SLEEP QUALITY OF SCHOOLCHILDREN - RESIDENTS OF RADIOACTIVELY CONTAMINATED AREAS DURING THE COVID-19 PANDEMIC. / ЯКІСТЬ СНУ У ШКОЛЯРІВ ­ МЕШКАНЦІВ РАДІОАКТИВНО ЗАБРУДНЕНИХ ТЕРИТОРІЙ ПІД ЧАС ПАНДЕМІЇ COVID-19.

OBJECTIVE: to assess the sleep characteristics of middle school children during the COVID-19 pandemic. MATERIALS AND METHODS: Cross-sectional study of sleep characteristics of children - residents of radioactively contaminated areas of Zhytomyr and Rivne regions, who underwent a routine examination in June-July 2020, after their stay from March to June 2020 in conditions of home isolation due to quarantine restrictions during the COVID-19 pandemic. Ninety six students of comprehensive public schools, aged 10-16, took part in the study. Sleep characteristics were assessed using the Pittsburgh Sleep Quality Index (PSQI-U indicator), translated into Ukrainian. RESULTS AND DISCUSSION: During the period of the introduction of restrictive measures due to the COVID-19 pandemic, certain disturbances of sleep characteristics were observed, the imprint of which was a moderately increased total PSQI-U indicator, which was (3.89 ± 3.20) points. It was established that 19.79 % of children had insufficient total sleep time, and 2.08 % had significant sleep deprivation. The quality of their sleep was described as «rather bad¼ by 32.29 %, and as «very bad¼ by 4.17 %; 35.42 % of children complained about sleep disturbances, 67.71 % of children had signs of daytime dysfunction, 18.75 % had symptoms of insomnia. In the logistic regression model, quite significant prognostic factors of insomnia were: female gender (OR = 2.487; 95 % CI: 1.407-4.397); subjective determination of the negative impact of the pandemic on health, regardless of whether the respondent had COVID-19 or not (OR = 1.166; 95 % CI: 1.112-1.222), as well as living in the city (OR = 1.183; 95 % CI: 1.065-315). CONCLUSIONS: The introduction of restrictive quarantine measures as a result of the COVID-19 pandemic led to a violation of the daily routine of schoolchildren, which modified the characteristics of sleep. In almost a third of the examined children, the duration and quality of night sleep was insufficient for the physiological restoration of the body's reserves. A late choice of the start of sleep and violations of his hygiene had a critical impact on these indicators.

IDENTIFICATION OF MONOAMINOXIDASE-A GENE PROMOTER POLYMORPHISM (MAOA-UVNTR) AND THEIR RELATIONSHIP WITH AGGRESSIVE BEHAVIOR IN UKRAINIAN CHILDREN. / IDENTYFIKATsIIa POLIMORFIZMU PROMOTORA GENA MONOAMINOKSYDAZY-A (MAOA-UVNTR) TA IOGO ZV'IaZOK Z AGRESYVNOIu POVEDINKOIu V UKRAÏNS'KYKh DITEI.

Aggressive disorders have moderate heritability; therefore, identification of genetic influences is important. TheX-linked MAOA gene encoding the MAOA enzyme has a functional polymorphism of 30 bp repeats. in the promoter region (MAOA-uVNTR), which affects aggression. Stressful life events and family misfortune are also known correlates of behavior disorder in children. OBJECTIVE: to investigate the interactive effect of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) and environmental factors on the development of aggressive behavior. MATERIALS AND METHODS: Genotyping of the MAOA-uVNTR polymorphism was performed in 144 boys and girls aged from 10 to 16 years, genotypes were grouped by a high and low transcriptional activity. For the general assessment of the psycho-emotional sphere of children, the projective method «non-existent animal¼ was used, the indicators and forms of aggression were determined according to the method of A. Bass and A. Darky. RESULTS AND DISCUSSION: It was found the predominant allelic variants of the MAOA gene with 3 (S) and 4 (L) tandem repeats. The presence of close relationships between the dependent variable «aggressive behavior¼ and the predictor variables: «family disadvantage index¼ and «MAOA-uVNTR genotype¼ was established. It has been proven that the presence of the highly active allele (L) in the genotype reduces the chances of developing general aggression, delinquent behavior, physical aggression, open aggression, negativism, and externalization. CONCLUSIONS: The MAOA genotype of the high-activity allele (L) moderated the impact of stressful life events, and the low-activity allele S was associated with increased aggression in girls and boys who experienced severe stress.

ANXIOUSNESS AND QUALITY OF SLEEP IN CHILDREN WHO WERE IN QUARANTINE DURING THE COVID-19 PANDEMIC. / TRYVOZhNIST' TA IaKIST' SNU U DITEI, IaKI PEREBUVALY NA KARANTYNI PID ChAS PANDEMIÏ COVID-19.

OBJECTIVE: to assess the level of anxiety and characterize the quality of sleep in children living in radioactively con-taminated areas in comparison with children who were not affected by the Chornobyl-affected contingents that werequarantined in connection with the COVID-19 pandemic. MATERIALS AND METHODS: The indicators of the level of anxiety were studied using the scale of self-assessment of thelevel of anxiety Ch.D. Spielberger, sleep quality was assessed using a standardized questionnaire for self-completionof PSQI and 137Cs content was measured in children. The main group consisted of 96 children who were quarantineddue to the COVID-19 pandemic and permanently lived in radioactively contaminated areas of Zhytomyr and Rivneregions with a soil contamination density of 137Cs from 18 kBq/m2 to 235 kBq/m2. The age of children ranged from10 to 17 years. Among them were 33 boys and 63 girls. The comparison group consisted of 52 children of similar age,including 26 boys and 26 girls. These children lived permanently in Kyiv and were not victims of the Chornobyl dis-aster. RESULTS: It was found that children who were quarantined for COVID-19 (both residents of radioactively contami-nated areas and children who do not belong to the contingents affected by the Chornobyl disaster) had an increasedlevel of reactive (RA) and personal anxiety (PA). The comparative analysis showed that children of the same sex ofthe main group and the comparison group did not differ in terms of PA and RA. At the same time, studies have shownthat girls, both in the main group and in the comparison group, were characterized by higher levels of PA and RAthan boys. It was determined that poor sleep quality was common in both children living in radioactively contami-nated areas (42.71 %) and children in the comparison group (42.44 %). Among the sleep disorders in children ofboth observation groups, «day dysfunction¼ was most often detected. CONCLUSIONS: There was a direct correlation between the overall PSQI score and the level of reactive, personal anx-iety and the overall PSQI score. Using regression analysis, the presence of a linear association of the level of incorporated 137Cs (Bq) with the indicator of personal anxiety of children living in radioactively contaminated territory (b = -0.716, p < 0.001) was proved.

PSYCHOLOGICAL STATE AND TYPOLOGICAL PERSONALITY FEATURES OF CHILDREN RESIDENTS OF RADIOACTIVELY CONTAMINATED TERRITORIES IN THE REMOTE PERIOD OF CHORNOBYL СATASTROPHE. / PSYKhOLOGIChNYI STAN TA TYPOLOGIChNI RYSY OSOBYSTOSTI DITEI ­ MEShKANTsIV RADIOAKTYVNO ZABRUDNENYKh TERYTORII U VIDDALENYI PERIOD ChORNOBYL'S'KOÏ KATASTROFY.

OBJECTIVE: To evaluate the psycho-emotional state of children-residents of radioactively contaminated territoriesand to characterize the typological features of their personality in the remote period of the Chornobyl catastrophe. MATERIALS AND METHODS: Psycho-emotional status and typological personality traits were determined in 96 childrenaged 12 to 17 years, who resided in radioactively contaminated territories with a soil contamination density of 137Csabove 185 kBq/m-2, and were admitted for examination and treatment in the pediatric departments of the NRCRMclinic. Psycho-emotional state of children was determined using the test «non-existent animal¼, which was assessedin points on symptom complexes: anxiety, aggression and neuro-mental exhaustion. The questionnaire of A. Bassand A. Darkey was used to discriminate various aspects of the aggression symptom complex. In all children, the content of incorporated 137Cs was determined using a whole body counter. RESULTS: The results of the evaluation of the psycho-emotional state of children - residents of radioactively contaminated territories in the remote period of the Chornobyl catastrophe according to the test «non-existent animal¼showed, that the state of anxiety was registered in all 96 children (100 %); state of aggression - in 60 children(62.5 %); exhaustion - in 57 children (59.37 %). Depending on the prevalence of the one or another symptom complexes, or their combination, 5 groups of observations were formed and the personality traits of children characteristic for each group were determined. In the largest group I with the predominance of anxiety symptom complex(45,83 % of the total sample) were noted: stable tendency to perceive many life-threatening situations and environment, pessimistic assessment of one's own life perspective, constant high level of anxiety. Girls were in majorityin this group. For group II, which showed a combination of high rates of two symptom complexes - anxiety andaggression (18.75 % of the total sample), the characteristic personality traits were a constant high level of emotional tension, a tendency to perceive the environment with distrust and a sense of guilt that arouses. In group IIIof children (14.58 % of the total sample), the symptom complex of aggression with feelings of alienation, isolationand hostile attitude towards the environment prevailed. Group IV of children (16.67 % of the total sample), with thecombination of signs of exhaustion and anxiety, had poor ability to concentrate, memory and attention deficit disorders, decreased learning ability, constant fatigue and irritability, apathy, inactivity, and inertia. Group V (only 4.17 %of the total sample) was characterized by low (less than 2 points) indices of all three symptom complexes. Girls weremuch more prone to anxiety, boys were more aggressive, sometimes accompanied by anxiety. Symptom complex ofexhaustion was determined with the same frequency in both boys and girls. CONCLUSION: Assessment of psycho-emotional sphere of children - residents of radioactively contaminated territories in the remote period of the Chornobyl catastrophe according to the «non-existent animal¼ test revealed in of100 % of children the presence of anxiety signs, in the vast majority - the state of aggression and exhaustion. Therewere no probable associations between the content of incorporated 137Cs (in the range from 111 to 7024 Bq) and thepeculiarities of the psycho-emotional state of children.

APPLICATION OF ART THERAPY FOR CORRECTION OF PERSONAL DISORDERS OF PSYCHOEMOTIONAL STATE OF CHILDREN - INHABITANTS OF RADIATION POLLUTED TERRITORIES AND CHILDREN DISPLACED FROM THE ARMED CONFLICT ON THE SOUTHERN EAST OF UKRAINE. / ZASTOSUVANNIa ART-TERAPIÏ DLIa KOREKTsIÏ PORUShEN' PSYKhOEMOTsIY̆NOGO STANU DITEY̆-MEShKANTsIV RADIOAKTYVNO ZABRUDNENYKh TERYTORIY̆ TA DITEY̆, PEREMIShchENYKh IZ ZONY ZBROY̆NOGO KONFLIKTU NA PIVDENNOMU SKhODI UKRAÏNY.

OBJECTIVE: to identify the psycho-emotional state of children - residents of radioactively contaminated territories and children displaced from the zone of armed conflict in the south-east of Ukraine, and evaluate the effectiveness of art therapy application to correct its disturbances. MATERIALS AND METHODS: The psycho-emotional state was determined in 113 children, of which 57 children from radioactively contaminated territories with 137Cs content in the body from 269 Bq to 7024 Bq (group I) and 56 chil- dren displaced from the zone of military conflict in the Southeast of Ukraine (group II). The age of children ranged from 10 to 17 years. The children were hospitalized to the childrens' clinics of the NRCRM because of functional dis- orders and chronic somatic pathology. The psycho-emotional state of children was evaluated using the «non-exis- tent animal¼ test. It was analyzed for three symptoms - anxiety, aggressiveness and neuropsychiatric exhaustion and was evaluated by scoring points. Correction of the psychoemotional condition was carried out by the method of art therapy in the form of a serial drawing. Psychological testing was performed twice: at admission to the hospital and after the end of the art therapy. RESULTS: The results of the primary examination of the psycho-emotional state of children by the «non-existent ani- mal¼ test showed that in children - residents of radioactively contaminated territories the state of anxiety was reg- istered in all 57 children (100 %), the state of aggression - in 38 children (66.7%); exhaustion - in 37 children (64.9 %). In children who have been displaced from the zone of armed conflict in the south-east of Ukraine, the state of anxiety was also registered in all 56 children (100 %), the status of aggression was determined in 53 chil- dren (94.6 %), and the state of exhaustion - in 44 children (78.6 %). It was established that in children displaced from the combat zone in the Southeast of Ukraine, the quantitative indices of anxiety and aggression states were sig- nificantly higher than in children living in radioactively contaminated territories (p < 0.001), whereas nor by frequen- cy, nor by the degree of severity of exhaustion state they did not clearly differ (p > 0.05). Correlation analysis with the definition of Spearman's criterion did not reveal likely association between the content of 137Cs in the body of children - residents of radioactively contaminated territories and the peculiarities of their psycho-emotional state. CONCLUSIONS: The use of the art therapy method in the form of a serial drawing for children - residents of radioac- tively contaminated territories and children moved from the combat zone in the south-east of Ukraine, led to a sig- nificant positive effect, which was characterized by a decrease in the manifestations of symptoms of anxiety and aggressiveness. The state of exhaustion was less well corrected and its indices only had a tendency to improve. Thus, the method of art therapy in the form of a serial drawing is characterized by efficiency, simplicity of execution, low cost, it can be widely used in children's teams to correct disorders of the psycho-emotional state.