[On the importance of the reflectory-segmental effects for the combined treatment of knee joint osteoporosis in the patients of advanced age].

The present article demonstrates the role of reflectory-segmental effects during baro-laser therapy for the treatment of arthrosis of the knee joints in elderly patients. It has been shown that the additional treatment of the lumbosacral region while applying baro-laser therapy in the patients of the advanced age significantly enhances their functional capabilities including the increase of duration of painless walking and the reduced intensity of the pain syndrome.

Synthesis of some CC chemokines and their receptors in the synovium in rheumatoid arthritis.

We studied the expression of some CC chemokines and their receptors in the synovium of patients with rheumatoid arthritis, osteoarthrosis, and a history of joint injury. In patients with rheumatoid arthritis, the levels mRNA for some angiogenic and proinflammatory chemokines (CCL5/RANTES, CCL11/eotaxin, CCL24/eotaxin-2, and CCL26/eotaxin-3) and their receptors (CCR1, CCR2, CCR3, CCR4, and CCR5) was elevated. mRNA expression correlated with activity, stage, and serological status of rheumatoid arthritis. Obtained data confirm the importance of CC chemokines as mediators of angiogenesis and inflammation in the synovium in rheumatoid arthritis.