Actinomyces-induced Osteomyelitis of the Mandible - A Rare Disease.

BACKGROUND: Actinomyces species are commensal oral cavity flora that can cause jaw osteomyelitis. Osteomyelitis of the jaw by Actinomyces is rare, and its presentation can be confused with many different pathologies. CASE PRESENTATION: This is the case of a 61-year-old female with breast cancer and on chemotherapy as well as non-invasive carcinoma of the tongue who initially presented to the dentist with white spots in the right mandible near the incisors associated with right mandible pain and swelling. Actinomyces-induced osteomyelitis of the mandible was diagnosed. The patient was treated with penicillin V for 6 weeks along with a course of hyperbaric oxygen therapy, which resulted in the complete resolution of the infection. CONCLUSION: In summary, jaw osteomyelitis caused by Actinomyces should always be part of the differential diagnosis; as these organisms are commensal flora, the symptoms manifested are nonspecific, and such a diagnosis could be easily missed, resulting in delay of care and disease progression.

Pre-Workout-Induced Pancreatitis.

The use of dietary supplements, including pre-workout formulations, has gained widespread popularity among individuals engaged in sports and fitness. This case report presents a unique instance of pre-workout-induced pancreatitis in a previously healthy young adult. The patient, a 35-year-old male, presented to the emergency department with abdominal pain, elevated pancreatic enzymes, and characteristic radiological findings indicative of acute pancreatitis. The patient's history revealed no prior predisposing factors for pancreatitis such as alcohol consumption or gallstone disease. Extensive diagnostic evaluation excluded other potential causes leading to the suspicion of his pre-workout supplement as the source. Pre-workout supplements contain a blend of stimulants, amino acids, and other metabolic ingredients designed to enhance exercise and muscle performance. Research shows that some of these ingredients, such as amino acids, induce metabolic chain reactions which may damage pancreatic cells. However, there is extremely limited literature regarding these amino acids in combination such as in workout supplements. This case prompts an examination of the potential adverse effects of pre-workout supplements, highlighting the need for increased vigilance among healthcare providers and consumers alike. As the use of these products grows, further research is warranted to allow for safe commercial distribution and to protect consumers from serious harm.