RESUMEN
The synthesis of a Schiff base-based chemosensor, denoted as H6L, was accomplished through the condensation reaction of Isophthalohydrazide and 2,6-dihydroxybenzaldehyde in an ethanol solvent. The resulting compound was further characterized using 1H and 13C nuclear magnetic resonance (NMR) spectroscopy, as well as high-resolution mass spectrometry (HRMS). Extensive research has been conducted on several facets of metal sensing phenomena, revealing that the Schiff base H6L demonstrates discerning and expeditious fluorescence sensing characteristics specifically towards Al (III) in acetonitrile. The purported method detects Al (III) can be ascribed to the suppression of photo-induced electron transfer (PET) and the enhanced chelation-induced fluorescence (CHEF). The stoichiometry of metal-ligand complexes (2:1) was determined using Job's plots titrations, HRMS and subsequently confirmed using NMR titration studies. The H6L sensors demonstrated remarkable fluorescence sensing capabilities in acetonitrile, with a low detection limit (LOD) of 0.44 µM. This LOD is suitably low for the detection of Al3+, which is commonly found in many environmental and biological systems. Fluorescence lifetime measurement provides additional evidence of complexation of H6L with Al (III). The reversibility of the sensor was demonstrated through the introduction of pyrophosphate (PPi), which forms a complex with aluminium ions, thereby releasing the chemo sensor for subsequent utilization. The findings suggest that H6L has the potential to serve as a viable probe for the detection and identification of Al3+ ions.
RESUMEN
Experiences of adversity can generate positive psychological effects alongside negative impacts. Little research to date has evaluated predictors of post-traumatic growth in mental or community healthcare workers during the COVID-19 pandemic. Following a survey of 854 community and mental healthcare staff in the United Kingdom in July to September 2020, multiple linear regression was used to determine the association between hypothesised risk and protective factors (personal, organisational and environmental variables) and total scores on the Post-traumatic Growth Inventory-Short Version. Positive self-reflection activities, black and minority ethnic status, developing new healthcare knowledge and skills, connecting with friends and family, feeling supported by senior management, feeling supported by the UK people, and anxiety about the personal and work-related consequences of COVID-19 each significantly independently predicted greater post-traumatic growth. Working in a clinical role and in mental healthcare or community physical healthcare predicted lower post-traumatic growth. Our research supports the value of taking an organisational growth-focused approach to occupational health during times of adversity, by supporting staff to embrace opportunities for personal growth. Valuing staff's cultural and religious identity and encouraging self-reflective activities, such as mindfulness and meditation, may help to promote post-traumatic growth.
