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J Antimicrob Chemother ; 68(9): 1941-50, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-23612569

RESUMEN

OBJECTIVES: To perform a multifactorial exploration of the aetiology of peritonsillar abscess (PTA) in adults, in order to develop greater clinical understanding of the condition and improve management. DESIGN: A literature review exploring key pathogens, predisposing host factors and current pathogenic hypotheses. METHODS: A PubMed search for articles published between January 1980 and January 2012 using the terms 'peritonsillar abscess AND microbiology', 'peritonsillar abscess AND pathophysiology' and 'peritonsillar abscess AND etiology'. RESULTS: Major pathogens in PTA are opportunistic microflora. Group A streptococcal PTA infections present differently from polymicrobial PTA. A number of host factors influence the conditions required for the pathogenesis of PTA. CONCLUSIONS: PTA is clinically distinct from acute tonsillitis and occurs in people with a chronic underlying susceptibility. Targeting host factors, including oral hygiene, antibiotic use and smoking, may prevent PTA. Re-education of clinicians concerning the aetiology of PTA is necessary for appropriate disease management.


Asunto(s)
Infecciones Oportunistas/etiología , Infecciones Oportunistas/fisiopatología , Absceso Peritonsilar/etiología , Absceso Peritonsilar/fisiopatología , Susceptibilidad a Enfermedades , Humanos , Absceso Peritonsilar/terapia
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