The Association Between Facial Width-to-Height Ratio (fWHR) and Sporting Performances: Evidence From Professional Basketball Players in Japan.

Previous research in evolutionary psychology has highlighted the potential role of facial structures in explaining human behavior. The facial width-to-height ratio (fWHR) was found to be associated with testosterone-driven behavioral tendencies like achievement drive, aggression, and sporting success. The current study aimed to replicate such relationships using real-world data (i.e., professional basketball players; N = 482). Achievement drive, aggression, and sporting success were operationalized as field-goal attempts (FGA), the number of fouls committed (Foul), and player performance rating (EFF), respectively. The results indicated that fWHR was significantly associated with FGA and EFF, controlling for minutes of play and body-mass-index. The same results were obtained for separate analyses focusing on outsider players. However, analyses of inside players demonstrated that fWHR was associated only with EFF. The current research further provides empirical evidence supporting the effects of fWHR on achievement drive and sporting successes, although the effect sizes are notably small.

Effect of polyphenols on 3-hydroxy-3-methylglutaryl-coenzyme A lyase activity in human hepatoma HepG2 cell extracts.

When carbohydrate metabolism is impaired, fatty acid metabolism is activated. Excess acetyl-coenzyme A (CoA) is generated from fatty acids by ß-oxidation and is used for the formation of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) and subsequently for acetoacetate. High levels of secreted ketone bodies (acetoacetate and 3ß-hydroxybutyrate) lower the pH of blood and urine, resulting in ketoacidosis. HMG-CoA lyase in hepatic cells is a rate-limiting enzyme catalyzing the cleavage of HMG-CoA to acetoacetate, and thus inhibition of this enzyme results in reduced acetoacetate production, in other words, impaired ketoacidosis. Inhibition of HMG-CoA lyase activity possibly prevents ketoacidosis and should be the therapeutic target. Polyphenols are common and abundant dietary constituents with beneficial effects on human health. We examined the inhibitory effects of dietary polyphenols on HMG-CoA lyase activity in cellular extracts of human hepatoma HepG2 cells. Of the nine representative dietary polyphenols tested, (-)-epigallocatechin (EGC), (-)-epigallocatechin gallate (EGCG), and gallic acid (GA) effectively inhibited HMG-CoA lyase activity. Lineweaver-Burk analysis revealed that EGC and EGCG are likely to be mixed-type noncompetitive inhibitors. Pyrogallol with the gallyl structure also inhibited HMG-CoA lyase activity, suggesting that the gallyl moiety of polyphenols is important for the inhibition of HMG-CoA lyase activity.