be recommended as a warm-up before exercise to change the passive properties of knee extensors.


Asunto(s)
Rodilla , Vibración , Humanos , Masculino , Adulto Joven , Adulto , Articulación de la Rodilla , Rango del Movimiento Articular , Extremidad Inferior
20.
Phys Rev Lett ; 129(15): 157401, 2022 Oct 07.
Artículo en Inglés | MEDLINE | ID: mdl-36269969

RESUMEN

We reveal the crucial effect of strong spin-charge coupling on high-harmonic generation (HHG) in Mott insulators. In a system with antiferromagnetic correlations, the HHG signal is drastically enhanced with decreasing temperature, even though the gap increases and the production of charge carriers is suppressed. This anomalous behavior, which has also been observed in recent HHG experiments on Ca_{2}RuO_{4}, originates from a cooperative effect between the spin-charge coupling and the thermal ensemble, as well as the strongly temperature-dependent coherence between charge carriers. We argue that the peculiar temperature dependence of HHG is a generic feature of Mott insulators, which can be controlled via the Coulomb interaction and dimensionality of the system. Our results demonstrate that correlations between different degrees of freedom, which are a characteristic feature of strongly correlated solids, have significant and nontrivial effects on nonlinear optical responses.

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