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1.
J Oral Sci ; 60(4): 574-578, 2018 Dec 27.
Artículo en Inglés | MEDLINE | ID: mdl-30429435

RESUMEN

To better understand the clinical features of mass lesions of the tongue, we retrospectively evaluated frequency, recurrence rate, and complications in 296 patients who had undergone surgery for such lesions. The diagnoses were fibroma (43.6%), mucous cyst (14.2%), papilloma (11.8%), hemangioma (7.8%), granuloma (6.4%), lipoma (1.4%), schwannoma (1.0%), ectopic tonsil (0.7%), and other (13.2%). Recurrence was noted in two patients (0.7%). Twenty-two patients (7.4%) developed surgical complications, including lingual nerve paralysis (6.4%), glossodynia (0.6%), and postoperative infection (0.3%). Lingual nerve paralysis was observed in the ventral portion (42.1%) of the tongue, apex (36.8%), lateral border (10.5%), and dorsum (10.5%). When all sites were considered together, there was no significant difference in the number of patients presenting with lingual nerve paralysis (P = 0.075). However, there were significant differences in lingual nerve paralysis at the lateral border (P < 0.05), apex (P < 0.05), and dorsum (P < 0.001) but not at the ventral portion (P > 0.05) in the size of the patients with versus without it which suggests that the risk of lingual nerve paralysis is higher at the ventral tongue, regardless of tumor size. These results shed light on the clinical features of mass lesions of the tongue.


Asunto(s)
Complicaciones Posoperatorias/epidemiología , Neoplasias de la Lengua/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia , Estudios Retrospectivos , Factores de Riesgo , Neoplasias de la Lengua/patología
2.
Gan To Kagaku Ryoho ; 42(1): 131-3, 2015 Jan.
Artículo en Japonés | MEDLINE | ID: mdl-25596696

RESUMEN

A case showing reinforcement of the action of warfarin and potassium in a patient administered S-1 is reported.The patient was a 71-year-old man with left upper gingival cancer.He had ventricular tachycardia (VT), hypertrophic cardiomyopathy, and a cerebellar infarction.He underwent a pacemaker implantation, and was administered warfarin.After the operation, in mid-March 2010, he was administered with S-1 and warfarin. However, the international normalized ratio of prothrombin time (PT-INR) increased to an extremely high level of 5.82, and S-1 and warfarin were stopped. They were re-administered at the end of April, and the PT-INR stabilized to approximately 2.


Asunto(s)
Anticoagulantes/uso terapéutico , Cardiomiopatía Hipertrófica/tratamiento farmacológico , Infarto Cerebral/tratamiento farmacológico , Neoplasias de la Boca/tratamiento farmacológico , Neoplasias de Células Escamosas/tratamiento farmacológico , Taquicardia Ventricular/tratamiento farmacológico , Warfarina/uso terapéutico , Anciano , Antimetabolitos Antineoplásicos/uso terapéutico , Cardiomiopatía Hipertrófica/complicaciones , Infarto Cerebral/complicaciones , Combinación de Medicamentos , Interacciones Farmacológicas , Humanos , Masculino , Neoplasias de la Boca/complicaciones , Neoplasias de Células Escamosas/complicaciones , Ácido Oxónico/uso terapéutico , Taquicardia Ventricular/complicaciones , Tegafur/uso terapéutico
3.
Artículo en Inglés | MEDLINE | ID: mdl-24725990

RESUMEN

OBJECTIVE: To clarify whether intraoral ultrasonography (I-US) is effective for predicting metastasis of tongue cancer to the cervical lymph nodes. STUDY DESIGN: Participants comprised 29 patients with tongue carcinoma classified as T1-T4 using the TNM staging system. All patients underwent I-US preoperatively. Postoperatively, resected specimens were evaluated histopathologically. RESULTS: I-US found that cases with invasive depth ≥3 mm had higher potential for cervical lymph node metastasis than those with invasive depth <3 mm (P < .05). No other significant relationships were identified between observations on I-US and cervical lymph node metastasis. Cases with histopathologic blood vessel infiltration or lymph duct infiltration had a significant difference in risk of cervical lymph node metastasis. CONCLUSIONS: I-US is useful for preoperatively assessing the invasive depth of tongue carcinoma. Furthermore, observations from I-US and invasive depth of the tumor allowed presumptive diagnosis with regard to cervical lymph node metastasis.


Asunto(s)
Neoplasias de la Lengua/diagnóstico por imagen , Neoplasias de la Lengua/patología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Metástasis Linfática/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Estadificación de Neoplasias , Valor Predictivo de las Pruebas , Ultrasonografía
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