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3.
Epidemiol Infect ; 140(10): 1896-903, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22129521

RESUMEN

This study describes the results of the health programme implemented in the Valencian Community (Spain) to achieve an early diagnosis of Chagas disease in pregnant Latin American women and their newborns. During 2009 and 2010, 1975 women living in the health districts of three university hospitals were enrolled via midwives or at the time of delivery. Diagnosis of disease was performed using two serological tests with different antigens. Congenital infection was diagnosed by parasitological, molecular or serological methods from blood samples obtained at birth or in subsequent controls. The overall seroprevalence of Chagas infection in pregnant women from 16 different endemic countries was 11·4%. Infection was higher in those from countries in the Gran Chaco Region (Bolivia, 34·1%; Paraguay, 7·4%; Argentina, 5·3%). Eight newborn infants from Bolivian mothers had congenital Chagas which represents a vertical transmission rate of 3·7%. In conclusion, this work supports the benefits of offering an early diagnosis to pregnant women and newborns during routine prenatal healthcare.


Asunto(s)
Enfermedad de Chagas/congénito , Enfermedad de Chagas/epidemiología , Transmisión Vertical de Enfermedad Infecciosa , Complicaciones Infecciosas del Embarazo/epidemiología , Trypanosoma cruzi/aislamiento & purificación , Adolescente , Adulto , Anticuerpos Antiprotozoarios/sangre , Estudios Transversales , ADN Protozoario/genética , Ensayo de Inmunoadsorción Enzimática , Femenino , Humanos , Recién Nacido , Masculino , Persona de Mediana Edad , Reacción en Cadena de la Polimerasa , Embarazo , Prevalencia , España/epidemiología , Trypanosoma cruzi/genética , Trypanosoma cruzi/inmunología , Adulto Joven
5.
An Esp Pediatr ; 34(1): 68-70, 1991 Jan.
Artículo en Español | MEDLINE | ID: mdl-2018261

RESUMEN

Defects of neural tube closure, although minimal, can provide access for infections of the central nervous system. All skin alterations in rear middle line of the body, however, minimal, must be carefully investigated as they could give access to bacterial meningitis. We present three new cases of dermal lumbosacral sinus which went unnoticed in the neonatal period later becoming the access point for bacterial meningitis.


Asunto(s)
Meningitis/etiología , Defectos del Tubo Neural/complicaciones , Espina Bífida Oculta/complicaciones , Infecciones Bacterianas/etiología , Infecciones Bacterianas/microbiología , Preescolar , Femenino , Humanos , Lactante , Masculino , Meningitis/microbiología , Defectos del Tubo Neural/microbiología , Espina Bífida Oculta/microbiología , Supuración/microbiología , Tomografía Computarizada por Rayos X
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