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1.
Toxicol Ind Health ; 36(9): 644-653, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-33241766

RESUMEN

Coronavirus disease 2019, otherwise referred to as COVID-19, started in China and quickly became a worldwide pandemic. Beginning in March 2020, nonessential businesses in the United States were closed, and many communities were under shelter-in-place orders. As of May 2020, some business sectors started reopening, even amidst concerns of worker health as the pandemic continued. In addition to physical distancing, cleaning and disinfection routines, and using face coverings, building ventilation can also be an important risk mitigation measure for controlling exposure to SARS-CoV-2 indoors. A number of studies to date, however, have focused on ventilation in medical facilities (e.g. hospitals) as the risk of transmission of SARS-CoV-2 is higher there (because of the close proximity of workers to patients who have the disease and their treatment procedures). Few studies have focused on ventilation use in nonmedical settings (e.g. office buildings and school classrooms), despite the large population of workers and community members in these facilities. In this article, we review the role that building ventilation can play in minimizing the risk of SARS-CoV-2 transmission in nonmedical environments and some recommended protocols to follow for its proper use, including cleaning and maintaining mechanical ventilation systems for businesses, schools, and homes.


Asunto(s)
Contaminación del Aire Interior/prevención & control , COVID-19/prevención & control , Ventilación/métodos , Ventilación/normas , COVID-19/transmisión , Humanos , Pandemias , Lugar de Trabajo
2.
Ann Work Expo Health ; 63(9): 990-1003, 2019 11 13.
Artículo en Inglés | MEDLINE | ID: mdl-31580409

RESUMEN

Hospital technician surgical smoke exposures during several types of electrocautery-based procedures were evaluated. Personal and area air sampling was performed for 106 individual analytes including ultrafine particulate matter (UFP), volatile organic compounds, polycyclic aromatic hydrocarbons, phenol, aldehydes, carbon monoxide, hydrogen sulfide, and hydrogen cyanide. Acetone, d-limonene, ethanol, ethyl acetate, and fluorene were measured in surgical suites at concentrations 1.1- to 3.7-fold higher than those observed in background. Benzene, α-pinene, methylene chloride, and n-hexane were measured in the absence of a detectable background concentration. All analytes were measured at concentrations that were <1% of the corresponding US federal and state 8-h permissible exposure limits (PELs), if PELs existed. Full-shift average UFP concentrations ranged from 773 to 2257 particles/cm3, approximately one order of magnitude higher than surgical suite background concentrations. A comparison of two breast reduction procedures suggested that the use of smoke evacuators reduced UFP exposure by 6-fold. We concluded that selection and evaluation of key hazards, particularly UFP, under a variety of experimental conditions would be beneficial to elucidate potential health effects and causes osf employee complaints. Recommendations for successful sampling campaigns in future surgical smoke occupational exposure studies are provided. We also recommend the continued use of engineering controls, local exhaust ventilation, and surgical N95 respirators to reduce personal exposures to UFP in surgical smoke.


Asunto(s)
Contaminantes Atmosféricos/análisis , Contaminación del Aire Interior/análisis , Electrocoagulación , Exposición Profesional/análisis , Humo/análisis , Humanos , Material Particulado/análisis , Proyectos Piloto , Hidrocarburos Policíclicos Aromáticos/análisis , Ventilación , Compuestos Orgánicos Volátiles/análisis
3.
Data Brief ; 13: 129-131, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28603757

RESUMEN

The data presented in this article are related to the research article entitled "Child and adult exposure and health risk evaluation following the use of metal- and metalloid-containing costume cosmetics sold in the United States" [1]. This article describes the concentration of metals and metalloids contained in various cosmetic products such as body paint, lipstick and eye shadow, the relative percent deviation of two analyses performed on the products and the physico-chemico properties of the metals and metalloids used in the SkinPerm model presented in the aforementioned article.

4.
Regul Toxicol Pharmacol ; 84: 54-63, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28007419

RESUMEN

Costume cosmetics (lipstick, body paints, eyeshadow) were analyzed for metals using inductively coupled plasma mass spectrometry (ICP-MS). Sb was detected in all samples (range: 0.12-6.3 mg/kg; d.f. 100%), followed by Pb (<0.15-9.3 mg/kg), Ni (<0.20-6.3 mg/kg), Co (<0.5-2.0 mg/kg); with d.f. 80% each, Hg (<0.00015-0.0020 mg/kg; d.f. 50%) and As (0.53 mg/kg, d.f. 10%). Ingestion and dermal exposures were estimated for child- and adult-intermittent and adult-occupational users. Adult-occupational users exceeded the U.S. EPA Reference Dose (RfD) for Sb and the CA Proposition 65 maximum allowable dose level (MADL) for Pb was exceeded for all user scenarios. The Pb dose from body paint was sufficient to raise blood lead levels (BLL) in all user scenarios above baseline BLLs from 0.2 µg/dL to 1.9 µg/dL per the Adult Lead Model (ALM) and child Integrated Exposure Uptake Biokinetic (IEUBK) blood Pb models. Change in BLL was less than 1 µg/dL amongst the child and adult-intermittent users, the benchmark change in BLL developed for health risk assessments for children. Adult-occupational users exceeded the CA Proposition 65 NSRL intake value of 15 µg/day, which corresponds to an increase of 1.2 µg/dL above baseline levels using ALM. Exposure of occupational users of costume cosmetics should be evaluated further to prevent unnecessary metal exposure.


Asunto(s)
Cosméticos/análisis , Metaloides/análisis , Metales Pesados/análisis , Administración Cutánea , Adulto , Factores de Edad , Niño , Seguridad de Productos para el Consumidor , Cosméticos/efectos adversos , Relación Dosis-Respuesta a Droga , Intoxicación por Metales Pesados , Humanos , Espectrometría de Masas/métodos , Concentración Máxima Admisible , Metaloides/efectos adversos , Metaloides/sangre , Metales Pesados/efectos adversos , Metales Pesados/sangre , Modelos Biológicos , Enfermedades Profesionales/inducido químicamente , Exposición Profesional/efectos adversos , Ocupaciones , Intoxicación/etiología , Recreación , Medición de Riesgo , Factores de Riesgo , Factores de Tiempo , Estados Unidos
5.
Inhal Toxicol ; 29(12-14): 555-566, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29336178

RESUMEN

Although industrial uses of asbestos have declined since the 1970s, in recent years there has been a renewed interest in para-occupational ("take-home") exposure to these fibers. The aim of this study was to quantify the release of asbestos fibers, if any, during the shaking out of crocidolite- and chrysotile-contaminated clothing in a simulated at-home setting. An exposure study was conducted in which personal and area air samples were collected during the handling (i.e. shake-out) of work clothing (shirt and pants) previously worn by an operator who had cut asbestos-containing cement pipe. During eight "loading" events, the operator cut a historically representative asbestos-containing cement pipe (10% crocidolite and 25% chrysotile) using a powered abrasive saw. Subsequently, 30-minute air samples were collected during four "shake-out" events, each of which consisted of the handling of two complete sets of contaminated work clothes. Samples were analyzed in accordance with NIOSH methods 7400 and 7402. The mean phase contrast microscopy equivalent (PCME) airborne concentrations were 0.52 f/cc (SD = 0.34 f/cc) for total asbestos fibers, 0.36 f/cc (SD = 0.26 f/cc) for chrysotile and 0.17 f/cc (SD = 0.096 f/cc) for crocidolite. Based on likely estimates of the frequency of laundering activities, and assuming that the dusty clothing (1) is not blown off in the occupational setting using compressed air and (2) is not shaken out before entering the home, a family member handling the clothing could potentially have a lifetime cumulative exposure to chrysotile and crocidolite of approximately 0.20 f/cc-year and 0.096 f/cc-year, respectively.


Asunto(s)
Contaminantes Ocupacionales del Aire/análisis , Amianto/análisis , Vestuario , Materiales de Construcción/análisis , Exposición por Inhalación/análisis , Exposición Profesional/análisis , Contaminantes Ocupacionales del Aire/efectos adversos , Amianto/efectos adversos , Vestuario/efectos adversos , Materiales de Construcción/efectos adversos , Humanos , Exposición por Inhalación/efectos adversos , Exposición por Inhalación/prevención & control , Exposición Profesional/efectos adversos , Exposición Profesional/prevención & control
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