Analysis of liver fragment subjected to autologous transplant at rat's retroperitoneum.

BACKGROUND: To investigate the regeneration process of autologous implants of liver on the retroperitoneum. METHODS: Thirty male Fisher rats were used divided in to group 1 (G1): studied 60 d after surgery; group 2 (G2): studied 90 d after surgery; group 3 (G3): studied 180 d after surgery; and group C (GC): animals without surgery. Hepatic fragment was processed for histologic and biochemical analysis. RESULTS: There was inflammatory infiltrate, diffuse hydropic degeneration, necrosis, and moderate fibrosis that reduced in direct relation to the postsurgical time. The concentration of albumin was different between GC and G1 and between G1 and G3 (P = 0.0007). The Catalase (CAT) was related to the time of surgery with GC being different when compared with G1, G2, and G3 (P < 0.0001). The oxidative stress measured through the thiobarbituric acid reactive substances lipid peroxidation was different between the GC and the G2 groups (P = 0.0381). CONCLUSIONS: The analysis made showed hepatic regeneration in the fragment subjected to autologous transplant at the retroperitoneum.

Pseudoaneurisma e CIV pós-IAM concomitantes: apresentação grave e rara / Pseudoaneurysm and VSD concomitant after AMI: severe and rare presentation

Relata-se caso raro de dupla-complicação mecânicapós-IAM anterior: pseudoaneurisma e comunicação interventricular (CIV). Paciente do sexo feminino,66 anos, tendo apresentado quadro de dor torácica típica, foi submetida à cineangiocoronariografia, que demonstrou oclusão total em terço médio de artéria descendente anterior (DA), com angioplastia realizada10 dias após o início do quadro. Evoluiu após três semanas com recidiva de dor precordial, dispneia,sopro sistólico novo, estável hemodinamicamente. Diagnóstico à cineangiocoronariografia e ao ecocardiograma de pseudoaneurisma de parede anterior de ventrículo esquerdo e CIV apical. Realizada correção cirúrgica, com ressecção do aneurisma e correção da CIV, obtendo-se ótimo resultado, apesar da gravidade do caso.

We report a rare case of double mechanical complication after anterior myocardial infarction:pseudoaneurysm and ventricular septal defect (VSD). Female patient, 66 years old, presented with typical chest pain and under went coronary angiography,which showed total occlusion in the middle third ofleft anterior descending artery (DA) with angioplasty performed 10 days after on set of symptoms. Evolved after three weeks with recurrence of chest pain, dyspnea, systolic murmur new, hemodynamically stable. Diagnostic coronary angiography and echocardiography pseudoaneurysm of the anterior wall of the left ventricle and apical VSD. Performed surgical repair with resection of the aneurysm and VSD correction, obtaining excellent results despite the gravity of the case.