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J Fr Ophtalmol ; 42(7): 730-738, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-31103354

RESUMEN

PURPOSE: To examine levels of serum thyroid stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), vitamin D, vitamin B12 (B12), folic acid (FA), c-reactive protein (CRP), and hemoglobin in pseudoexfoliation glaucoma (XFG) and primary open angle glaucoma (POAG) patients. MATERIALS AND METHODS: A hospital-based, prospective, cross-sectional study was conducted from October 2016 through June 2017 and October 2017 through January 2018. The number of patients was 33 in the control group, 29 in the XFG group and 77 in the POAG group. RESULTS: The mean±SD levels of TSH, fT4, fT3, vitamin D, B12, FA, CRP, and hemoglobin were 2.52±2.07 mU/l, 1.15±0.24ng/dl, 3.16±3.37pg/ml, 20.83±14.06ng/ml, 318.29±115.48pg/ml, 7.7±4.01ng/ml, 3.78±3.83mg/l, 13.36±2.08g/dl in control group respectively. The levels for the XFG patients were as follows: TSH 2.02±1.16 mU/l, fT3 3.10±0.46pg/ml, fT4 1.18±0.19ng/dl, vitamin D 20.02±19.30ng/dl, B12 302.13±142.44pg/ml, FA 9.55±3.67ng/ml, CRP 3.69±3.22mg/l, and hemoglobin 13.58±1.38g/dl. In the POAG group, serum levels of TSH, fT4, fT3, vitamin D, B12, FA, CRP, and hemoglobin were 1.88±1.13 mU/l, 1.23±0.14ng/dl, 3.16±0.43pg/ml, 15.7±12.0ng/ml, 297.71±150.66pg/ml, 9.1±4.1ng/ml, 4.16±5.12mg/l, and 14.09±1.45 respectively. Only mean vitamin D levels show a significant difference between the control group and POAG (p=0.015). CONCLUSION: POAG patients show decreased Vitamin D levels. Our study shows no significant differences in other biochemical markers between XFG, POAG and control subjects.


Asunto(s)
Proteína C-Reactiva/metabolismo , Síndrome de Exfoliación/sangre , Glaucoma de Ángulo Abierto/sangre , Hemoglobinas/metabolismo , Hormonas Tiroideas/sangre , Vitaminas/sangre , Adulto , Anciano , Anciano de 80 o más Años , Proteína C-Reactiva/análisis , Estudios de Casos y Controles , Estudios Transversales , Síndrome de Exfoliación/complicaciones , Femenino , Ácido Fólico/sangre , Glaucoma de Ángulo Abierto/complicaciones , Hemoglobinas/análisis , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Pruebas de Función de la Tiroides , Vitamina B 12/sangre , Vitamina D/sangre , Adulto Joven
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