1.
Org Lett
; 26(16): 3338-3342, 2024 Apr 26.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38608176
RESUMEN
Isoquinolone is one of the most common heterocyclic core structures in countless natural products and many bioactive compounds. Here, a highly efficient approach to synthesize isoquinolone scaffolds on DNA via rhodium(III)-catalyzed C-H activation has been described. This chemistry transformation is robust and has shown good compatibility with DNA, which is suitable for DNA-encoded library synthesis.