Event-related potentials of food-induced blindness in the rapid serial visual presentation paradigm.

Emotion-induced blindness is known as the impairment in the identification of targets that follow shortly after emotional distractors in the rapid serial visual presentation (RSVP) paradigm. Besides negative or erotic stimuli, food distractors have also been found to elicit a similar effect. This indicates an attentional bias for food stimuli in the temporal dimension of visual attention, which is highly relevant in the context of eating behaviour. So far, the neural mechanisms of this food-induced blindness are widely unknown. In the present study (N = 53), we investigated event-related potentials (ERPs) in response to food distractors and non-food targets in a single-target RSVP task. Automatic capture of visual attention by task-irrelevant food distractors was evident in enhanced Distractor Negativity (N2) and Early Food Positivity (P1). However, food distractors did not elicit a P3b. Thus, apparently, not the encoding of food distractors in working memory but alternative attentional processes are responsible for the food-induced blindness. Reduced target P3b reflected errors in target identification but was unaffected by the preceding distractor. In contrast, target N2 was specifically reduced for unidentified targets preceded by food distractors. Presumably, the attentional capture of food distractors may have caused a reduction of target N2, thereby contributing to the impairment in target identification. However, future research is needed to confirm this assumption and bridge the gap between the food-induced blindness on the behavioural level and the attentional capture of food stimuli reflected in the distractor ERPs.

Attentional tuning of valent word forms.

Using event-related brain potentials (ERPs), we tested the hypothesis of valent word forms (Kissler et al., 2006, Prog Brain Res) stating that the mere visual shapes of emotional words acquire valence through numerous co-occurrences with affective activation over an experienced reader's life. Thereby, associations between neuronal representations of visual word forms and affect are strengthened. If so, selective attention to a specific level of the valence of single visual words should not only pre-activate neuronal representations of that level of valence, but this activation should also spread to the associated word forms. This should improve their processing and/or affective discrimination. In a valence-detection task, N = 53 participants made speeded responses only to words of the current target level of valence (negative, neutral, or positive), which varied across separate blocks. We focused on posterior visual P1 and N170 components, two well-established ERP markers of low-level and structural word form processing, respectively. P1 increased from negative over neutral to positive words; this effect was stronger in target compared to nontarget words. N170 was larger for emotional compared to neutral target words, whereas nontarget words showed a strong reverse pattern. The P1 effect for target words and the N170 effect for nontarget words both were driven by good task performers in terms of fast hit responses. Results support the idea of valent word forms that can be tuned by selective attention to valence, which implies both, facilitated affective discrimination and processing of target words, and inhibition of the processing of nontarget words.

Personality subtypes in adults with social anxiety disorder - novelty seeking makes the difference.

BACKGROUND: Up to now several subtypes of social anxiety disorder (SAD) have been proposed. METHODS: In the present study, we used a cluster analytic approach to identify qualitatively different subgroups of SAD based on temperament characteristics, that is, harm avoidance (HA) and novelty seeking (NS) dimensions of Cloninger's Temperament and Character Inventory. RESULTS: Based on a large, diverse clinical sample (n = 575), we found evidence for two distinct subgroups of SAD: a larger (59%) prototypic, inhibited cluster characterized by high HA and low NS, and a smaller atypic, and comparatively more impulsive cluster characterized by medium to high HA and increased NS. The subgroups differed regarding a variety of sociodemographic and clinical variables. While the prototypic SAD subtype suffered from more severe SAD and depressive symptoms, suicidal ideation, and reduced social functioning, the atypic NS subtype showcased higher reproductive behaviour, self-directedness and -transcendence, comparatively. Additional hierarchical logistic regression highlights the contribution of age and education. CONCLUSIONS: Our results valuably extend previous evidence for the existence of at least two distinct subtypes of SAD. A better knowledge of the characteristic differences in prototypic behaviour, personality, coping strategies and comorbidities between the identified (and further) subtypes can contribute to the development of effective prevention interventions and promotes the conceptualization of tailored treatments.

Attention to affect 2.0: Multiple effects of emotion and attention on event-related potentials of visual word processing in a valence-detection task.

Here we continue recent work on the specific mental processes engaged in a valence-detection task. Fifty-seven participants responded to one predefined target level of valence (negative, neutral, or positive), and ignored the remaining two levels. This enables more precise fine-tuning of neuronal pathways, compared to valence categorization where attention is divided between different levels of valence. Our group recently used valence detection with emotional words. Posterior P1 and N170 effects in the event-related potential (ERP) supported the idea of valent word forms that can be tuned by selective attention to valence. Here we report findings on three distinct posterior N2 components, P300, N400, and the late positive potential (LPP). Target but not nontarget words showed an arousal effect (emotional > neutral) on left-side early posterior negativity (180-280 ms). In contrast, an arousal effect on a sharp N2 deflection in left-minus-right difference ERPs (230-270 ms), suggesting facilitation of lexical access for emotional words, was independent of target status. This also applied to increased medial parieto-occipital N2 (260-300 ms) specific to negative words, indicating attentional capture. Medial-central N400 was specifically enhanced for negative nontarget words, further supporting attentional capture. The typical LPP arousal effect was observed, being stronger and more left-lateralized in target words. An exploratory finding concerned a broad component-overarching ERP valence effect (250-650 ms). Independent of target status, ERPs were more positive for positive than negative words. Combined with our previous results, data suggest multiple loci of emotion-attention interactions in valence detection.

Social anxiety disorder with comorbid major depression - why fearful attachment style is relevant.

Individuals with social anxiety disorder (SAD) often suffer from comorbid major depressive disorder (MDD), which goes along with increased clinical and functional impairment. There has been little research on underlying differences regarding childhood adversities and attachment styles between individuals with SAD with and without comorbid MDD. In the present study, the consecutive sample comprised 612 SCID-diagnosed participants. Of these, n = 472 (62.3% women, 40.7 ± 13.8 years) showed SAD and comorbid MDD (SAD-MDD group) and n = 140 (47.9% women, 43.7 ± 14.7 years) showed just SAD (SAD group). The two groups were compared regarding SAD symptom severity (Social Phobia Inventory; SPIN), childhood adversities (Adverse Childhood Experience Questionnaire; ACE) and attachment styles (Attachment Style Questionnaire, ASQ). The SAD-MDD group reported significantly more severe SAD symptoms (p = .002, d = 0.30), more childhood adversities (p < .001, d = 0.35) and a higher level of fearful attachment style (p < .001, d = 0.30). Group significantly moderated the association between fearful attachment style and SAD symptom severity (ß = .292, p < .05) but not between preoccupied attachment style and SAD symptom severity (ß = -.184, p = .124; R2adj = .168, p < .05). Fearful attachment style mediated the association between childhood adversities and SAD symptom severity in the SAD-MDD group. Our study could identify a specific significance of fearful attachment style for the association between negative childhood experiences and social anxiety symptoms in SAD-MDD. Findings have specific implications for the therapeutic relationship.

Helpless against food cues: the influence of pro- and anti-sugar videos on instrumental food-seeking behaviour in a Pavlovian-to-instrumental transfer paradigm.

OBJECTIVE: External food cues can trigger food seeking by means of associative Stimulus-Outcome-Response learning mechanisms. These mechanisms can contribute to cued overeating. The present study aims at investigating if (cued) food-seeking behaviour can be influenced by pro- and anti-sugar videos. DESIGN: Participants (N = 81) completed a Pavlovian-to-instrumental transfer (PIT) task: in an instrumental training, they learned associations between button presses and resulting sugary or sugar-free snacks. In a subsequent Pavlovian training, the snacks were paired with different cues. During the following transfer test, participants performed free button presses to win snacks while the cues were present or not. MAIN OUTCOME MEASURES: The number of button presses for the different snacks in the transfer test was analysed. RESULTS: We observed an outcome specific PIT effect, i.e. higher response rates for cued snacks. The videos did not affect the PIT effect. However, exploratory analyses revealed that the anti-sugar video led to fewer button presses for sugary snacks (compared to the pro-sugar video). CONCLUSION: While snack-seeking behaviour was unaffected by the video's messages in the presence of food cues, in the absence of food cues there was evidence for a reduction of sugary snack choices by the anti-sugar video.

Effects of the calorie content of visual food stimuli and simulated situations on event-related frontal alpha asymmetry and event-related potentials in the context of food choices.

Approach and avoidance tendencies play an important role in everyday food choices when choosing between high-caloric, rather unhealthy, and low-caloric, rather healthy options. On a neuronal level, approach and avoidance motivation have been associated with asymmetrical activity of the frontal cortex, often quantified by alpha power averaged over several seconds of resting electroencephalogram (EEG). Going beyond the analysis of resting EEG, the present study aimed to investigate asymmetrical frontal activity in direct response to food stimuli in an event-related design and in combination with event-related potentials (ERPs). Therefore, a sample of 56 young and healthy participants completed a food choice task. They were asked to choose from a selection of high-caloric and low-caloric foods which they would want to eat on a normal day (baseline), when being on a diet, and in a reward situation. On the behavioural level, there was a clear preference for low-caloric foods. Well in line with that, time-frequency analyses of alpha asymmetry revealed relatively stronger temporary (950-1175 ms) left-hemispheric frontal activity, that is, a stronger approach tendency, in response to low-caloric as compared to high-caloric foods. Furthermore, larger P300 for low-caloric foods indicated an increased task relevance of low-caloric foods in the baseline and the reward situation. In contrast, the late positive potential (LPP), an index of subjective value, was larger for high-as compared to low-caloric foods, reflecting the intrinsic rewarding properties of high-caloric foods. ERPs, but not frontal alpha asymmetry, were influenced by the situational context.

Attention please: ERP evidence for prime-target resource competition in the neutral-target variant of affective priming.

Using event-related potentials we examined the mechanisms that underlie the influence of affective context information on evaluative judgments in affective priming (AP). Participants (N = 44) evaluated a priori neutral target ideographs that were preceded by 800-ms negative, neutral or positive prime pictures. We observed a significant AP effect (APE), with more positive target ratings for targets following positive versus negative primes, with neutral primes lying in between. A greater individual APE was associated with increased attention for the primes, indicated by larger amplitudes of parietal positive slow wave (PSW) and more pronounced prime affect discrimination mirrored in affect-specific variations of parieto-occipital prime P1 and parietal prime P2, P300, and PSW amplitudes. This confirms previous theoretical and empirical work suggesting that the size of the APE critically depends on the extent of prime-elicited affective activation. Furthermore, a greater individual APE was related to generally reduced depth of target processing as mirrored in smaller overall amplitudes of attention-sensitive target-related P1, P2, P300, and PSW. In addition, in the total sample P2, P300, and PSW were smaller for targets following AP eliciting, attention-capturing emotional, as compared to neutral primes. Based on the observed coincidence of increased processing of affective versus neutral primes, and specifically reduced processing of those targets that followed affective primes, we propose prime-target resource competition as an additional, not yet described process contributing to AP in the neutral-target paradigm.

Independent ERP predictors of affective priming underline the importance of depth of prime and target processing and implicit affect misattribution.

We used event-related potentials (ERPs) to investigate the mental processes that contribute to affective priming (AP), a systematic shift of evaluative judgments about neutral targets toward the valence of preceding primes. 64 participants rated their liking of a priori neutral ideographs preceded by 800-ms emotional primewords, while 64-channel EEG was recorded. We observed a significant AP effect that was closely associated with prime valence dependent variations of the right central-to-parieto-occipital positive slow wave (PSW) amplitude in the target ERP, providing evidence for implicit affect misattribution as one source of the effect. While deeper target processing mirrored in valence unspecific central-to-parieto-occipital target PSW amplitude was negatively associated with AP, deeper prime processing indicated by valence unspecific central-to-parieto-occipital prime PSW amplitude was positively related to AP. These depth of processing effects underline the importance of strategic processes in AP. In a stepwise linear regression analysis, the prime valence effect on right central-to-parieto-occipital target PSW indicating affect misattribution and the two valence-unspecific ERP indices of processing depth (central-to-parieto-occipital prime- and target PSW) were independent predictors of the size of the AP effect. Together they accounted for 60% of the variance. Furthermore, an explorative analysis provided first evidence for the relevance of early discrimination of prime valence for AP.

On ignoring words-exploring the neural signature of inhibition of affective words using ERPs.

In the present study event-related potentials were used to shed further light on the neural signatures of active inhibition of the (affective) content of written words. Intentional inhibition was implemented by simply asking participants (N = 32) to ignore single words that served as primes in an affective priming (AP) task. In AP, evaluations about a priori neutral targets typically tend to shift towards the valence of preceding primes, denoting an AP effect (APE). To create a plausible cover-context emphasizing the usefulness of word inhibition, participants were asked to avoid this shift, that is, to make unbiased target evaluations. Ignoring the prime words was suggested as the most efficient strategy to achieve this aim. Effective inhibition of the words' (affective) content, as suggested by a significant APE present for words processed without any further instruction, but not for ignored ones, affected multiple stages of processing. On the neuronal level, word inhibition was characterized by reduced early perceptual (left-lateralized word-specific N170), later attentional (parietal P300), and affective-semantic processing (reduced posterior semantic asymmetry). Furthermore, an additional recruitment of top-down inhibitory control processes, which was mirrored in increased amplitudes of medial-frontal negativity, showed to be critically involved in intentional word inhibition.

Food has the right of way: Evidence for prioritised processing of visual food stimuli irrespective of eating style.

Visual attention for food is likely to play an important role for overeating. The attentional bias for visual food stimuli was investigated with respect to self-reported restrained, external and emotional eating style. Using a Rapid Serial Visual Presentation task (N = 103), the effects of visual food stimuli in the context of the attentional blink were examined. Food targets enhanced the attentional blink when presented as first targets in a rapid stream of pictures and impaired the identification of preceding non-food targets in terms of a backward interference when presented as second targets. Task irrelevant food distractors interfered with the identification of subsequent non-food targets. The effects provide evidence for a prioritisation of food stimuli in the allocation of attentional resources. The attentional bias for food emerged as a universal phenomenon irrespective of personal eating style. Therefore, enhanced attention for visual food stimuli seems to play no direct causal role in eating styles associated with overeating.

Affective priming and cognitive load: Event-related potentials suggest an interplay of implicit affect misattribution and strategic inhibition.

Prior research suggests that the affective priming effect denoting prime-congruent evaluative judgments about neutral targets preceded by affective primes increases when the primes are processed less deeply. This has been taken as evidence for greater affect misattribution. However, no study so far has combined an experimental manipulation of the depth of prime processing with the benefits of ERPs. Forty-seven participants made like/dislike responses about Korean ideographs following 800-ms affective prime words while 64-channel EEG was recorded. In a randomized within-subject design, three levels of working-memory load were applied specifically during prime processing. Affective priming was significant for all loads and even tended to decrease over loads, although efficiency of the load manipulation was confirmed by reduced amplitudes of posterior attention-sensitive prime ERPs. Moreover, ERPs revealed greater explicit affective discrimination of the prime words as load increased, with strongest valence effects on central/centroparietal N400 and on the parietal/parietooccipital late positive complex under high load. This suggests that (a) participants by default tried to inhibit the processing of the prime's affect, and (b) inhibition more often failed under cognitive load, thus causing emotional breakthrough that resulted in a binding of affect to the prime and, hence, reduced affect misattribution to the target. As a correlate of affective priming in the target ERP, medial-frontal negativity, a well-established marker of (low) stimulus value, increased with increasing negative affect of the prime. Findings support implicit prime-target affect transfer as a major source of affective priming, but also point to the role of strategic top-down processes.