Identifying extended psychosis phenotypes at school: Associations with socio-emotional adjustment, academic, and neurocognitive outcomes.

The main goal of the present study was to explore the latent structure of extended psychosis phenotypes in a representative sample of adolescents. Moreover, associations with socio-emotional adjustment, academic achievement, and neurocognition performance across the latent profiles were compared. Participants were 1506 students, 667 males (44.3%), derived from random cluster sampling. Various tools were used to measure psychosis risk, subjective well-being, academic performance, and neurocognition. Based on three psychometric indicators of psychosis risk (schizotypal traits, psychotic-like experiences, and bipolar-like experiences), four latent classes were found: non-risk, low-risk, high reality distortion experiences, and high psychosis liability. The high-risk latent groups scored significantly higher on mental health difficulties, and negative affect, and lower on positive affect and well-being, compared to the two non-risk groups. Moreover, these high-risk groups had a significantly higher number of failed academic subjects compared to the non-risk groups. In addition, no statistically significant differences in efficiency performance were found in the neurocognitive domains across the four latent profiles. This study allows us to improve the early identification of adolescents at risk of serious mental disorder in school settings in order to prevent the incidence and burden associated with these kinds of mental health problems.

The role of self-referencing in true and false recognition in young people and healthy older people.

BACKGROUND: Given the uneven results about the role self-referencing plays in false recognition, we planned an experiment that would allow us to analyze whether self-referencing affects false recognition, and its relationship with healthy aging. METHOD: A sample of healthy older people (n = 30) and another sample of young people (n = 38) rated whether 40 personality-trait adjectives (20 with a positive valence and 20 with a negative valence) described them or not (self-referencing condition). They then took a recognition test of these adjectives along with 40 other new adjectives. Next, they rated whether 40 other different adjectives described a third person or not (other-referencing condition), and then performed another similar recognition test. These two conditions were counter-balanced across participants. RESULTS: The results clearly showed that self-referencing produces both an increase in true recognition and a decrease in false recognition in both samples. CONCLUSIONS: Our results support the idea that self-referencing reduces false recognition by using conscious monitoring strategies, and that self-referencing is a suitable cognitive method for enhancing older individuals’ impaired memory.

The Role of Recollection and Familiarity in Nondemented Parkinson's Patients.

The aim of the current study was to examine if recollection and familiarity decline in nondemented Parkinson's patients. To do so we compared a sample of older people with Parkinson's disease (n = 32) to a control sample of healthy older people (n = 32) on an associative recognition task in which we manipulated the repetition of the pairs during the study phase (half of the pairs were presented once and half twice) to obtain corrected estimates of recollection, familiarity, and false recognition based on the logic of the process-dissociation procedure. The results clearly show that recollection is impaired but familiarity is preserved in nondemented Parkinson's patients. The results show that memory for pairs in Parkinson's patients relies largely on the familiarity of each item and not on a precise recollection of associative information, supporting the idea that recollection-based monitoring processes are impaired in these patients.

The effects of healthy aging, amnestic mild cognitive impairment, and Alzheimer's disease on recollection, familiarity and false recognition, estimated by an associative process-dissociation recognition procedure.

Given the uneven experimental results in the literature regarding whether or not familiarity declines with healthy aging and cognitive impairment, we compare four samples (healthy young people, healthy older people, older people with amnestic mild cognitive impairment - aMCI -, and older people with Alzheimer's disease - AD -) on an associative recognition task, which, following the logic of the process-dissociation procedure, allowed us to obtain corrected estimates of recollection, familiarity and false recognition. The results show that familiarity does not decline with healthy aging, but it does with cognitive impairment, whereas false recognition increases with healthy aging, but declines significantly with cognitive impairment. These results support the idea that the deficits detected in recollection, familiarity, or false recognition in older people could be used as early prodromal markers of cognitive impairment.

An overall decline both in recollection and familiarity in healthy aging.

BACKGROUND: In the area of recognition memory, the experimental data have been inconsistent about whether or not familiarity declines in healthy aging. A recent meta-analysis concluded that familiarity is impaired when estimated with the remember-know procedure, but not with the process-dissociation procedure. METHOD: We present an associative recognition experiment with remember-know judgments that allow us to estimate both recollection and familiarity using both procedures in the same task and with the same participants (a sample of healthy older people and another sample of young people). Moreover, we performed a within-subjects manipulation of the type of materials (pairs of words or pairs of pictures), and the repetition or not of the pairs during the study phase. RESULTS: The results show that familiarity, estimated using both estimation procedures, declines significantly with age, although the effect size obtained with the process-dissociation procedure is significantly smaller than the one obtained with the remember-know procedure. CONCLUSIONS: Our results show that aging is associated with significant decreases both in recollection and, to a lesser extent, familiarity.