RESUMEN
African countries continue to neglect the effects of mental illness on their communities. Identifying barriers to treatment and developing mitigation strategies is essential to address the burden of mental illness within Africa. We searched PubMed, Medline, PSYCHInfo, ERIC, Cochrane Library, ClinicalTrials.gov, and reference lists through June 2020. Studies addressed barriers to mental illness treatment affecting patients and/or their care team. Data was extracted using a standardized data collection form. Three independent, blinded reviewers extrapolated qualitative and quantitative data. Themes were summarized qualitatively. Thirteen studies reflecting urban and rural settings qualified for review. Participants were 17 to 58 years old. Males accounted for 49.9% of the study population. Barriers were categorized as attitudinal, economic, physical, political, and infrastructural. Attitudinal barriers were most prevalent; infrastructural barriers were least discussed. Policy and infrastructural implementations would mitigate interconnected barriers and improve health and wellbeing within Africa. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11469-021-00726-5.