In vivo evaluation of rotator cuff internal impingement during scapular plane abduction in asymptomatic individuals.

Internal impingement-or entrapment of the undersurface of the rotator cuff tendon against the glenoid during overhead activities-is believed to contribute to articular-sided tears. However, little is known about internal impingement outside athletic populations. Therefore, the objectives of this study were to (1) describe glenoid-to-footprint distances and proximity centers during dynamic, in vivo motion in asymptomatic individuals, and (2) determine the extent to which these measures differed between individuals with and without a rotator cuff tear. Shoulder kinematics were assessed in 37 asymptomatic individuals during scapular plane abduction using a high-speed biplane radiographic system. Glenoid-to-footprint distances and proximity center locations were calculated by combining the kinematics with computerized tomography-derived bone models. Glenoid-to-footprint contact was presumed to occur when the minimum distance was less than the estimated labral thickness. The condition of the supraspinatus tendon (intact, torn) was assessed using ultrasound. Minimum distances and proximity centers were compared over humerothoracic elevation angles (90°, 110°, 130°, 150°) and between supraspinatus pathology groups using two-factor mixed model analysis of variances. Glenoid-to-footprint minimum distances decreased consistently across elevation angles (p < 0.01) without a significant difference between groups. Contact was estimated to occur in all participants. Proximity centers were generally located on the anterior half of the rotator cuff footprint and on the posterosuperior glenoid. Statement of Clinical Significance: Internal impingement during overhead motions may be a prevalent mechanism of rotator cuff pathology as contact appears to be common and involves the region of the rotator cuff footprint where degenerative rotator cuff tears are thought to originate.

Correspondence between scapular anatomical coordinate systems and the 3D axis of motion: A new perspective on an old challenge.

Several scapular anatomical coordinate systems have been reported in the literature to describe shoulder kinematics. Unfortunately, the use of different conventions hinders comparison across studies. Further, inconsistencies between a coordinate system and the scapula's 3D axis of motion means that scapular motion will be incorrectly attributed to axes about which it did not rotate. The objectives of this study were to: 1) determine the extent to which the axes of four common scapular coordinate system conventions correspond to the 3D axis of scapular motion (i.e., instantaneous helical axis, IHA), and 2) report the prevalence of scapulothoracic gimbal lock for each convention. Shoulder kinematics were tracked during scapular plane abduction in 45 participants using biplane videoradiography. Scapulothoracic kinematics were described using the original convention proposed by van der Helm, the convention recommended by the International Society of Biomechanics (ISB), a glenoid-based coordinate system, and a glenoid-oriented coordinate system. The 3D angle was calculated between the IHA and each axis of the four conventions (IHA-axis angular deviations). A repeated measures ANOVA was used to compare IHA-axis angular deviations between conventions. The glenoid-oriented and ISB conventions resulted in the smallest and largest IHA-axis angular deviations, respectively (21.7°±3.6° vs. 30.5°±5.2°, p < 0.01). Gimbal lock was approached in 17.8% of participants when using the original convention, 2.2% when using the ISB convention, and 0% when using the glenoid-based or -oriented conventions. These findings suggest the glenoid-oriented coordinate system may be worthy of further consideration when investigating shoulder kinematics during scapular plane abduction.

Dosage-Adjusted Resistance Training in Mice with a Reduced Risk of Muscle Damage.

Progressive resistance training (PRT), which involves performing muscle contractions against progressively greater external loads, can increase muscle mass and strength in healthy individuals and in patient populations. There is a need for precision rehabilitation tools to test the safety and effectiveness of PRT to maintain and/or restore muscle mass and strength in preclinical studies on small and large animal models. The PRT methodology and device described in this article can be used to perform dosage-adjusted resistance training (DART). The DART device can be used as a standalone dynamometer to objectively assess the concentric contractile torque generated by the ankle dorsiflexors in mice or can be added to a pre-existing isokinetic dynamometry system. The DART device can be fabricated with a standard 3D printer based on the instructions and open-source 3D print files provided in this work. The article also describes the workflow for a study to compare contraction-induced muscle damage caused by a single bout of DART to muscle damage caused by a comparable bout of isometric contractions (ISOM) in a mouse model of limb-girdle muscular dystrophy type 2B/R2 (BLAJ mice). The data from eight BLAJ mice (four animals for each condition) suggest that less than 10% of the tibialis anterior (TA) muscle was damaged from a single bout of DART or ISOM, with DART being less damaging than ISOM.