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1.
JPRAS Open ; 31: 1-9, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34805472

RESUMEN

The incidence of open tibia/fibula fractures in the elderly is increasing, but current national guidelines focus on the aggressive treatment of high-energy injuries in younger patients. There is conflicting evidence regarding whether older age affects treatment provision and outcomes in open fractures. The aim of this study was to determine if elderly patients are sustaining a different injury to younger patients and how their treatment and outcomes differ. This may have implications for future guidelines and verify their application in the elderly. In this retrospective single centre cohort study (December 2015-July 2018), we compared the injury characteristics, operative management and outcomes of elderly (≥65 years) and younger (18-65 years) patients with open tibia/fibula fractures. An extended cohort examined free flap reconstruction. In total, 157 patients were included. High-energy injuries were commoner in younger patients (88% vs 37%; p<0.001). Most were Gustilo-Anderson IIIb in both age groups. Elderly patients waited longer until debridement (21:19 vs 19:00 h) and had longer inpatient stays (23 vs 15 days). There was no difference in time to antibiotics, operative approach or post-operative complications. Despite the low-energy nature of elderly patients' injuries, the severity of soft tissue insult was equivalent to younger patients with high-energy injuries. Our data suggest that age and co-morbidities should not prohibit lower limb reconstruction. The current application of generic guidelines appears suitable in the elderly, particularly in the acute management. We suggest current management pathways and targets be reviewed to reflect the greater need for peri-operative optimisation and rehabilitation in elderly patients.

2.
Spine (Phila Pa 1976) ; 28(7): E143-5, 2003 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-12671370

RESUMEN

STUDY DESIGN: The first case of scoliosis in an Orangutan spine is reported. OBJECTIVES: To study the nature of scoliosis in the spinal specimen, and to determine the etiologic significance to human idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Idiopathic scoliosis has not been observed in primates other than man. Previous studies highlighted the importance of erect posture in the development of idiopathic scoliosis in man. METHODS: A spinal model of an orangutan spine was studied in great detail to determine its nature. The methods used included plain radiographs, computed tomography scans, a three-dimensional plastic model using rapid prototyping, and dissection of the frozen specimen. RESULTS: Features similar to human idiopathic scoliosis were noted including a right-side curve, vertebral rotation to convexity, displacement of the spinal cord to the concavity, and an equal number of ribs on either side. No evidence of congenital anomaly was found. Atypical findings included male gender, a short curve, and kyphosis at the apex. CONCLUSIONS: Although scoliosis found in the orangutan has features similar to idiopathic scoliosis, there also are some dissimilar features, making this diagnosis unlikely. The features observed in this spine suggest that erect posture is important in the morphology of human idiopathic scoliosis.


Asunto(s)
Enfermedades del Simio Antropoideo/patología , Pongo pygmaeus , Escoliosis/veterinaria , Columna Vertebral/diagnóstico por imagen , Columna Vertebral/patología , Animales , Animales de Zoológico , Enfermedades del Simio Antropoideo/diagnóstico por imagen , Encefalitis/veterinaria , Encefalitis/virología , Resultado Fatal , Cifosis/complicaciones , Cifosis/veterinaria , Masculino , Modelos Anatómicos , Infecciones por Retroviridae/sangre , Escoliosis/complicaciones , Spumavirus/aislamiento & purificación , Tomografía Computarizada por Rayos X
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