Clinical Characteristics of Acute Hematogenous Osteomyelitis With and Without Subperiosteal Abscesses in the Acute Care Setting.

BACKGROUND: Acute hematogenous osteomyelitis (AHO) is a common pediatric disease that can progress to involve nearby structures leading to complications including subperiosteal abscesses (SPAs). Those with SPAs, in particular, often require surgical intervention for complete treatment. Staphylococcus aureus remains one of the most common causes of AHO. With the emergence of community-associated methicillin-resistant Ataphylococcus aureus and its propensity to form abscesses, there has been an observed increased frequency of AHO with SPAs in children. Although magnetic resonance imaging (MRI) remains the gold standard of imaging for AHO, it is not readily available on a 24/7 basis and often necessitates procedural sedation in children. Delay in MRI and surgical intervention in patients with SPAs may lead to increased complications. The goal of this study is to identify, using clinical features easily obtained in the acute care setting, patients at high risk for AHO with SPAs who may benefit from emergent MRI and/or surgical intervention. DESIGN/METHODS: A retrospective chart review of patients aged birth to younger than 18 years diagnosed with AHO, who presented to a tertiary pediatric hospital from June 10, 2012, to November 1, 2017, were evaluated. Demographic, clinical, laboratory, and imaging data were collected. Patients were divided into 2 groups: AHO alone and AHO with SPAs. RESULTS: A final cohort of 110 subjects were included and analyzed. Of these, 73 (66%) were identified as having AHO alone and 37 (33.6%) as having AHO with SPAs. Patients had a higher risk of AHO with SPAs if they had a history of fever, decreased range of motion, edema, or elevated laboratory studies including white blood cell, absolute neutrophil count, erythrocyte sedimentation rate, and C-reactive protein. C-reactive protein was shown to have the highest correlation of AHO with SPAs, with an optimal cut point of 10.3 mg/dL, yielding a sensitivity of 67.7% and specificity of 77.6%. Patients with AHO with SPAs were at higher risk of having a positive blood culture for methicillin-resistant Staphylococcus aureus. CONCLUSIONS: Clinicians in acute care settings should have a high index of suspicion of AHO with SPAs in children with history of fever, decreased range of motion, or elevated laboratory values (white blood cell, absolute neutrophil count, erythrocyte sedimentation rate, and C-reactive protein). In particular, those with a significantly elevated CRP are at a higher risk for having AHO with SPAs in comparison with an uncomplicated AHO. However, with the significant overlap in historical and clinical variables in the initial presentations of children with AHO with and without SPAs, the clinical urgency in obtaining a magnetic resonance imaging must continue to be individualized based on overall clinical suspicion and availability of resources.

A Retrospective Look at a Cervical Spine Clearance Protocol in Pediatric Trauma Patients at a Level-1 Trauma Center.

BACKGROUND: Adult studies have demonstrated the efficacy of written protocols for clearance of the cervical spine. However, less than half of recently surveyed pediatric trauma centers report using a documented protocol. Little data exists on such protocols in pediatric populations, but interest remains because of potential reductions in radiation exposure, time to clearance, hospital stay, and specialist referral. However, missed injury can have devastating consequences. The purpose of this study is to examine the efficacy in detecting injury of an implemented cervical spine clearance protocol at a level-1 pediatric trauma hospital. METHODS: A retrospective review was performed on pediatric patients presenting as activated traumas to the emergency department of a single level-1 pediatric trauma hospital between May 2010 and October 2018. This institution has utilized a written cervical spine clearance protocol throughout this time. Presence of cervical spine injury, documented clearance, cervical spine imaging, and follow-up documentation were reviewed for any missed injuries. RESULTS: There were no missed cervical spine injuries. Five-hundred sixty-three clinically significant cervical spine injuries were identified, representing 16.5% of patients. Of these, 96 were fractures, dislocations, or ligamentous injuries, representing 2.8% of all patients. Most cervical spine clearances were performed by trauma surgery. Advanced imaging of the cervical spine was ordered for 43.2% of patients overall and trended down over time. CONCLUSION: Documented cervical spine clearance protocols are effective for detection of significant injury in pediatric trauma patients. This study suggests these protocols minimize risk of missed injury and may prevent unnecessary radiation exposure, delayed clearance, prolonged hospitalization, or unnecessary specialist referral. CLINICAL RELEVANCE: Utilization of a standard written protocol for cervical spine clearance likely prevents missed injury and helps to minimize radiation exposure in pediatric populations. Further research is needed on evaluation and management of pediatric cervical spine trauma.

Advances in Minimally Invasive Techniques in Pediatric Orthopedics: Percutaneous Spine Fracture Fixation.

Pediatric spine trauma presents unique management challenges. These injuries are often the result of high-energy mechanisms and are associated with other serious injuries that can complicate surgical and nonsurgical approaches. The pediatric population presents a host of challenges related to patient compliance, healing challenges, and patient tolerance of therapy. Percutaneous pedicle screw instrumentation, temporary fixation without fusion, continues to expand in its role of pediatric spine fracture treatment. Compared with open instrumentation and fusion, this technique addresses many of the previously mentioned challenges. Additional study is needed to evaluate the clinical utility of this approach in pediatric spinal fractures.

Management of concomitant scoliosis and tethered cord syndrome in non-spina bifida pediatric population.

BACKGROUND: The management of concomitant scoliosis and tethered cord syndrome in the non-spina bifida pediatric population is challenging. In the present study, we evaluate the efficacy of different treatment modalities and propose a treatment plan for the management of affected patients. METHODS: A systematic literature review was conducted by querying the MEDLINE, PubMed, Cochrane, EMBASE, Scopus, and Web of Science databases for papers published between January 1996 and June 2016 and reporting on concomitant scoliosis and tethered cord. We excluded animal studies, non-English papers as well as papers reporting on patients with multiple concomitant intraspinal anomalies such as spina bifida. RESULTS: Out of 1993 articles, only 13 met our inclusion criteria. These 13 articles described six main management approaches: Observation, cord untethering only, cord untethering followed by deformity correction, simultaneous cord untethering and deformity correction, and deformity correction without untethering. Selection of the best approach is a function of the patient's symptomatology and Cobb angle. CONCLUSION: We propose treatment plan for the management of patients with concomitant tethered cord syndrome and spinal deformity. Asymptomatic patients can be followed conservatively and managed as scoliosis patients with no need for untethering. Surgical management in a staged fashion seems appropriate in symptomatic patients with a Cobb angle less than 35°. In these patients, deformity can improve following untethering, thus sparing the patient the risks of surgical correction of scoliosis. Staged or non-staged cord untethering and curve correction seem to be adequate in symptomatic patients with Cobb angle >35° as these patients are likely to require both untethering and deformity correction.

Temporary Percutaneous Pedicle Screw Stabilization Without Fusion of Adolescent Thoracolumbar Spine Fractures.

BACKGROUND: Pediatric spine trauma often results from high-energy mechanisms. Despite differences in healing potential, comorbidities, and length of remaining life, treatment is frequently based on adult criteria; ligamentous injuries are fused and bony injuries are treated accordingly. In this study, we present short-term results of a select group of adolescent patients treated using percutaneous pedicle screw instrumentation without fusion. METHODS: An IRB-approved retrospective review was performed at a level 1 pediatric trauma center for thoracolumbar spine fractures treated by percutaneous pedicle screw instrumentation. Patients were excluded if arthrodesis was performed or if instrumentation was not removed. Demographics, injury mechanism, associated injuries, fracture classification, surgical data, radiographic measures, and complications were collected. Radiographs were analyzed for sagittal and coronal wedge angles and vertebral body height ratio and statistical comparisons performed on preoperative and postoperative values. RESULTS: Between 2005 and 2013, 46 patients were treated surgically. Fourteen patients (5 male, 9 female) met inclusion criteria. Injury mechanisms included 8 motor vehicle collisions, 4 falls, and 2 all-terrain vehicle/motorcycle collisions. There were 8 Magerl type A injuries, 4 type B injuries, and 2 type C injuries. There was 1 incomplete spinal cord injury. Implants were removed between 5 and 12 months in 12 patients and after 12 months in 2 patients. Statistical analysis revealed significant postoperative improvement in all radiographic measures (P<0.05). There were no neurological complications, 1 superficial wound dehiscence, and 2 instrumentation failures (treated with standard removal). At last follow-up, 11 patients returned to unrestricted activities including sports. Average follow-up was 9 months after implant removal and 19.3 months after index procedure. CONCLUSIONS: Adolescent thoracolumbar fractures present unique challenges and treatment opportunities different from the adult patient. We present a nonconsecutive series of 14 patients temporarily stabilized with percutaneous pedicle screw fixation for injuries including 3-column fracture dislocations and purely ligamentous injuries. Temporary fusionless instrumentation can provide successful management of select thoracolumbar spine injuries in pediatric trauma patients. LEVEL OF EVIDENCE: Level IV-Retrospective case series.

A Comparison of Early Clinical and Radiographic Complications of Iliac Screw Fixation Versus S2 Alar Iliac (S2AI) Fixation in the Adult and Pediatric Populations.

STUDY DESIGN: Retrospective chart review. OBJECTIVE: To compare short-term clinical and radiographic complications between iliac screw (IS) and S2 alar-iliac (S2AI) screw fixation techniques in the adult and pediatric populations. SUMMARY OF BACKGROUND DATA: Pelvic fixation with lumbosacral implants is in widespread practice with numerous indications. Several techniques for spinopelvic fixation have been described in the literature. Although the iliac screw technique is widely practiced, it presents several challenges, including the use of connectors, more lateral surgical dissection, and some complaints of pain over the posterior pelvis. The S2AI method has recently been proposed as an alternative technique that minimizes these complications. METHODS: We retrospectively reviewed the charts of 65 adult patients (43 IS, 22 S2AI) and 55 pediatric patients (40 IS/unit rod, 15 S2AI) in a consecutive series who underwent spinopelvic fixation. Acute, spinopelvic implant-related, and delayed complications, including persistent pain over the gluteal region occurring longer than 3 months postoperatively, were recorded from both clinical and radiographic encounters. Statistical analyses were performed among the adult and pediatric group, respectively, as well as a pooled cohort. RESULTS: The adult cohort found an 18.6% absolute risk reduction (ARR) in implant loosening (P=0.029) and a 21.1% ARR (P=0.05) in late pain with the S2AI method. In the pediatric population, the S2AI method demonstrated a 22.2% ARR (P=0.049) in both occurrence of revision surgery secondary to spinopelvic implant failure and late pain. In the pooled cohort, the S2AI method had a 13% ARR (P=0.033) in acute infections, 18.1% ARR (P=0.003) in implant loosening, 14.5% ARR (P=0.009) in revision surgery, 18.7% ARR (P=0.015) in late pain, and a 10.8% ARR (P=0.031) in delayed wound issues. CONCLUSIONS: The S2AI technique is associated with significantly less clinical and radiographic complications in both the pediatric and adult populations when compared with the iliac screws technique. LEVEL OF EVIDENCE: Level III.

An evaluation of posttraumatic stress disorder and parent stress in children with orthopaedic injuries.

OBJECTIVES: Trauma has more than physical effects on pediatric patients and their families. The purpose of this study was to evaluate pediatric orthopaedic trauma patients and patients with isolated nonoperative upper extremity (UE) fractures for emotional/psychologic symptoms associated with posttraumatic stress disorder (PTSD) and parent stress. METHODS: An institutional review board-approved prospective study of patients aged 8-18 years who sustained a traumatic injury or isolated UE fracture from October 2009 to May 2010 was performed. Demographic data were obtained and the Child PTSD Symptom Scale was used. The Parent Stress Index was used to evaluate the stress of the parents/guardian. For 80% power, we needed 32 per group. P value was set at <0.05. RESULTS: A total of 76 children and their parents/guardians participated in the study. The mean age was 12.6 years (8-17 years). There were 56 males (74%) and 20 females (26%). The average time since injury was 12 months (3-89 months). The prevalence of PTSD between the high-energy trauma patients and the low-energy nonoperative UE patients was not significant. Overall, 33% of the children had PTSD. Involvement in music was significant between patients with and without PTSD (P = 0.037) and may be protective against PTSD. CONCLUSIONS: PTSD commonly affects pediatric patients who sustain injuries as a result of a traumatic event, whether low- or high-energy mechanisms. We found no factors significantly associated with or predictive of PTSD and did not find an association of PTSD with parent stress. We need to maintain a high index of suspicion in pediatric trauma patients regardless of the energy associated with the traumatic event. LEVEL OF EVIDENCE: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.

The effects of screw orientation in severely osteoporotic bone: a comparison with locked plating.

BACKGROUND: Techniques such as varying screw insertion angles and the use of locked plating have been shown to improve the strength of fixation in bone. The effects of these methods is less clearly understood in bone of exceedingly poor quality. METHODS: Forty plate-bone constructs were assembled and divided into four groups of ten. Perpendicularly placed screws were placed in one group, convergently placed crossing screws were placed in a second group, an oblique end screw was placed in a third group, and a fourth group utilized perpendicularly placed locking screws in a locking plate. All test subjects were mounted and loaded in cantilever bending to the point of failure. Stiffness, initial load to failure, and maximal load tolerated were all analyzed. FINDINGS: All four groups demonstrated evidence of failure at similar loads (21.8-26.1N). The locked group was able to tolerate significantly higher loads overall (37.3N, P=.044). All three non-locked groups demonstrated similar failure patterns and load to failure. Locking constructs demonstrated a distinctly different failure pattern. No significant differences were detected with regard to screw orientation and load to failure. The group with an oblique end screw was significantly less stiff than the other three constructs (P=.017). INTERPRETATION: In a severely osteoporotic model, failure in cantilever bending at low forces will take place regardless of fixation methods used. The mechanism of failure is different in locked constructs compared to traditional constructs. The added benefit of oblique screw placement observed in healthy bone is not observed in osteoporotic bone.

Compression plating of pediatric femoral shaft fractures.

The authors conducted a retrospective review of 60 children under the age of 16 years with femoral shaft fractures treated with compression plate fixation. All patients were followed to hardware removal. The 100% union rate and low complication rate after compression plate fixation of pediatric femur fractures compared favorably to the literature of other treatment options. Compression plate fixation is a safe and effective treatment in children with both isolated femoral shaft fractures and those associated with multiple injuries.

Curve progression in scoliosis associated with Chiari I malformation following suboccipital decompression.

Nine children with scoliosis and Chiari I malformations were followed 1-11 years after suboccipital decompression. Eight also had syringomyelia. Despite initial curve stabilization, at final follow-up eight curves were of the magnitude to require spinal fusion. Neither bracing nor secondary neurosurgical procedures arrested progressive curves.