[Serum creatine phosphokinase as a predictor of upper limb amputation in electrical trauma]. / Soderzhanie kreatinfosfokinazy v plazme krovi kak prediktor amputatsii verkhnei konechnosti pri elektrotravme.

OBJECTIVE: To study the relationship between serum creatine phosphokinase and outcomes of injury in victims with electrical burns. MATERIAL AND METHODS: Among 40 patients with electrical injury, 7 (18%) ones underwent upper limb amputation. There were 37 (92.5%) men and 3 (7.5%) women aged 37 (28; 47) years. We analyzed total serum creatine phosphokinase and MB fraction on the first day in patients with and without amputations. RESULTS: Total serum creatine phosphokinase exceeded the upper reference value in 11 out of 33 patients without amputation and in all 7 patients with limb amputation (p=0.001). Patients with limb amputation had significantly higher total serum creatine phosphokinase and MB fraction (p<0.001 and p=0.030, respectively). Logistic regression equation showed that high total serum creatine phosphokinase significantly influenced amputation rate (p<0.001), as evidenced by odds ratio (42.7, 95% CI 3.5-514.8). ROC analysis revealed the cut-off value of total serum creatine phosphokinase (950 IU/L). Sensitivity was 100% (63; 100), specificity - 94% (86; 94), positive predictive value - 78% (49; 78), negative predictive value - 100% (92; 100). CONCLUSION: Total serum creatine phosphokinase depends only on severity of electrical and flame burns. Serum creatine phosphokinase is a predictor of upper limb amputation in patients with electrical injury. Total serum creatine phosphokinase ≥ 950 IU/L is significant for upper limb amputation (in CK-MB fraction within the reference values).

[Acute local radiation lesions and their consequences (contingency in flaw inspection)]. / Ostrye mestnye luchevye porazheniia i ikh posledstviia (neshtatnaia situatsiia pri defektoskopicheskikh rabotakh).

Illustrated with case history (patient F), the authors represented diagnosis, prognosis, treatment, long-term consequences of local radiation lesions.

[Microsurgical autotransplantation of tissues in emergency surgery]. / Mikrokhirurgicheskaia autotransplantatsiia tkanei v neotlozhnoi khirurgii.

Results of microsurgical transplantation of 177 autotransplants in 167 patients with tissues defects of different origin and location are presented. Surgeries were urgent and elective with 96.6% survival of autotransplants. Short- and long-term results of surgery were assessed. It is concluded that microsurgical techniques of treatment are more reliable and cost-effective than traditional ones. Expediency of microsurgical autotransplantation in urgent surgery is demonstrated.

[The action of karbogal on the complement system under model conditions and in an animal experiment]. / Vozdeistvie karbogala na sistemu komplementa v model'nykh usloviiakh i v éksperimente na zhivotnykh.

The influence of dimethylperfluorocyclohexane (carbogal) on the hemolytic activity of human blood serum complement was studied in vitro. It has been show that different effects of carbogol on the complement depend on the serum lipid composition. Endotracheal administration of carbogal to rats results in a significant reduction of complement activity in the animal's blood. Significant changes in the hemolytic activity of the complement recorded 21 days after the endotracheal administration of the compound are, probably, associated with the complement depletion after its activation by carbogal particles or with disorders in the complement component synthesis by macrophages.