RESUMEN
Macrophagic activation syndrome (SAM) or Hemophagocytic lymphohistiocytosis is a clinical-biological entity of non-specific proliferation and activation of macrophages of the reticulohistiocytic system, with phagocytosis of the figurative elements of blood. It is a rare pathology combining non-specific clinical and biological signs and images of hemophagocytosis. It can be primary or acquired secondary to an infection, an autoimmune or neoplastic disease. While T or NK lymphomas are the classic causes of reactive SAM and its association with Hodgkin lymphoma is exceptional. This is a diagnostic and therapeutic emergency given the risk of development towards a fatal multivisceral failure due to an absence of appropriate support. This is a report of a case of SAM revealing a case of Hodgkin lymphoma in a 35-year-old patient.
Asunto(s)
Enfermedad de Hodgkin , Linfohistiocitosis Hemofagocítica , Linfoma , Síndrome de Activación Macrofágica , Adulto , Enfermedad de Hodgkin/complicaciones , Enfermedad de Hodgkin/diagnóstico , Humanos , Linfohistiocitosis Hemofagocítica/diagnóstico , Síndrome de Activación Macrofágica/diagnóstico , Síndrome de Activación Macrofágica/etiologíaRESUMEN
Streptococcus intermedius is considered as a commensal of the oropharynx, but can be a source of serious infections. We report a case of cerebral abscess in a young man of 18 years, who was admitted to the emergency room for consciousness disorder, and whose cerebral CT showed a frontal mass evoking the diagnosis of abscess. Diagnosis was confirmed by bacteriological examination of puncture fluid which was in favor of Streptococcus intermedius abscess.