RESUMEN
Diet has been increasingly shown to be of therapeutic benefit for patients with inflammatory bowel diseases (IBD), especially Crohn's disease (CD). Yet dietary guidelines are nonexistent. Moreover, diets tailored to Puerto Ricans with IBD living on the island, have not been developed and tested. The rising prevalence of IBD in Puerto Rico warrants exploring the use of diet as part of the treatment strategies for these patients [1]. Here, we describe the study design of "Dieta Anti-Inflamatoria" or DAIN, a parallel two-arm randomized pilot trial aiming at testing the efficacy of IBD-Anti-inflammatory diet (IBD-AID) adapted for adults with CD living in Puerto Rico (clinical trial registration number: NCT05627128). We tailored the IBD-AID to the local cuisine preferences and food availability by creating and adapting recipes consistent with the IBD-AID principles [2,3]. In focus groups with a Community Research Advisory Panel and one-on-one consultations with implementation experts, we identified several aspects of the intervention to adapt before the implementation. The objectives of the stakeholder/expert-informed adaptation were to improve feasibility and compliance while developing the culturally tailored dietary intervention. DAIN was designed for adults living in Puerto Rico with CD and geared to be affordable, appropriate, and acceptable for patients with mild-to-moderate CD. The significance of this work is the validation of culturally appropriate nutritional guidelines to help manage CD symptoms. DAIN provides a blueprint for a comprehensive nutritional program that can be adapted to regional preferences and local food availability allowing wider implementation of diet as an adjunct treatment in diverse clinical settings.
RESUMEN
Se exponen cronológicamente los hechos importantes,así como sus protagonistas desde los orígenes de la oftalmología en Cuba, hasta su pleno desarrollo. Desde inicios del Siglo XIX la Historia Médica Cubana recoge la experiencia del Dr Fernández Cruzado en una amaurosis del ojo izquierdo, además de la creación de la primera sala hospitalaria dedicada a enfermedades de los ojos, obra debida a la iniciativa del Conde de Villanueva y dirigida por González Morillas. De forma sintética se describen los aspectos y mayores logros de la obra oftalmología de Carrón Du Villard, Enrique López,Luis de la Calle, Horacio Ferrer y en especial la del Dr Juan Santos Fernández, matancera y figura cimera de la oftalomología en nuestro continente, así como la de su sobrino también notable oftalmólogo Francisco Ma Fernández.
We expose, in chronological order, the main historical facts and also their protagonists, from the beginning of ophthalmology in Cuba until its full development. Since the beginnings of the XIX century, Cuban medical history gathers the experience of Dr Fernandez Cruzado in an amaurosis of the left eye, and besides that the creation of the first hospital room dedicated to eye diseases, due to the Count of Villanueva's initiative and directed by Gonzalez Morillas. In a synthetic way, we expose the main aspects and bigger attainments of Carron Du Villard's, Enrique Lopez's, Luis de la Calle's, Horacio Ferrer's work, and especially the work of Dr Juan Santos Fernández, from Matanzas, and an outstanding figure of Ophthalmology in our continent, and also the work of his nephew, the prominent ophthalmologist Francisco María Fernández.
