1.
Pneumologie
; 74(7): 436-442, 2020 07.
Artículo
en Alemán
| MEDLINE
| ID: mdl-32492720
2.
Pneumologie
; 68(7): 492-5, 2014 Jul.
Artículo
en Alemán
| MEDLINE
| ID: mdl-25006842
RESUMEN
Augmentation therapy in Alpha-1 Antitrypsin Deficiency aims to reduce the progression of lung emphysema, to reduce exacerbation frequency, and to improve quality of life. This expert statement briefly summarizes the most important treatment studies performed in patients with Alpha-1 Antitrypsin Deficiency and severe lung emphysema. Indications and contraindications for long-term intravenous augmentation therapy with human Alpha-1 Antitrypsin are derived from the available study results. Safety issues and the controversies of this topic are discussed in detail.