RESUMEN
Both central giant cell granuloma (CGCG) and ossifying fibroma (OF) are relatively common diseases. The synchronous presentation of CGCG and OF is, however, an extremely rare occurrence. We present an unusual case with the synchronous presentation of these two diseases in the maxilla and introduce a surgical strategy based on a combination of the stereolithographic model and navigation system for the treatment of gigantic OF with secondary CGCG.
Asunto(s)
Fibroma Osificante/diagnóstico por imagen , Granuloma de Células Gigantes/diagnóstico por imagen , Neoplasias Maxilares/diagnóstico por imagen , Adulto , Femenino , Fibroma Osificante/complicaciones , Fibroma Osificante/cirugía , Granuloma de Células Gigantes/complicaciones , Granuloma de Células Gigantes/cirugía , Humanos , Enfermedades Maxilares/complicaciones , Enfermedades Maxilares/diagnóstico por imagen , Neoplasias Maxilares/complicaciones , Neoplasias Maxilares/cirugía , Tomografía Computarizada por Tomografía de Emisión de Positrones , Tomografía Computarizada por Rayos XAsunto(s)
Fibroma Osificante/cirugía , Granuloma de Células Gigantes/cirugía , Neoplasias Craneales/cirugía , Adulto , Femenino , Fibroma Osificante/diagnóstico por imagen , Granuloma de Células Gigantes/diagnóstico por imagen , Humanos , Imagenología Tridimensional , Neoplasias Craneales/diagnóstico por imagenRESUMEN
Natural killer (NK)/T-cell lymphomas exhibit aggressive tumor behavior and have a poor prognosis. Recently, self-limited pseudomalignant NK-cell proliferative disorders of the stomach mimicking NK/T-cell lymphomas have been recognized. We report a rare case of lymphomatoid gastropathy in a 71-year-old female. The patient underwent esophagogastroduodenoscopy (EGD) because of slight epigastric discomfort which revealed a 10-mm, reddish, flat elevation with erosion on the posterior wall of the lower gastric body. Histological examination of biopsy specimens showed atypical NK/T cell infiltration with cytoplasmic CD3+, CD4-, CD5-, CD7+, CD8-, CD16-, CD20-, CD56+, CD68-, CD117-, MPO-, TIA1+, and granzyme B+. Epstein-Barr virus-encoded RNA in situ hybridization was negative. Three months later, repeated endoscopic examination surprisingly revealed spontaneous regression of the lesion without any treatment. It is important that endoscopists consider this rare entity in the differential diagnosis, and excessive treatment should be avoided.