Cardiac effects of deferasirox in transfusion-dependent patients with myelodysplastic syndromes: TELESTO study.

Iron overload from repeated transfusions has a negative impact on cardiac function, and iron chelation therapy may help prevent cardiac dysfunction in transfusion-dependent patients with myelodysplastic syndromes (MDS). TELESTO (NCT00940602) was a prospective, placebo-controlled, randomised study to evaluate the iron chelator deferasirox in patients with low- or intermediate-1-risk MDS and iron overload. Echocardiographic parameters were collected at screening and during treatment. Patients receiving deferasirox experienced a significant decrease in the composite risk of hospitalisation for congestive heart failure (CHF) or worsening of cardiac function (HR = 0.23; 95% CI: 0.05, 0.99; nominal p = 0.0322) versus placebo. No significant differences between the arms were found in left ventricular ejection fraction, ventricular diameter and mass or pulmonary artery pressure. The absolute number of events was low, but the enrolled patients were younger than average for patients with MDS, with no serious cardiac comorbidities and a modest cardiovascular risk profile. These results support the effectiveness of deferasirox in preventing cardiac damage caused by iron overload in this patient population. Identification of patients developing CHF is challenging due to the lack of distinctive echocardiographic features. The treatment of iron overload may be important to prevent cardiac dysfunction in these patients, even those with moderate CHF risk.

Significado del cuidado espiritual de enfermería en pacientes en cuidados paliativos

Objetivo: describir el significado de cuidado espiritual que brinda el personal de enfermería a los pacientes en cuidados paliativos Métodos: se trata de un estudio cualitativo, descriptivo; con enfermeras de instituciones de salud de segundo nivel de atención en el estado de Guanajuato. Selección de participantes por muestreo por conveniencia con 9 participantes. Colecta de datos a través de entrevista semiestructurada audiograbada, análisis de datos temático; se respetaron los criterios éticos, los participantes firmaron un consentimiento informado. Resultados: emergieron seis temas: Cuidar las necesidades de los pacientes, Significado de espiritualidad, Acompañamiento, alivio y apoyo, Cuidando el respeto de las creencias, Dificultades vividas en el cuidado espiritual y Necesidad de cambios en el cuidado espiritual. Conclusiones: el significado del cuidado espiritual de enfermería considera la conexión con la naturaleza y el universo y las creencias y prácticas; esta conexión nace en el cuidado de las necesidades propias que fomentan confort, la espiritualidad da sentido al cuidado espiritual como el acompañar, aliviar y apoyar teniendo en cuenta el respeto de las creencias. Se encuentran dificultades en el cuidado espiritual y una necesidad de cambios en el mismo para poder incorporarlo en el cuidado cotidiano.

Objective: to describe the meaning of spiritual care provided by nurses to palliative care patients. Methods: this is a qualitative, descriptive study; with nurses from second level health care institutions in the state of Guanajuato. Selection of participants by convenience sampling with 9 participants. Data collection through semi-structured audio-recorded interview, thematic data analysis; ethical criteria were respected, participants signed an informed consent. Results: six themes emerged: caring for patients' needs, Meaning of spirituality, Accompaniment, relief and support, Caring for respect of beliefs, Difficulties experienced in spiritual care and Need for changes in spiritual care. Conclusions: the meaning of nursing spiritual care considers the connection with nature and the universe and beliefs and practices; this connection is born in caring for one's needs that foster comfort, spirituality gives meaning to spiritual care as accompanying, relieving and supporting taking into account respect for beliefs. Difficulties are found in spiritual care and a need for changes in it in order to incorporate it into daily care.

Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1-Risk Myelodysplastic Syndromes: A Randomized Trial.

Background: Iron chelation therapy (ICT) in patients with lower-risk myelodysplastic syndromes (MDS) has not been evaluated in randomized studies. Objective: To evaluate event-free survival (EFS) and safety of ICT in iron-overloaded patients with low- or intermediate-1-risk MDS. Design: Multicenter, randomized, double-blind, placebo-controlled trial (TELESTO). (ClinicalTrials.gov: NCT00940602). Setting: 60 centers in 16 countries. Participants: 225 patients with serum ferritin levels greater than 2247 pmol/L; prior receipt of 15 to 75 packed red blood cell units; and no severe cardiac, liver, or renal abnormalities. Intervention: Deferasirox dispersible tablets (10 to 40 mg/kg per day) (n = 149) or matching placebo (n = 76). Measurements: The primary end point was EFS, defined as time from date of randomization to first documented nonfatal event (related to cardiac or liver dysfunction and transformation to acute myeloid leukemia) or death, whichever occurred first. Results: Median time on treatment was 1.6 years (interquartile range [IQR], 0.5 to 3.1 years) in the deferasirox group and 1.0 year (IQR, 0.6 to 2.0 years) in the placebo group. Median EFS was prolonged by approximately 1 year with deferasirox versus placebo (3.9 years [95% CI, 3.2 to 4.3 years] vs. 3.0 years [CI, 2.2 to 3.7 years], respectively; hazard ratio, 0.64 [CI, 0.42 to 0.96]). Adverse events occurred in 97.3% of deferasirox recipients and 90.8% of placebo recipients. Exposure-adjusted incidence rates of adverse events (≥15 events per 100 patient treatment-years) in deferasirox versus placebo recipients, respectively, were 24.7 versus 23.9 for diarrhea, 21.8 versus 18.7 for pyrexia, 16.7 versus 22.7 for upper respiratory tract infection, and 15.9 versus 0.9 for increased serum creatinine concentration. Limitations: The protocol was amended from a phase 3 to a phase 2 study, with a reduced target sample size from 630 to 210 participants. There was differential follow-up between treatment groups. Conclusion: The findings support ICT in iron-overloaded patients with low- to intermediate-1-risk MDS, with longer EFS compared with placebo and a clinically manageable safety profile. Therefore, ICT may be considered in these patients. Primary Funding Source: Novartis Pharma AG.

Adolescent With Spontaneous Splenic Rupture as a Cause of Hemoperitoneum in the Emergency Department: Case Report and Literature Review.

Spontaneous rupture of the spleen is a rare clinical condition that usually presents as a complication of a background pathology and can become a life-threatening condition if it is not diagnosed in time. We present the case of a 15-year-old girl with abdominal pain and clinical data of hypovolemic shock. The simple tomographic study revealed deformation of the splenic architecture and hemoperitoneum. Surgery demonstrated splenic rupture with ptosis spleen and intraperitoneal free blood. The anatomopathological examination showed the presence of splenomegaly and findings suggestive of peliosis. It also highlights the known causes related to spontaneous splenic rupture.

Relación entre género y calidad de vida laboral en profesionales de salud / Relationship between gender and quality of working life related to health professionals

En este estudio, se buscó establecer la relación entre el género y la evaluación de la Calidad de Vida Laboral (CVL) en profesionales de salud. Para llevarlo a cabo, se seleccionaron aleatoriamente 322 personas en una institución de salud en Guadalajara, México. La satisfacción con su CVL se evaluó mediante el instrumento validado CVT-GOHISALO. Se evidenció la insatisfacción de las mujeres ante la desigualdad de oportunidades. Además, las mujeres del estudio demostraron con significancia estadística que se encuentran más satisfechas que los varones en el desarrollo personal que han logrado a través de su trabajo y en la administración de su tiempo libre.

This paper aims to establish the relationship between gender and quality of working life assesment in health professionals in Guadalajara, Mexico. 322 people were sampled in a health institution. The satisfaction related to their quality of working life, was assessed through CVT-GOHISALO instrument. As a result, women dissatisfaction was revealed with opportunities inequality. In addition, sampled women showed through statiscal significance to be more satisfied than men, talking about personal development achieved through work and free time management.

Validez y confiabilidad de la escala de salud mental positiva / Validity and reliability based on the scale of possitive mental health

El objetivo del presente estudio consistió en demostrar la validez y confiabilidad de la Escala de Salud Mental Positiva en 400 trabajadores del Sector Salud de Michoacán, México. Para este propósito se realizaron los siguientes procesos: 1) De acuerdo a la teoría y a los indicadores, se definió lo que se requería medir; 2) Se revisaron los instrumentos existentes; 3) Se generó, revisó y decantó una serie de Ítems; 4) Se aplicó la Escala de Salud Mental a la muestra; 5) Se evaluaron los Ítems para obtener su validación y confiabilidad. La estructura factorial de la escala se evaluó mediante un análisis con el método de componentes principales y rotación Varimax. Los resultados muestran una confiabilidad de 0,862, considerándose adecuado para su aplicación en la población mexicana.

This paper focus on showing the validity and reliability based on the Scale of Positive Mental Health in 400 Health dpt workers from Michoacan, Mexico. For this purpose some procedures were performed as follow: 1. According to the indicators, it was defined what it was required measure; 2. Current instruments were reviewed; 3. Number of items were generated, decided and reviewed; 4. Mental health scale was applied for population sampled; 5. Items were assessed for its validation and reliability. Scale factorial structure was assessed using factor analysis and taking into account main components method and rotation. The results show 0.862 high reliability considered appropriate to be used for Mexican population.

Factores psicosociales y síndrome de burnout en personal de enfermería de una unidad de tercer nivel de atención a la salud / Psychosocial factors and burnout syndrome in nurses of a unit of tertiary health care

El OBJETIVO fue determinar la relación entre los factores psicosociales laborables y el síndrome de Burnout en personal de enfermería de una unidad de tercer nivel de atención a la salud. MATERIAL Y MÉTODOS: Se trata de un estudio observacional, transversal y analítico en personal de enfermería de una unidad de tercer nivel de atención a la salud. Los datos se captaron con el instrumento de factores psicosociales de Silva y el MBI. Se analizaron con el apoyo del SPSS. RESULTADOS: Participaron 163 personas de 21 servicios de la unidad de atención; 88% eran mujeres, 41,4% laboraba en el turno matutino y 47,5% perciben la presencia de factores psicosociales negativos en su área de trabajo, siendo lo más frecuente las exigencias laborales, remuneración del rendimiento y condiciones inadecuadas en su lugar de trabajo. En cuanto al Burnout, 33,3% presentaba agotamiento emocional, 50,8% baja realización personal y 17,9% despersonalización. El agotamiento emocional se relacionó (p < a 0,05) con seis de las ocho áreas de los factores psicosociales evaluados CONCLUSIÓN: Se confirmó la relación entre los factores psicosociales laborales y el síndrome de Burnout.

The OBJECTIVE was to determine the relationship between psychosocial factors and working burnout syndrome in nursing staff of a unit of tertiary health care. MATERIAL Y METHODS: It is an observational, cross-sectional analytical study in nursing staff of a unit of tertiary health care. The data were collected with the instrument of psychosocial factors Silva and MBI. It was analyzed with the support of SPSS. RESULTS: A total of 163 people from 21 services care unit; 88% were women, 41,4% worked in the morning shift and 47,5% perceive the presence of negative psychosocial factors in their work area, where work demands are the most frequent, performance reward and inadequate conditions in work place. Regarding the Burnout, 33,3% had emotional exhaustion, 50,8% reduced personal accomplishment and depersonalization 17,9%. Emotional exhaustion was associated (p <0,05) with six of the eight areas of psychosocial factors evaluated CONCLUSION: the relationship between psychosocial factors and confirmed Burnout syndrome.

Relación entre calidad de vida en el trabajo y síntomas de estrés en el personal administrativo universitario / Relationship between quality of life at work and stress symptoms in university administrative staff

OBJETIVO: Analizar la relación de la Calidad de Vida en el Trabajo (CVT), con los síntomas del estrés en el personal administrativo de una universidad pública del Ecuador. MATERIAL Y MÉTODOS: Diseño correspondiente con el paradigma cuantitativo, transversal, analítico y relacional. RESULTADOS: Del análisis descriptivo de la muestra de 447 trabajadores, 59.3% mujeres y 40.7% hombres; promedio de edad es 46 años. Tiempo promedio en el cargo es 18 años. Se aplicó cuestionarios: "CVT-GOHISALO" y "Evaluación de Síntomas de Estrés". El 76% de los trabajadores administrativos advierte la presencia de los síntomas fisiológicos de estrés en niveles medio, alto y muy alto. A su vez los síntomas de comportamiento social, intelectuales, laborales y psicoemocionales presentaron niveles bajos de estrés. No hay presencia de trastornos mentales o psicoemocionales. Más de la mitad de la población estudiada estaría en vulnerabilidad al riesgo del desequilibrio en la CVT; la tercera parte de la población estudiada obtuvo una alta satisfacción en el trabajo. CONCLUSIÓN: Este estudio fue inédito, demostró la asociación significativa entre la CVT y los síntomas de estrés. Los resultados permitieron plantear estrategias predictivas para mejorar la CVT en el contexto universitario; alineándose a las políticas de Estado, promover el "buen vivir".

OBJECTIVE: To analyze the relationship of the Quality of Life at Work (CVT) with symptoms of stress on the administrative staff of a public university in Ecuador. MATERIALS AND METHODS: Design corresponding to the quantitative, crosssectional, analytical and relational paradigm. RESULTS: Descriptive analysis of the sample of 447 workers in total, 59.3 % female and 40.7 % male; average age is 46 years old. The average time in office is 18 years. Questionnaires were applied: "CVT-GOHISALO" and "Assessment of Stress Symptoms" 76% of administrative workers, admit to the presence of the physiological symptoms of stress in the medium, high and very high levels. In turn the symptoms of social, intellectual, occupational and psycho-emotional behavior, had low levels of stress. No presence of mental or psycho-emotional disorders. More than half of the studied population would be vulnerable to the risk of imbalance in the quality of life at work. third of the study population, had a high job satisfaction. CONCLUSION: This study was unpublished and showed a significant association between CVT and symptoms of stress. The results allowed to propose strategies to improve predictive quality of life at work in the university context; aligning state policies to promote the "good life".

[Respiratory symptoms caused by the use of electrocautery in physicians being trained in surgery in a Mexican hospital]. / Síntomas respiratorios causados por el uso del electrocauterio en médicos en formación quirúrgica de un hospital de México.

In order to determine the frequency of respiratory symptoms among residents from surgical specialties dures exposed to the electrocautery smoke, a cross-sectional study was conducted in February 2012. 50 third-year residents from different surgical specialties coming from a third-level hospital belonging to the Institute of Security and Social Services of the State Workers in Jalisco, Mexico, were included. The subject selection was non-probabilistic. A questionnaire on respiratory symptoms developed in Cuba was used for data collection. The most common symptoms were sensation of a lump in the throat (58%), and a sore throat (22%). The specialty with the highest rate of exposure was neurosurgery (24.1 min/surgical procedure). All, the physicians from this specialty had respiratory symptoms. We conclude that the cauterization smoke may be considered a risk for developing respiratory symptoms among physicians with surgical specialties.

Síntomas respiratorios causados por el uso del electrocauterio en médicos en formación quirúrgica de un hospital de México / Respiratory symptoms caused by the use of electrocautery in physicans being trained in surgery in a Mexican hospital

Con el objetivo de determinar la frecuencia de síntomas respiratorios entre los residentes de especialidades quirúrgicas expuestos al humo del electrocauterio, se realizó un estudio transversal durante el mes de febrero de 2012. Se incluyeron 50 médicos residentes del tercer año, de diferentes especialidades quirúrgicas, de un hospital de tercer nivel perteneciente al Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado ubicado en Jalisco, México. La selección de sujetos fue no probabilística. Para la recolección de datos, se empleó el cuestionario de síntomas respiratorios desarrollado en Cuba. Los síntomas más comunes fueron sensación de cuerpo extraño (58%) y ardor faríngeo (22%). La especialidad con mayor índice de exposición fue la de neurocirugía (24,1 min/acto quirúrgico). La totalidad de los médicos de esta especialidad tuvieron algún síntoma respiratorio. Se concluye que la inhalación del humo del cauterio puede constituir un riesgo para desarrollar síntomas respiratorios entre los médicos de especialidades quirúrgicas.

In order to determine the frequency of respiratory symptoms among residents from surgical specialties dures exposed to the electrocautery smoke, a cross-sectional study was conducted in February 2012. 50 third-year residents from different surgical specialties coming from a third-level hospital belonging to the Institute of Security and Social Services of the State Workers in Jalisco, Mexico, were included. The subject selection was non-probabilistic. A questionnaire on respiratory symptoms developed in Cuba was used for data collection. The most common symptoms were sensation of a lump in the throat (58%), and a sore throat (22%). The specialty with the highest rate of exposure was neurosurgery (24.1 min/surgical procedure). All, the physicians from this specialty had respiratory symptoms. We conclude that the cauterization smoke may be considered a risk for developing respiratory symptoms among physicians with surgical specialties.

Síndrome serotoninérgico / Serotonin syndrome

El síndrome serotoninérgico (SS) se caracteriza por la presencia de disfunción autonómica, deterioro neuromuscular y alteraciones en el estado mental. El diagnóstico es clínico y por laboratorio. El tratamiento es mediante medidas de apoyo a base de líquidos, hipotermia, benzodiacepinas y, cuando lo amerite, intubación y ventilación mecánica. El pilar de la intervención farmacológica es ciproheptadina, un antagonista central H1, con un antagonismo periférico 5-HT2A. El medicamento disponible sólo se puede administrar por vía oral, por lo que en enfermos críticos debe administrarse a través de sonda nasoyeyunal. El objetivo de este trabajo es presentar un caso de SS y revisar la literatura al respecto.

The serotonin syndrome (SS) is characterized by a spectrum of signs characterized by autonomic dysfunction, neuromuscular impairment, and alterations in mental status. The diagnosis of the serotonin syndrome is clinical and by laboratory evaluation. Treatment is with active cooling and benzodiazepines to control agitation, and intubation, especially in patients with severe hyperthermia and delirium. The mainstay of pharmacologic intervention is cyproheptadine, a centrally acting H1-antagonist, with a prominent peripheral 5-HT2A antagonism. The drug is only available orally, and if the patient is unable to swallow, the drug should be administered nasogastrically. The objective of this paper is report a case of Serotonin Syndrome and review the literature related to this disease.

Alteraciones electrocardiográficas en hemorragia subaracnoidea / Electrocardiographic alterations in subarachnoid hemorrhage

Los enfermos con hemorragia subaracnoidea (HSA) presentan con frecuencia alteraciones electrocardiográficas (ECG), las más frecuentes son alargamiento del segmento QT, ondas T negativas, elevación o inversión del segmento ST y ondas U. La inversión de las ondas T asociada a la prolongación del QT se correlaciona con alteraciones de la contractilidad ventricular y es una indicación para practicar ecocardiograma. Se reporta el caso de un paciente con HSA secundaria a ruptura de aneurisma intracraneal que presentó cambios electrocardiográficos, enfatizando en la patogénesis de éstos y el impacto que tienen en el comportamiento clínico y la evolución.

Electrocardiographic (EGC) changes have been frequently observed in patients with subarachnoid hemorrhage (SAH). The most frequent anomalies reported are prolonged of the QT interval, negative T waves, elevation or inversion of the ST segment and U wave. T wave inversion associated to QT interval prolongation is related to alterations in ventricular contraction indicating that echocardiographic screening is required. We report the case of a patient with SAH secondary to intracranial aneurism rupture who showed electrocardiographic changes, emphasizing the pathogenesis of the latter and the impact they have in both clinical manifestations and evolution.

Social support, burnout syndrome and occupational exhaustion among Mexican traffic police agents.

The consequences of work-related stress on health are worrisome, and by the same token, so is Burnout Syndrome. However, it has been shown that social support can prevent, reduce or even combat individuals' responses to stress. A descriptive, transverse study was carried out with the objective of determining the prevalence of both Burnout Syndrome and receiving social support for traffic police in Mexico. 875 traffic police participated in the study, men and women alike, from all work shifts, day and night. Three questionnaires were administered: one to record sociodemographic and professional data, as well as the Maslach Burnout Inventory and the modified Diaz Veiga Social Resources Inventory. Our data analysis obtained frequencies and percentages and also identified associations between the study's variables. The prevalence of Burnout Syndrome was found to be 54.9% among the study's participants. The social support networks designated as "low or poor" were shown to be associated with Burnout Syndrome, with p values less than .05, an odds ratio (OR) greater than 1 and a confidence interval that did not include the number one. In spite of the strong network of social support reported by participants, it seems that those social effects were not strong enough to combat Burnout Syndrome, and some resolution strategy ought to be implemented at the individual, group and organizational levels.

Factores psicosociales laborales y Síndrome de Burnout, diferencias entre hombres y mujeres docentes de secundaria, Zona Metropolitana de Guadalajara, México / Occupational psychosocial and burnout syndrome: differences among male and female high school teachers, metropolitan area of Guadalajara, México

Objetivo: identificar las diferencias de los factores psicosociales laborales y el Síndrome de Burnout en hombres y mujeres docentes de secundaria de la Zona Metropolitana de Guadalajara, Jalisco, México. Material y métodos: el estudio es observacional transversal yanalítico en una muestra de probabilística de 186 mujeres y 171hombres. Se utilizó la escala de Maslach Burnout Inventory y la Batería de Factores Psicosociales en el Trabajo Académico. Resultados: 84,1% de mujeres y 77,2% de hombres presentaron alguna dimensión de la escala de Maslasch “quemada”. Ambosidentificaron la presencia de factores psicosociales laborales, encontrando relación (p < 0,05) con el Síndrome de Burnout en los hombres con las condiciones de trabajo, el contenido y características de la tarea y la interacción social y en las mujeres con exigencias laborales. Conclusión: hombres y mujeres perciben por igual la presencia de factores psicosociales laborales, existiendo diferencias por género entre estos y el Síndrome de Burnout.

Objective: To identify the sex differences in labor psycho-social factorsand the Burnout Syndrome prevalence in middle school teachers, from Guadalajara Metropolitan Zone. Material and methods: This is an cross-sectional and analytical study with a probabilistic sample of 186 women 171 men. The scale of Maslach Burnout Inventory (MBI) and the Psycho-social Factors for Academic Work Inventory were used.Results: 84.1% of women and 77.2% of men presented some altered dimension on the MBI scale. Both groups identified the presence of negative labor psycho-social factors. In men was found a relationship (p <.05) among the burnout syndrome and the work conditions, workcontent, task characteristics and social interaction and in the women withlabor exigencies. Conclusion: Men and women perceive presence of negative labor psycho-social factors, but there are differences between them and theBurnout syndrome occurrence.

Evaluación de dos estrategias de educación nutricional vía radio en Guadalajara, México / Evaluation of two strategies for nutritional education using radio programs in Guadalajara, Mexico

La modificación de los conocimientos y de las actitudes desde la óptica de la comunicación persuasiva en salud vía radio ha reportado resultados alentadores para los planificadores sanitarios. El objetivo fue medir el efecto de una estrategia educativa en los conocimientos y en las actitudes, utilizando el radio, en dos comunidades marginadas. Es una intervención educativa vía radio en dos comunidades marginadas y socioeconómicamente homogéneas en Guadalajara, Jalisco, México. Se seleccionaron al azar dos comunidades marginadas y se formaron dos grupos de radioescuchas, se midieron los conocimientos y las actitudes sobre contenidos de educación nutricional para la salud mediante un instrumento codificado y estructurado. El primer grupo "A", de 37 sujetos, fue organizado y expuesto a la dinámica del radio foro durante los 4 meses que dura el proyecto. El grupo "B" (n = 33), no organizado, se expuso al proyecto radiofónico según su propia dinámica cultural. La mediana del grupo A para Conocimientos y Actitudes (CA), en la pre medición, fue de 56,8 y, para la pos medición, fue de 74,1 (W: p = -0,05). Para el grupo B, los CA fueron de 53 y 59,2, respectivamente (W: p = -0,05). Así se refuerzan las ventajas del radio foro como estrategia comunicativa en salud en el área de la nutrición humana

[Evaluation of two strategies for nutritional education using radio programs in Guadalajara, Mexico]. / Evaluación de dos estrategias de educación nutricional vía radio en Guadalajara, México.

Modifying knowledge and attitudes through persuasive communication in health via radio has produced encouraging results for public health planners. This study's objective was to measure the effect of an educational strategy on knowledge and attitudes towards nutrition in two marginalized communities in Guadalajara, Mexico. Two communities were randomly selected. In each community a group of individuals was invited to be exposed to radio broadcasts. Using a coded and structured instrument, knowledge and attitudes towards the contents of nutritional education for health were measured before and after the intervention in both groups. Group A (n = 37) was organized and exposed to the dynamics of the radio forum throughout the 4 months during which the project lasted. Group B (n = 33) was not organized, and listened to the radio program according to its own cultural dynamics. Median knowledge and attitudes (KA) for group A was 56.8 in the pre-test and 74.1 in the post-test (W: p = -0.05). In group B the KA results were 53.0 and 59.2, respectively (W: p = -0.05). The results emphasize the advantages of the radio forum as a health communications strategy for human nutrition.

¿Cual es la relación del Pityrosporum ovale con la papilomatosis reticulada y confluente de Gougerot y Carteaud?: comentarios a propósito de cuatro estudios histológicos y micológicos / Which is the relationship of Pityrosporum ovale and reticulated and confluent papilomatosis of Gougerot and Carteaud?

Se discute si hay relación etiológica del Pityrosporum ovale en la génesis de la papilomatosis reticulada y confluente de Gougerot y Carteaud. Se trata de puntualizar las diferencias clínicas y micológicas con otras patologías relacionadas con la levadura. Se concluye que es un cuadro bien individualizado, debido a trastornos de la queratinización, y que no hay participación de Pityrosporum ovale

Vasculitis leucocitoclástica cutánea como marcador de enfermedades sistémicas / Dermic leucocytoclastic vasculitis as a marker of systemic diseases

Se estudiaron 58 pacientes con vasculitis leucocitoclástica cutánea. La lesión dermatológica más frecuente fue púrpura, seguida de púrpura palpable. El estudio histopatológico de piel confirmó la lesión vascular inflamatoria: se encontraron dos patrones diferentes del infiltrado celular: 1) con predominio de neutrófilos y 2) con predominio de linfocitos como manifestación de la evolución dinámica del proceso inflamatorio. De acuerdo a las enfermedades generalmente asociadas se agruparon los pacientes en los siguientes grupos: enfermedades autoinmunes, reacción por medicamentos, neoplasias, infecciones e idiopáticas