RESUMEN
Metastatic Crohn's disease is a rare complication of Crohn's disease that has not been frequently reported in the literature. Although Crohn's disease is common in children, cutaneous manifestations are rarely a presenting sign. We report the case of a young boy who initially presented with unusual skin lesions and whose condition was diagnosed later as Crohn's disease.
Asunto(s)
Enfermedad de Crohn/patología , Enfermedades de la Piel/patología , Enfermedades del Ano/patología , Niño , Granuloma/patología , Humanos , Masculino , Úlceras Bucales/patologíaRESUMEN
Cytomegalovirus (CMV), a member of the herpesviridae family, can cause various dermatologic and systemic disorders especially in immunosuppressed subjects. However, immunocompetent individuals rarely present with cutaneous eruptions related to CMV. We describe an immunocompetent patient who developed a skin eruption and mild hepatitis related to CMV.
Asunto(s)
Infecciones por Citomegalovirus/complicaciones , Inmunocompetencia , Enfermedades Cutáneas Vesiculoampollosas/virología , Enfermedades Cutáneas Virales/complicaciones , Infecciones por Citomegalovirus/inmunología , Femenino , Hepatitis Viral Humana/inmunología , Hepatitis Viral Humana/virología , Humanos , Persona de Mediana Edad , Reacción en Cadena de la Polimerasa/métodos , Enfermedades Cutáneas Vesiculoampollosas/inmunología , Enfermedades Cutáneas Virales/inmunología , Resultado del TratamientoAsunto(s)
Carcinoma Verrugoso/complicaciones , Criptorquidismo/complicaciones , Nevo Pigmentado/complicaciones , Neoplasias Cutáneas/complicaciones , Carcinoma Verrugoso/patología , Niño , Criptorquidismo/patología , Humanos , Inflamación , Masculino , Nevo Pigmentado/patología , Neoplasias Cutáneas/patologíaAsunto(s)
Anticolesterolemiantes/efectos adversos , Erupciones por Medicamentos/etiología , Hipercolesterolemia/tratamiento farmacológico , Simvastatina/efectos adversos , Enfermedades Cutáneas Vesiculoampollosas/inducido químicamente , Enfermedad Aguda , Humanos , Masculino , Persona de Mediana EdadAsunto(s)
Enfermedad de Hodgkin/complicaciones , Prurito/etiología , Prurito/radioterapia , Terapia Ultravioleta/métodos , Femenino , Estudios de Seguimiento , Enfermedad de Hodgkin/diagnóstico , Humanos , Persona de Mediana Edad , Prurito/fisiopatología , Medición de Riesgo , Índice de Severidad de la Enfermedad , Resultado del TratamientoRESUMEN
BACKGROUND: Association of psoriasis vulgaris with HLA antigens reference to age at onset has been reported in different racial or ethnic populations. OBJECTIVE: Our purpose was to determine the distribution of HLA markers in the Turkish population according to the age at onset of the psoriasis vulgaris. METHODS: HLA class I and class II antigens were performed by serologic methods in a group of 100 Turkish patients with psoriasis and 201 control subjects. Patients with psoriasis were subdivided into two groups based on age at onset (below or above 40 years of age) and family history. RESULTS: The frequency of HLA A30, Cw3, Cw6, DR7, DR14, DQ8, and DQ9 antigens were significantly increased in the Turkish psoriatic patients whereas HLA A66, Cw2, Cw4 and DR11 were found to be negatively associated with psoriasis. However, there were striking differences in HLA antigens according to the age at onset of the disease. Type I, early onset was associated with a high frequency of A30, B50, Cw6 and DR7 antigens whereas patients with type II, late onset had an increased frequency of Cw7. CONCLUSIONS: We conclude that psoriasis is probably a genetically determined disease and suggest that HLA-Cw6 antigen seems to associate commonly with early onset of psoriasis in Turkish patients.
Asunto(s)
Edad de Inicio , Predisposición Genética a la Enfermedad/genética , Antígenos de Histocompatibilidad Clase II/genética , Antígenos de Histocompatibilidad Clase I/genética , Psoriasis/genética , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Femenino , Frecuencia de los Genes/genética , Humanos , Región de Control de Posición/genética , Masculino , Persona de Mediana Edad , Oportunidad Relativa , TurquíaRESUMEN
Epidermodysplasia verruciformis (EV) is an autosomal recessive disease characterized by the lifelong eruption of disseminated verrucae-like lesions. Numerous treatment modalities have been used to treat EV without benefit. Recently, retinoid and interferon therapies have been found to be of value in the treatment of EV. We present a case of EV that was treated with a combination of acitretin and interferon alfa-2a.
