Soil heavy metals contamination and health risk of an endemic plant in southeast of Damavand Mt., Iran.

Considering the toxicological effects of some heavy metals (HMs) in which directly related to mortality and carcinogenicity in the population by their entrance from plants through livestock grazing, and medical skin cream, the rehabilitation of contaminated sites through phytoremediation by native plants might be quite challenging. Diplotaenia damavandica Mozaff. ex-Hedge & Lamond, is used as medical skin creams due to the existence of specific ingredients, which can be effective in treating skin disease. In the present study, the plant and associated soil sampling were performed around the boundary of D. damavandica. The concentration was measured using the Inductively coupled plasma mass spectrometry (ICP-MS). The results revealed the effect of existing endemic plants on reducing the average concentration of lead and zinc in soil by 40 and 60%, respectively, due to phytoremediation. EDX confirmed the presence of Pb and Zn in root and shoot tissues. Based on the results of this study, D. damavandica is an endemic perennial herbaceous plant with 60% biomass and prosperous root systems, which can grow in low contaminated areas of Pb in the southeast of Damavand Mt. Hence, the HMs pattern indicated less often in the aerial parts except for lead, which should be examined more carefully for skin cream uses.

Dust mitigation by the application of treated sewage effluent (TSE) in Iran.

Considering the presence of 274 dusty days in 2021 in Zabol city, Iran, the present study aimed to evaluate the feasibility of using treated sewage effluent (TSE) for dust mitigation with natural methods of increasing land cover. Hence, first of all, the identification of sewage treatment facilities along with the volume and chemical status was carried out and compared to the various national and international legislation. Then, field investigation on land use and land cover, along with literature review on dust origins, sand detachment areas, and sand corridors in the study area will be assisted for optimal area suggestion. Note that, in the present study it was assumed that the application of TSE for wetting the surface to vegetation restoration resulted in wind erosion control in critical foci. The results showed that, so far, a total of 39,000 m3/day could be treated, in the whole study area. The TSE volume calculated based on two scenarios consisting, (1) data obtained from the related organization, and (2) based the capacity of the wastewater plant is 2.8 and 5.1 mcm/year, respectively. Additionally, the study of TSE quality and its comparison to various regulation such as FAO, USEPA, INS, and CWQI indicated the applicability of transforming TSE to 14 km away from the WWT planet daily for rehabilitation of Hammon Hirmand through irrigation of T.stricta to increase the vegetation cover to above 30%.

Gastroprotective herbs for headache management in Persian medicine: A comprehensive review.

The gut-brain axis is a bidirectional communication system that exists between the brain and gut. Several studies claimed that some types of headaches are associated with various gastrointestinal (GI) disorders. In Persian medicine (PM), physicians believed that gastric disturbances could stimulate headache and introduced some herbs for boosting gastric function as a therapeutic remedy for headache. Here we review the current evidence for the gastroprotective and antiheadache effects of herbs used in PM. Herbs used for their gastrotonic effects in PM were identified from selected Persian medical and pharmaceutical textbooks. PubMed, Scopus and Google Scholar were used to search for contemporary scientific evidence relating to the gastric and neurologic effects of these plants. A total of 24 plants were recorded from the selected sources included in this review, most of which belonged to the Rosaceae family. Phyllanthus emblica, Zingiber officinale, Boswellias errata, Punica granatum and Hypericum perforatum had the most recent studies related to GI disorder and headache, while current research about quince, rose, apple, hawthorn and pear was limited. Reducing Helicobacter pylori growth, gastritis, erosion of the stomach lining, hemorrhage and perforation, improving gastric mucosal resistance, antisecretary, antiulcer, antipyretic, analgesic, sedative, anxiolytic, anti-inflammatory, anticonvulsant, neuroprotective and antioxidant effects as well as improvement in memory scores were some of the gastrotonic and neuroprotective mechanisms described in the current research. These results confirmed that medicinal plants prescribed in PM may improve headache in patients through the management of GI abnormalities. However, further studies are recommended to investigate the efficacy and safety of the mentioned medicinal plants.

Environmental impacts of chemical and microbial grouting.

Climate change is considered the major environmental challenge for the world. Cement and lime production is a highly energy-consuming, heavily polluting process, and the CO2 emissions are very substantial. Alkaline environment, high temperature, and long processing time lead the researchers to work on alternative soil improvements. Microbially induced calcite precipitation (MICP) has been introduced as a technique for modification of geotechnical properties of sand. The main purpose of the present study was to focus on the efficiency and environmental impact of conventional and microbial grouting. Samples were treated with three chemical stabilizers, namely Portland cement, lime, and cement and lime. The stabilizers were injected with flow gravity and constant head which are almost the same as microbial grouting. Then, the results of conventional grouting were compared with the results of biocement samples which were gathered from previous studies to discuss the efficiency and environmental impacts. The results for treated samples were discussed and compared based on 1 m3 of soil and a final target of 700 kPa. It was found that in order to obtain the same compressive strength, the cost and calcium carbonate consumption of the cement injection method were 2.5 times more than those of the microbial method. Biocementation has some advantages over existing technologies, such as less calcium usage in the same unconfined compressive strength (UCS).

Comparison of the efficacy of ranitidine and quince syrup on gastroesophageal reflux disease in children.

INTRODUCTION: Since the treatment of gastroesophageal reflux disease (GERD) symptoms in children is of the utmost importance, the current study is aimed to evaluating the efficacy of quince syrup and ranitidine in the management of pediatric patients with symptomatic GERD. METHODS AND MATERIALS: This double-blind, randomized clinical trial was performed on 96 children suspected of suffering from GERD. The patients referred to the gastrointestinal clinic of Ghaem Hospital, Iran, during 2017. The participants were randomly categorized into two groups (ranitidine and ranitidine plus quince syrup). The GERD symptoms, including the severity and frequency of vomiting, refusal of eating, difficulty in swallowing, choking at the time of eating, burping or belching, and abdominal or belly pain, were gathered before and after the intervention (4 weeks) using standardized Global Severity Questionnaire (GSQ-YC). RESULTS: The comparison of two groups in terms of vomiting, refusal of eating, burping or belching, and abdominal or belly pain showed a significant difference 4 and 6 weeks after the intervention (P< 0.05). However, the comparison of difficulty in swallowing and choking at the time of eating between the two groups showed that there was no significant difference after 2, 4, and 6 weeks of the intervention (P > 0.05). The comparison of the total scores between the two groups showed that there was a significant difference 2 (17.8 ±â€¯2.6 vs 23.4 ±â€¯4.0; P < 0.05), 4 (11.5 ±â€¯2.3 vs 18.8 ±â€¯3.6; P< 0.05), and 6 (12.2 ±â€¯2.3 vs 21.1 ±â€¯4.1; P<  0.05) weeks after the intervention. CONCLUSION: The results showed that the administration of ranitidine plus quince syrup was useful to improve pediatric GERD. However, it is recommended to conduct the future studies with a larger sample size and different dosage.

Saffron (Crocus sativus) in the treatment of gastrointestinal cancers: Current findings and potential mechanisms of action.

Gastrointestinal (GI) cancers are major causes of cancer-related mortality worldwide and include malignancies of the GI tract such as the stomach, liver, pancreas, small intestine, colon, and rectum. Promising and selective anticancer effects of pharmacologically active components of saffron (Crocus sativus L.) have been shown in preclinical in vitro and in vivo studies. Saffron and its active components including crocin, crocetin, and safranal exert their anticancer effects through different mechanisms, including induction of apoptosis, influence on the cell cycle, and regulation of host immune response and anti-inflammatory activities. This review summarizes the recent literature on the chemopreventive properties of saffron in GI cancers to have a better understanding of the potential underlying mechanisms and hence the appropriate management of these malignancies.

Comparison of conventional and bio-treated methods as dust suppressants.

Dust is an environmental, geotechnical, health, and economical hazard. Fugitive dust emanating along transportation systems such as roads, railways, and airports especially can have significant impacts on health, safety, material loss, cost of maintenance, and interfere with the facilities. Quantitative studies on the effectiveness of the proper dust palliatives and their environmental impact have been studied with a number of biological and chemical methods. The objective of this study was to establish a method for using the microbial Induced calcium carbonate precipitation (MICP) approach to reduce the percent of mass loss against erosive force of wind regarding to the concentration and characteristics of aggregate used, climate, and traffic amounts. The results of this study showed that the required precipitation for dust control of sand by 70% is less than 15 g CaCO3/m2 between sand grains in bio-treated sand. The wind tunnel test results of this study also indicate that the effectiveness of the bio-treatment method for dust control depends on many variables, such as the percent of precipitated calcium carbonate and tensile strength.