Comparison between sex and polymorphisms on FKBP5: perception of quality of life in non-syndromic patients. A cross-sectional study.

This study aimed to compare factors that influence perception of quality of life (QoL) in patients scheduled for orthognathic surgery. This was a cross-sectional study with 91 participants from two universities in Curitiba. The orthognathic quality of life questionnaire (OQLQ) was used to assess patients' perceptions of their QoL. Sociodemographic data were collected and facial profiles classified into classes I, II, and III. DNA was extracted from oral mucosal cells and markers rs3800373 and rs1360780 for FKBP prolyl isomerase 5 were genotyped. Statistical analysis was performed using Kruskal-Wallis, Mann-Whitney, and chi-squared tests, with a significance level of 5%. There was a negative impact on general perception of QoL in females (p = 0.019) and in the domains of "oral function" (p=0.032) and "awareness of the deformity" (p=0.009). In the dominant model (CC/CT), the presence of at least one C allele for the rs1360780 marker had a negative impact on QoL in the "facial aesthetics" domain (p = 0.037). The negative impact on QoL was greater in females than in males. The perception of QoL was more negative in individuals with rs1360780 polymorphism on the FKBP5 gene and a CC/CT genotype than it was in those with a TT genotype.

Delayed removal of maxillary third molar displaced into the maxillary sinus.

INTRODUCTION: The present article reports the late removal of a wisdom tooth displaced into the maxillary sinus associated with the curettage of the adjacent infection tissue, under general anesthesia. CASE DESCRIPTION: A male patient, 42 years-old, was forwarded to remove a right wisdom tooth which was displaced into the right maxillary sinus for 10 months. The patient reported that the tooth was tried to be removed using odontosection in two moments without any success. Since then, the patient has been having (applicants) episodes of sinusitis. It had been planned to remove the tooth and the cleaning of the right maxillary sinus. The surgical procedure was done through the Caldwell-Luc access, followed by the removal of the dental fragments which were into the maxillary sinus and curettage of the cavity in order to remove the granulation tissue, associated to copious irrigation. CONCLUSION: The surgical removal of the tooth displaced into the maxillary sinus associated with the sinus curettage was successfully achieved, solving the patient complaints.