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1.
Comput Biol Med ; 174: 108399, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38615461

RESUMEN

Glaucoma is one of the leading cause of blindness worldwide. Individuals affected by glaucoma, including patients and their family members, frequently encounter a deficit in dependable support beyond the confines of clinical environments. Seeking advice via the internet can be a difficult task due to the vast amount of disorganized and unstructured material available on these sites, nevertheless. This research explores how Large Language Models (LLMs) can be leveraged to better serve medical research and benefit glaucoma patients. We introduce Xiaoqing, a Natural Language Processing (NLP) model specifically tailored for the glaucoma field, detailing its development and deployment. To evaluate its effectiveness, we conducted two forms of experiments: comparative and experiential. In the comparative analysis, we presented 22 glaucoma-related questions in simplified Chinese to three medical NLP models (Xiaoqing LLMs, HuaTuo, Ivy GPT) and two general models (ChatGPT-3.5 and ChatGPT-4), covering a range of topics from basic glaucoma knowledge to treatment, surgery, research, management standards, and patient lifestyle. Responses were assessed for informativeness and readability. The experiential experiment involved glaucoma patients and non-patients interacting with Xiaoqing, collecting and analyzing their questions and feedback on the same criteria. The findings demonstrated that Xiaoqing notably outperformed the other models in terms of informativeness and readability, suggesting that Xiaoqing is a significant advancement in the management and treatment of glaucoma in China. We also provide a Web-based version of Xiaoqing, allowing readers to directly experience its functionality. The Web-based Xiaoqing is available at https://qa.glaucoma-assistant.com//qa.


Asunto(s)
Glaucoma , Humanos , Glaucoma/tratamiento farmacológico , Glaucoma/fisiopatología , Procesamiento de Lenguaje Natural , Masculino , Femenino
2.
Comput Biol Med ; 165: 107344, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-37603961

RESUMEN

Medical record images in EHR system are users' privacy and an asset, and there is an urgent need to protect this data. Image steganography can offer a potential solution. A steganographic model for medical record images is therefore developed based on StegaStamp. In contrast to natural images, medical record images are document images, which can be very vulnerable to image cropping attacks. Therefore, we use text region segmentation and watermark region localization to combat the image cropping attack. The distortion network has been designed to take into account the distortion that can occur during the transmission of medical record images, making the model robust against communication induced distortions. In addition, based on StegaStamp, we innovatively introduced FISM as part of the loss function to reduce the ripple texture in the steganographic image. The experimental results show that the designed distortion network and the FISM loss function term can be well suited for the steganographic task of medical record images from the perspective of decoding accuracy and image quality.


Asunto(s)
Confidencialidad , Registros Médicos , Informática Médica
3.
Sensors (Basel) ; 22(13)2022 Jun 30.
Artículo en Inglés | MEDLINE | ID: mdl-35808442

RESUMEN

Three-dimensional (3-D) localization information, including elevation angle, azimuth angle, and range, is important for locating a single source with spherical wave-fronts. Aiming to reduce the high computational complexity of the classical 3-D multiple signal classification (3D-MUSIC) localization method, a novel low-complexity reduced-dimension MUSIC (RD-MUSIC) algorithm based on the sparse symmetric cross array (SSCA) is proposed in this article. The RD-MUSIC converts the 3-D exhaustive search into three one-dimensional (1-D) searches, where two of them are obtained by a two-stage reduced-dimension method to find the angles, and the remaining one is utilized to obtain the range. In addition, a detailed complexity analysis is provided. Simulation results demonstrate that the performance of the proposed algorithm is extremely close to that of the existing rank-reduced MUSIC (RARE-MUSIC) and 3D-MUSIC algorithms, whereas the complexity of the proposed method is significantly lower than that of the others, which is a big advantage in practice.

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