Antimicrobial Activity of Milk Whey in Different Mammals.

Antimicrobial activity of milk whey in different mammals against Candida albicans yeast cells was studied by a spectrophotometric method. The activity increased in the order goat→horse→camel→cow→human→mouse. The level of whey activity in mice was higher by 3 and 10 times than in humans and goats, respectively. Similar changes were noted for activity of the whey fraction <100 kDa containing a complex of antimicrobial polypeptides, and there was a direct correlation between these two parameters (r=0.881; p<0.05). The total activity of whey had a high degree of correlation with the content of serum albumin (r=0.992); in mice, the level of serum albumin in the milk whey was close to that in blood serum. Interspecific differences between the activity of whey in mammals may be associated with qualitative and quantitative variability of the antimicrobial polypeptide composition, as well as their synergistic or antagonistic interaction with each other.

[Radiological analysis of size of bone elements of the temporomandibular joint in children and adolescents with class II malocclusion]. / Analiz razmerov kostnykh elementov visochno-nizhnechelyustnogo sustava u detei i podrostkov s distal'noi okklyuziei.

BACKGROUND: The aim of the study was to assess the ratio of bone elements of the temporomandibular joint (TMJ) in children and adolescents with distal occlusion according to cone-beam computed tomography (CBCT). MATERIAL AND METHODS: CBCT of the TMJ was analyzed in 121 patients aged 12-18 years, which were divided into two age groups: group I - children aged 12-15 years (62 cases in total, of which 47 patients with distal occlusion and 15 patients with physiological occlusion) and II group - adolescents aged 15-18 years (59 cases, of which 48 patients with distal occlusion and 11 patients with physiological occlusion). CBCT of the temporomandibular joint was performed by the standard method in the position of habitual occlusion and maximally open mouth. The size of the TMJ joint space in the anterior, upper and posterior sections was determined by the method of Rabukhina N.A., the analysis of the ratio of the bone elements of the TMJ was carried out using the Craniometry program. RESULTS: The size of the joint space and the angle ß of the temporomandibular joint in the anterior section on the right and left in children aged 12-15 with distal occlusion is increased compared to children with physiological occlusion in the position of habitual occlusion. In adolescents 15-18 years old with distal occlusion, the size of the TMJ joint space is increased in the anterior section on the right and left and reduced in the posterior section on the right, angle α is reduced on the right and left, angle ß is reduced on the right, angle γ is increased on the right compared to adolescents with physiological occlusion. The revealed deviations indicate the presence of violations in the ratio of the bone elements of the TMJ, which are aggravated with age. CONCLUSION: Analysis of the results obtained during CBCT in children and adolescents allows us to correct the plan of orthodontic treatment and predict its results.

[Cephalometric study of 9-15 years old patients with maxillofacial anomalies and cerebral palsy]. / Tsefalometricheskie parametry u patsientov v vozraste 9-15 let s zubocheliustnymi anomaliiami i detskim tserebral'nym paralichom.

AIM: To study the morphological state of the maxillofacial system in children with cerebral palsy. MATERIAL AND METHODS: The frequency and prevalence of dental anomalies was studied in 30 9-15 years old children with cerebral palsy. For the registration of maxillofacial anomalies, the Bjork assessment method was used. The severity of sagittal incisive disocclusion and the reverse sagittal incisal disocclusion was measured by the magnitude of the sagittal slit. RESULTS: The study revealed no age-dependent correlation of lower canines and second premolars roots growth. The parameters of the cerebral part of the skull measured on the CT-bases lateral cephalograms were significantly less than normal rates except for the length of the posterior part of the skull. CONCLUSION: The morphological changes that determined the formation of sagittal and vertical incisive disocclusions were defined: the reduction of total anterior morphological face height (N-Me) and anterior upper morphological face height (N-SpP) and the increase in the anterior lower morphological face height (SpP-Me) which are characteristic features for patients with incisive sagittal and vertical diocclusion.