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Clin Geriatr Med
; 38(4): 641-652, 2022 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36210081
RESUMEN
Behavioral and psychological symptoms of dementia (BPSD) may occur in most patients with dementia. Symptoms such as agitation, aggression, and psychosis often lead to higher rates of hospitalization, morbidity, and mortality. Despite the prevalence of BPSD, safe and effective treatment options are limited. This often leads to off-label prescribing and trends toward polypharmacy. Notwithstanding modest efficacy in BPSD, antipsychotics seem to be one of the most commonly prescribed medications in its treatment. Polypharmacy with antipsychotics is particularly troublesome due to the increased risk of potentially lethal adverse effects. As such, their use should be judiciously monitored with the goal of gradual dose reduction.
Asunto(s)
Antipsicóticos , Demencia , Problema de Conducta , Antipsicóticos/uso terapéutico , Síntomas Conductuales/tratamiento farmacológico , Síntomas Conductuales/etiología , Demencia/psicología , Humanos , Polifarmacia
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