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1.
Pak J Biol Sci ; 22(11): 554-563, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31930834

RESUMEN

BACKGROUND AND OBJECTIVE: Terbutaline is a ß-agonist that used as growth promoters to improved carcass chemical composition of chicks without residues. The purpose of the present investigation is exploring the effect of different dietary levels and duration of terbutaline on the productive performance, biochemical and carcass quality traits including residue of acres broiler. MATERIALS AND METHODS: A total of 150 one-day-old arbor acres broiler chicks were allotted into 5 groups (3 replicates per each). Group 1 was fed on the basal diet without supplement, while groups 2-5 fed on the basal diet supplemented by 5 or 10 mg terbutaline kg-1 diet during 1-42 or 21-42 days, respectively. RESULTS: When handling the dietary levels and duration of terbutaline, results of the present study showed that10 mg terbutaline kg-1 diet during the whole experimental period is a more effective dose for improvement of growth performance with significant (p<0.05) increased serum protein and breast muscles relative weight compared with control. Also, 10 mg terbutaline kg-1 diet during the whole experimental period significantly (p<0.05) increase d CP% (crude protein%) and CHO% (carbohydrate%) of breast muscle and significantly (p<0.05) decreased fat% (ether extract%) of breast muscle and abdominal fat relative weight compared with control. Meanwhile, 5 mg terbutaline kg-1 diet during 1-42 or 21-42 days has no significant effect on the above-mentioned parameters. Regarding residue, the terbutaline residue wasn't detected in broiler meat. CONCLUSION: It can conclude that 10 mg terbutaline kg-1 diet during the whole experimental period is a better dose and duration for improving growth performance, the chemical composition of breast muscle and carcass traits of broiler chickens with no terbutaline residue in breast muscle.


Asunto(s)
Pollos/crecimiento & desarrollo , Pollos/metabolismo , Terbutalina/administración & dosificación , Agonistas de Receptores Adrenérgicos beta 2/administración & dosificación , Alimentación Animal/análisis , Crianza de Animales Domésticos , Fenómenos Fisiológicos Nutricionales de los Animales , Animales , Animales Recién Nacidos , Dieta/veterinaria , Suplementos Dietéticos , Residuos de Medicamentos/análisis , Lípidos/sangre , Carne/análisis , Terbutalina/análisis
3.
Environ Toxicol Pharmacol ; 60: 118-127, 2018 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29705371

RESUMEN

The present study aimed to investigate the toxic effect of aflatoxin B1 (AFB1) and the effectiveness of a biological mycotoxin binder (Nutritox®) in detoxifying aflatoxicosis. Ninety one-day-old chicks were chosen and divided into 3 groups. The first group received standard basal diet only, the second group received a basal diet with AFB1 (0.25 mg/kg diet), and the third group received a basal diet with AFB1 (0.25 mg/kg diet) and Nutritox® (1 kg/ton diet). AFB1 feed contamination significantly reduced growth performance and deteriorated FCR. Moreover, it significantly increased serum AST, ALT, and malondialdehyde and significantly decreased serum total protein, albumin, globulin, SOD, CAT activities and glutathione peroxidase gene expression as well. Aflatoxin residues were detected in the liver tissues. Furthermore, the liver and kidney of AFB1 treated group showed pathological changes. The supplementation of Nutritox® significantly reduced aflatoxin levels in the liver and counteracted the negative effects of AFB1.


Asunto(s)
Aflatoxinas/toxicidad , Pollos/genética , Perfilación de la Expresión Génica/métodos , Enfermedades de las Aves de Corral/inducido químicamente , Probióticos/administración & dosificación , Animales , Enfermedad Hepática Inducida por Sustancias y Drogas/genética , Enfermedad Hepática Inducida por Sustancias y Drogas/prevención & control , Pollos/crecimiento & desarrollo , Contaminación de Alimentos , Regulación de la Expresión Génica/efectos de los fármacos , Riñón/química , Riñón/efectos de los fármacos , Hígado/química , Hígado/efectos de los fármacos , Enfermedades de las Aves de Corral/genética , Probióticos/farmacología
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