RESUMEN
The treatment results were compared in 77 patients with maxillary sinus squamous cell carcinoma (MC) and 53 patients with squamous cell carcinoma arising from the oral part of the upper jaw (OC). Both sets of patients received radiotherapy alone, or radiotherapy combined with surgery and/or chemotherapy. Computerized tomography was useful for the definition of the treatment volume. Intraarterial chemotherapy was given in 89 of 130 patients and in these patients the total radiation dose was reduced by about 10 Gy. No difference was found in the 5-year survival rate between the MC (65%) and the OC (66%) groups. The cumulative incidence of local failure was higher in MC (36%) than in OC (26%), whereas the ultimate incidence of neck node metastasis was higher in OC (43%) than in MC patients (18%). Half of the inoperable patients (9/18) were older than 80 years and had contraindications to anaesthesia and major surgery. The local recurrence rate was high in the inoperable MC patients (6/8). Contralateral sinus cancers occurred in 4 patients in the MC group.
Asunto(s)
Carcinoma de Células Escamosas/terapia , Neoplasias Maxilares/terapia , Neoplasias del Seno Maxilar/terapia , Anciano , Anciano de 80 o más Años , Antineoplásicos/administración & dosificación , Terapia Combinada , Femenino , Humanos , Infusiones Intraarteriales , Metástasis Linfática , Masculino , Neoplasias de la Boca/terapia , Recurrencia Local de Neoplasia , Dosificación RadioterapéuticaRESUMEN
The results of CT and bone scintigraphy of eight patients with a histologically proven cystic ameloblastoma of the jaw are reviewed. CT imaging revealed unilocular and multilocular cystic lesions with well-defined thin cystic borders in all patients. CT also detected increased density in the bone marrow adjacent to the cystic radiolucent lesion, suggesting that the ameloblastoma had spread into the cancellous bone. Further, nuclear bone scans showed a doughnut-shaped pattern in all cases and radioactivity beyond the cystic wall, indicating intramedullary extension of the ameloblastoma. The use of these two modalities was found to be complementary in delineating the full nature and extent of the pathologic lesion.
Asunto(s)
Ameloblastoma/diagnóstico por imagen , Neoplasias Maxilomandibulares/diagnóstico por imagen , Adulto , Difosfonatos , Femenino , Humanos , Maxilares/diagnóstico por imagen , Masculino , Cintigrafía , Compuestos de Tecnecio , Tomografía Computarizada por Rayos XRESUMEN
An analysis has been undertaken of 45 patients with non-metastatic squamous cell carcinoma of the buccal mucosa treated by permanent 198Au or 222Rn implants and in most cases supplementary external irradiation. Eight patients had T1, 30 had T2, and 7 T3 disease. Of the lesions 21 were located in the buccal mucosal surface, 14 in the retromolar region, and 10 in the bucco-alveolar sulci. Seven of the 45 (16%) died of the disease and the actuarial 5-year survival rate was 81%. No obvious differences were noted in survival rate between different stages of the disease or between different subsites of the primary lesion. There were 6 local recurrences occurring from 3 to 33 months after treatment, and only one of these was salvageable by further radiation therapy. Neck node metastasis occurred in 11 cases from 2 to 34 months after treatment, and 8 of these cases responded successfully to a radical neck dissection or radiotherapy.
