1.
Analyst
; 142(12): 2090-2093, 2017 Jun 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28425520
RESUMEN
An innovative chemical strategy integrated in a miniaturized electrochemical device was developed for sensitive detection of a pathogen genome (HBV virus) without any amplification step. The results show a limit of detection comparable to the standard qRT-PCR method (20 copies per reaction), paving the way to future development of genetic PoC devices addressing automatized and low-cost molecular diagnostics.