Insect pests and natural enemies associated with lettuce Lactuca sativa L. (Asteraceae) in an aquaponics system.

Although food is produced in aquaponics systems worldwide, no information is available on the occurrence of insect pests and natural enemies in aquaponic lettuce, Lactuca sativa L. In this study, a survey was carried out in an aquaponic system combining lettuce with lambari, Astyanax altiparanae (Garutti & Briski), aiming to determine the insect pests and natural enemies associated with this system. We also determined the predominant insect species and the effect of meteorological factors on their populations. Insect abundance was estimated by visual sampling during 13 cultivation cycles, totaling 27 sampling dates. The meteorological factors considered were air temperature and relative humidity, and their effects were determined using the Pearson correlation. The thrips Frankliniella schultzei (Trybom) and Caliothrips phaseoli (Hood) and the aphid Aphis spiraecola (Patch) predominated. Ambient temperature and relative humidity were essential factors affecting C. phaseoli and F. schultzei. The natural enemies found on the lettuce plants were the thrips Franklinothrips vespiformis (Crawford) and Stomatothrips angustipennis (Hood) and the ladybugs Cycloneda sanguinea L., Eriopis connexa (Germar), and Hippodamia convergens (Guérin-Méneville). These results constitute the first step for a lettuce-integrated pest-management program in aquaponics systems.

Association between job lost and mental health outcomes during the COVID-19 pandemic and the role of food insecurity as mediator of this relationship.

This study aimed to evaluate the association between employment status and mental health, considering food insecurity as a mediator of this relation. A cross-sectional population-based study was conducted with adults (≥ 18 and < 60 years) during the COVID-19 outbreak in two cities from Southern Brazil. Employment status was categorized into working, not working, and lost job. The mental health outcomes evaluated were depressive symptoms, perceived stress, and sadness. Food insecurity was identified by the short-form version of the Brazilian Food Insecurity Scale. Adjusted analyses using Poisson regression were performed to assess the association between employment status and mental health. Mediation analysis was performed to investigate the direct and indirect effects of employment status on mental health outcomes. In total, 1,492 adults were analyzed. The not working status was associated with 53% and 74% higher odds of perceived stress and of sadness, respectively. Being dismissed during the pandemic increased the odds of depressive symptoms, perceived stress, and sadness by 68%, 123%, and 128%, respectively. Mediation analyses showed that food insecurity was an important mediator of the association between employment status and depressive symptoms and sadness, but not of perceived stress. The complexity of these results highlights economic and nutritional aspects involved in mental health outcomes.

Study protocol for assessment of the efficacy of calcium dobesilate versus placebo on SARS-CoV-2 viral load in outpatients with COVID-19 (CADOVID study): a randomised, placebo-controlled, double-blind, monocentric phase II trial.

INTRODUCTION: SARS-CoV-2 mainly infects respiratory endothelial cells, which is facilitated through its spike protein binding to heparan sulphate. Calcium dobesilate (CaD) is a well-established, widely available vasoactive and angioprotective drug interacting with heparan sulphate, with the potential to interfere with the uptake of SARS-CoV-2 by epithelial cells. The CADOVID trial aims to evaluate the efficacy and safety of CaD in reducing the SARS-CoV-2 viral load in non-hospitalised adult patients diagnosed with COVID-19, confirmed by a positive SARS-CoV-2 PCR, including its efficacy to reduce the impact of persistent COVID-19 symptoms. METHODS AND ANALYSIS: This is a randomised, placebo-controlled, double-blind, monocentric phase II trial. Enrolment began in July 2022. A total of 74 adult patients will be randomly allocated to the CaD arm or the placebo group with a 1:1 ratio, respectively. Participants in the intervention arm will receive two capsules of CaD 500 mg two times per day and the placebo arm will receive two matching capsules of mannitol 312.5 mg two times per day, with a treatment period of 7 days for both arms, followed by a 77-day observational period without treatment administration. Participants will be asked to complete secured online questionnaires using their personal smartphone or other electronic device. These include a COVID-19 questionnaire (assessing symptoms, temperature measurement, reporting of concomitant medication and adverse events), a COVID-19 persistent symptoms' questionnaire and the Short Form 12-Item (SF-12) survey. SARS-CoV-2 PCR testing will be performed on nasopharyngeal swabs collected on days 1, 4, 8 and 21. The primary endpoint is the reduction from baseline of SARS-CoV-2 viral load determined by RT-PCR at day 4. ETHICS AND DISSEMINATION: This trial has received approval by the Geneva Regional Research Ethics Committee (2022-00613) and Swissmedic (701339). Dissemination of results will be through presentations at scientific conferences and publication in scientific journals. TRIAL REGISTRATION NUMBER: NCT05305508; Clinicaltrials.gov; Swiss National Clinical Portal Registry (SNCTP 000004938).

Consumption of ultra-processed foods and mental health of pregnant women from the South of Brazil.

The objective of this study is to evaluate the association between the consumption of ultra-processed foods (UPF) and the mental health of pregnant women from the South of Brazil. This is a cross-sectional study carried out in Criciúma, Brazil, through face-to-face interviews, from April to December 2022. Pregnant women aged 18 or older who underwent prenatal care in the forty-eight basic health care units of the municipality and who were in their third trimester of pregnancy were included. High consumption of UPF was considered as six or more items or subgroups of UPF consumed on the day before the interview, using the Nova-UPF screener. The mental health variables were depressive symptoms, stress, sadness and anxiety. Crude and adjusted analyses were conducted using the Fisher's exact test and the Poisson regression with robust variance. In total, 428 pregnant women were studied; most of them were aged between 20 and 25 years and were white. Pregnant women who presented high consumption of UPF were 1·42-fold (95 % CI 1·06, 1·92) more likely to experience anxiety and presented a prevalence 56 % (95 % CI 1·18, 2·07) higher of stress when compared with those who did not present high consumption of UPF. The prevalence of depressive symptoms and feelings of sadness was 1·31-fold (95 % CI 1·08, 1·60) and 3·41-fold (95 % CI 1·77, 6·58) higher among those with high consumption of UPF, respectively. The results suggest that diet quality is associated with the mental health of pregnant women. Promoting joint actions focused on food and nutritional education, and mental health, for pregnant women, is necessary.

Association between job lost and mental health outcomes during the COVID-19 pandemic and the role of food insecurity as mediator of this relationship / Associação entre perda de emprego e desfechos de saúde mental durante a pandemia de COVID-19 e o papel da insegurança alimentar como mediadora dessa relação / Asociación entre la pérdida de empleo y los resultados de salud mental durante la pandemia de COVID-19 y el papel de la inseguridad alimentaria como mediador de esta relación

Abstract: This study aimed to evaluate the association between employment status and mental health, considering food insecurity as a mediator of this relation. A cross-sectional population-based study was conducted with adults (≥ 18 and < 60 years) during the COVID-19 outbreak in two cities from Southern Brazil. Employment status was categorized into working, not working, and lost job. The mental health outcomes evaluated were depressive symptoms, perceived stress, and sadness. Food insecurity was identified by the short-form version of the Brazilian Food Insecurity Scale. Adjusted analyses using Poisson regression were performed to assess the association between employment status and mental health. Mediation analysis was performed to investigate the direct and indirect effects of employment status on mental health outcomes. In total, 1,492 adults were analyzed. The not working status was associated with 53% and 74% higher odds of perceived stress and of sadness, respectively. Being dismissed during the pandemic increased the odds of depressive symptoms, perceived stress, and sadness by 68%, 123%, and 128%, respectively. Mediation analyses showed that food insecurity was an important mediator of the association between employment status and depressive symptoms and sadness, but not of perceived stress. The complexity of these results highlights economic and nutritional aspects involved in mental health outcomes.

Resumo: O objetivo foi avaliar a associação entre situação de trabalho e saúde mental e o papel da insegurança alimentar como mediadora dessa relação. Um estudo transversal de base populacional foi conduzido com adultos (≥ 18 e < 60 anos) durante o surto de COVID-19 em duas cidades do Sul do Brasil. A situação de trabalho foi categorizada em trabalhando, não trabalhando e perda do emprego. Os desfechos de saúde mental avaliados foram sintomas depressivos, percepção de estresse e sentimento de tristeza. A insegurança alimentar foi identificada pela versão reduzida da Escala Brasileira de Insegurança Alimentar. Análises ajustadas por regressão de Poisson foram realizadas para avaliar a associação entre situação de trabalho e saúde mental. A análise de mediação foi realizada para investigar os efeitos diretos e indiretos da situação de trabalho sobre os desfechos de saúde mental. No total, foram analisados 1.492 adultos. Não trabalhar associou-se a 53% mais chances de percepção de estresse e 74% maiores de tristeza. A perda do emprego aumentou as chances de sintomas depressivos, estresse percebido e sentimento de tristeza em 68%, 123% e 128%, respectivamente. As análises de mediação mostraram que a insegurança alimentar foi um importante mediador da associação entre situação de trabalho e sintomas depressivos e sentimento de tristeza, mas não para o estresse percebido. A complexidade desses resultados destaca aspectos econômicos e nutricionais envolvidos nos desfechos em saúde mental.

Resumen: El objetivo fue evaluar la asociación entre la situación laboral y la salud mental y el papel de la inseguridad alimentaria como mediador en esta relación. Se realizó un estudio transversal basado en la población con adultos (≥ 18 y < 60 años) durante el brote de COVID-19 en dos ciudades del Sur de Brasil. La situación laboral se clasificó en trabajando, no trabajando y pérdida de empleo. Los resultados de salud mental evaluados fueron síntomas depresivos, percepción de estrés y sensación de tristeza. La inseguridad alimentaria fue identificada por la versión reducida de la Escala Brasileña de Inseguridad Alimentaria. Se realizaron análisis ajustados por regresión de Poisson para evaluar la asociación entre la situación laboral y la salud mental. Se realizó un análisis de mediación para investigar los efectos directos e indirectos de la situación laboral en los resultados de salud mental. En total, se analizaron 1.492 adultos. No trabajar se asoció con un 53% más de probabilidades de percepción de estrés y un 74% más de probabilidades de tristeza. La pérdida del trabajo aumentó las probabilidades de síntomas depresivos, estrés percibido y sentimientos de tristeza en un 68%, 123% y 128%, respectivamente. Los análisis de mediación mostraron que la inseguridad alimentaria era un mediador importante de la asociación entre la situación laboral y los síntomas depresivos y los sentimientos de tristeza, pero no para el estrés percibido. La complejidad de estos resultados destaca los aspectos económicos y nutricionales que intervienen en los resultados de salud mental.

Use of a menthol popsicle in managing postoperative thirst in patients undergoing radical prostatectomy: A randomized clinical trial.

Background and aim: Thirst is a real bother that most patients feel in the immediate postoperative period when they still need to fast. Many approaches regarding symptomatic relief strategies have been described in the literature, but strategies with cold water and/or menthol are effective in quenching thirst, as they act on pre-absorptive mechanisms. This study aims to evaluate the effectiveness of using menthol popsicles in relieving postoperative thirst in patients undergoing radical prostatectomy. Material and methods: This is a randomized controlled clinical trial with a quantitative approach. In all, 44 patients were evaluated in the immediate postoperative period of radical prostatectomy, with the intensity and discomfort of thirst being evaluated initially and subsequently. The study consisted of two groups: (1) the placebo group, popsicles without the addition of menthol substrates and (2) the experimental group, popsicles with the addition of 0.05% minty substrates. Results: The results demonstrate that the sociodemographic and clinical characteristics were homogeneous at the α = 5% significance level, except the occupation variable. The test detected changes in the intensity and discomfort of thirst in relation to the pre- and post-intervention times for the primary outcome when the groups were analyzed separately and for the interaction of the group versus time, there was no statistical difference between the groups. Conclusion: It was possible to prove that both the menthol popsicle and the popsicle without the addition of menthol were effective in relieving postoperative thirst in patients undergoing radical prostatectomy, but there was no statistically significant difference when comparing the two groups. Trial registration: The Brazilian Registry of Clinical Trials (RBR-8c3chr7).

Strategies for thirst management in postoperative adult patients: a scoping review.

OBJECTIVES: to map the strategies for managing thirst in postoperative adult patients. METHODS: scoping review was conducted in October 2021 in 19 data sources: 14 databases and 5 platforms to search in the grey literature. It was prepared according to the recommendations of the Joanna Briggs Institute and the checklist of the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Nine selected articles were part of the final sample. RESULTS: there is evidence of strategies to manage postoperative thirst using interventions such as water, ice, mentholated measures, carbohydrate and protein enriched fluid, oral hydrator, flavored gargling, cold gargling, wet gauze, 0.75% citric acid spray, and cold water. FINAL CONSIDERATIONS: the strategies observed may be reduced to cold and menthol use, salivary stimulants, and early introduction of fluids. The outcomes were positive in all the studies reviewed.

Effectiveness of implementing an improvement cycle in the identification of critically ill patients.

OBJECTIVE: To evaluate the effectiveness of implementing a quality improvement cycle in the process for identifying critically ill patients in an intensive care center. METHODS: The implementation of an observational and interventional improvement cycle, using a before-and-after quasi-experimental design, with a quantitative approach, in an intensive care center. Seven criteria were developed to evaluate the quality of the identification process. The results of the intervention were subjected to statistical analysis. RESULTS: The quality of the identification process showed significant improvement in the values referring to compliance with the conformities in the criteria evaluated. Statistical significance was observed in the evaluations of criteria C1, C2, C3, C4, and C6, with increased compliance values after the intervention. FINAL CONSIDERATIONS: The efficacy of the improvement cycle in the quality of the patient identification process was evidenced. It was possible to involve and encourage the participation of the care team and improve organizational processes.

Fibromodulin Gene Variants (FMOD) as Potential Biomarkers for Prostate Cancer and Benign Prostatic Hyperplasia.

By the year 2050, the world's elderly population may increase exponentially, raising the rate of disease characteristic of this group, such as prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Prostate disorders have a multifactorial etiology, especially age and genetic factors. Currently, PCa is the second most frequent neoplasm in the male population worldwide. The fibromodulin gene encodes a small leucine-rich proteoglycan (SLRP) which acts in the collagen fibrillogenesis pathway, cell adhesion, and modulation of TGF-ß signaling pathways, which has been recently associated with PCa. The present study sequenced the coding region of the FMOD in a sample of 44 PCa, 90 BPH, and 82 controls from a Brazilian population, and the results identified 6 variants: 2 missenses (p.(Tyr42Ser) and p.(Pro24Ala)); 3 synonymous (p.(His253=), p.(Asn353=), and p.(Glu79=)); and 1 intronic (c.980-114A>G). Of these, p.(Tyr42Ser), p.(Pro24Ala), and p.(Asn353=) are rare variants, and p.(Tyr42Ser) was predicted as potential pathogenic by the algorithms used here, in addition to not being observed in controls, suggesting that may be a potential biomarker for development of PCa and BPH. In conclusion, we identified for the first time, in Brazilian individuals with PCa and BPH, a potentially pathogenic variant in the analysis of FMOD gene. Further studies are needed to investigate the deleterious effect of this variant on the structure and/or function of the FMOD protein.

Use of ginger to control nausea and vomiting caused by chemotherapy in patients with cervical cancer undergoing treatment: An experiment.

INTRODUCTION: Uterine cervix tumors have an invasive nature, with the capacity to proliferate to surrounding organs such as the vagina, bladder, and rectum, as well as the capacity for dissemination and involvement of structures distant from its place of origin. According to the International Federation of Gynecology and Obstetrics, patients with stages IB I, IB I microscopic (small dimension <4 cm) are indicated for radiotherapy or adjuvant chemoradiotherapy with cisplatin (40 mg/m2). However, cisplatin has side effects such as hematological implications (anemia, neutropenia, and thrombocytopenia), gastrointestinal disorders (nausea, vomiting, diarrhea, constipation), and fatigue. Zingiber officinale contains bioactive compounds that act on pregnancy and postoperative nausea, chemotherapy-induced nausea and vomiting, and also in the management of fatigue, myalgia, and insomnia. This study aimed to evaluate the effects of ginger on chemotherapy-induced nausea and vomiting in patients with cervical cancer undergoing treatment with cisplatin and radiotherapy. METHODS AND ANALYSES: A randomized intervention clinical and controlled trial with a triple-blind design is described, comparing the effects of institutional antiemetic therapy alone, as well as in combination with 2 different ginger concentrations. ETHICS AND DISSEMINATION: Due to the nature of the study, we obtained approval from the Division Ethics Committee of Liga Contra o Câncer. All participants signed an informed consent form prior to randomization. The results of this study will be published in peer-reviewed journals. The data collected will also be available in a public repository of data. TRIAL REGISTRATION NUMBER: This study is registered in the Brazilian Registry of Clinical Trials under number RBR-47yx6p9. This study was approved by the Division Ethics Committee of Liga Contra o Câncer under CAAE 40602320.0.0000.5293.

Strategies for thirst management in postoperative adult patients: a scoping review / Estrategias para el manejo de la sed de pacientes adultos en posoperatorio: revisión de ámbito / Estratégias para o manejo da sede de pacientes adultos em pós operatório: revisão de escopo

ABSTRACT Objectives: to map the strategies for managing thirst in postoperative adult patients. Methods: scoping review was conducted in October 2021 in 19 data sources: 14 databases and 5 platforms to search in the grey literature. It was prepared according to the recommendations of the Joanna Briggs Institute and the checklist of the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Nine selected articles were part of the final sample. Results: there is evidence of strategies to manage postoperative thirst using interventions such as water, ice, mentholated measures, carbohydrate and protein enriched fluid, oral hydrator, flavored gargling, cold gargling, wet gauze, 0.75% citric acid spray, and cold water. Final Considerations: the strategies observed may be reduced to cold and menthol use, salivary stimulants, and early introduction of fluids. The outcomes were positive in all the studies reviewed.

RESUMEN Objetivos: mapear estrategias para el manejo de la sed de pacientes adultos en posoperatorio. Métodos: revisión de ámbito realizada en octubre de 2021, en 19 fuentes de datos, siendo 14 bancos de datos y 5 plataformas para investigación de literatura gris. Fue elaborada conforme las recomendaciones del Instituto Joanna Briggs y del checklist del Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Fueron seleccionados nueve artículos para componer la muestra final del trabajo. Resultados: hay evidencias de estrategias para manejo de la sed posoperatoria utilizando intervenciones como: agua, hielo, medidas mentoladas, líquido enriquecido con carbohidrato y proteína, hidratante oral, gárgaras de olor, gárgaras frío, gasa húmeda, spray de ácido cítrico a 0,75% y agua fría. Consideraciones Finales: las estrategias vistas pueden ser resumidas en uso del frio y del mentol, estimulantes salivares e introducción precoz de líquidos. Los desfechos fueron positivos en todos los estudios elucidados.

RESUMO Objetivos: mapear as estratégias para o manejo da sede de pacientes adultos em pós-operatório. Métodos: revisão de escopo realizada em outubro de 2021, em 19 fontes de dados, sendo 14 bancos de dados e 5 plataformas para pesquisa de literatura cinzenta. Foi elaborada conforme as recomendações do Instituto Joanna Briggs e do checklist do Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Foram selecionados nove artigos para compor a amostra final do trabalho. Resultados: há evidências de estratégias para manejo da sede pós-operatória utilizando intervenções como: água, gelo, medidas mentoladas, líquido enriquecido com carboidrato e proteína, hidratante oral, gargarejo de aroma, gargarejo frio, gaze úmida, spray de ácido cítrico a 0,75% e água fria. Considerações Finais: as estratégias vistas podem ser resumidas em uso do frio e do mentol, estimulantes salivares e introdução precoce de líquidos. Os desfechos foram positivos em todos os estudos elucidados.

Effectiveness of implementing an improvement cycle in the identification of critically ill patients / Efectividad de la implantación de un ciclo de mejoría en la identificación del paciente crítico / Efetividade da implantação de um ciclo de melhoria na identificação do paciente crítico

ABSTRACT Objective: To evaluate the effectiveness of implementing a quality improvement cycle in the process for identifying critically ill patients in an intensive care center. Methods: The implementation of an observational and interventional improvement cycle, using a before-and-after quasi-experimental design, with a quantitative approach, in an intensive care center. Seven criteria were developed to evaluate the quality of the identification process. The results of the intervention were subjected to statistical analysis. Results: The quality of the identification process showed significant improvement in the values referring to compliance with the conformities in the criteria evaluated. Statistical significance was observed in the evaluations of criteria C1, C2, C3, C4, and C6, with increased compliance values after the intervention. Final considerations: The efficacy of the improvement cycle in the quality of the patient identification process was evidenced. It was possible to involve and encourage the participation of the care team and improve organizational processes.

RESUMEN Objetivo: Evaluar efectividad de implantación de un ciclo de mejoría de calidad en el proceso de identificación del paciente crítico en un centro de cuidados intensivos. Métodos: Implementación de ciclo de mejoría, observacional e intervención, utilizando diseño cuasi-experimental, antes y después, con abordaje cuantitativo, en un centro de cuidados intensivos. Elaborados siete criterios para evaluación de calidad del proceso de identificación. Los resultados de la intervención fueron sometidos al análisis estadístico. Resultados: La calidad del proceso de identificación presentó mejoría significativa en los valores referentes al cumplimiento de las conformidades en los criterios evaluados. Observada significación estadística en las evaluaciones de los criterios C1, C2, C3, C4 y C6, con aumento en los valores de cumplimiento posintervención. Consideraciones finales: Evidenciado la eficacia del ciclo de mejoría en la calidad del proceso de identificación del paciente. Fue posible involucrar y estimular la participación del equipo asistencial y mejorar los procesos organizacionales.

RESUMO Objetivo: Avaliar a efetividade da implantação de um ciclo de melhoria da qualidade no processo de identificação do paciente crítico em um centro de cuidados intensivos. Métodos: Trata-se da implementação de ciclo de melhoria, observacional e de intervenção, utilizando desenho quase experimental, antes e depois, com abordagem quantitativa, em um centro de cuidados intensivos. Foram elaborados sete critérios para avaliação da qualidade do processo de identificação. Os resultados da intervenção foram submetidos à análise estatística. Resultados: A qualidade do processo de identificação apresentou melhoria significativa nos valores referentes ao cumprimento das conformidades nos critérios avaliados. Foi observada significância estatística nas avaliações dos critérios C1, C2, C3, C4 e C6, com aumento nos valores de cumprimento após a intervenção. Considerações finais: Evidenciou-se a eficácia do ciclo de melhoria na qualidade do processo de identificação do paciente. Foi possível envolver e estimular a participação da equipe assistencial e melhorar os processos organizacionais.

Mesenteric metastasis of granulosa cell tumor in a bitch: a case report / Metástasis mesentérica de tumor de células de granulosa en una perra: reporte de caso / Metástase mesentérica de tumor das células da granulosa em uma cadela: relato de caso

Abstract Anamnesis: A 5-year-old mixed breed entire bitch was presented with bloody vaginal discharge and abdominal distension. Clinical and laboratory findings: Physical examination and abdominal ultrasonography suggested the presence of a left ovarian tumor. At histopathological examination it was diagnosed as granulosa cell tumor. Treatment approach: An exploratory laparotomy was performed followed by ovariohysterectomy to remove the intra-abdominal mass. Conclusion: The clinical, ultrasonographic and histologic signs in this case support other literature reports. Ultrasonography, in combination with histopathologic analysis is a fundamental tool for detection of ovarian tumors, especially tumors of the granulosa cells.

Resumen Anamnesis: Una perra entera sin raza definida, con cinco años de edad, presentando secreción vaginal sanguinolenta con una distensión abdominal acentuada. Hallazgos clínicos y de laboratorio: El examen clínico y la ultrasonografía abdominal sugirieron la presencia de la neoformación ovárica izquierda. En el examen histopatológico fue diagnosticado como tumor de células de la granulosa. Aproximación terapéutica: Se realizó una laparotomía exploratoria seguida de ovariohisterectomía para eliminar la masa intra-abdominal. Conclusión: Los signos clínicos, ecográficos e histológicos en este caso respaldan otros informes de la literatura. La ecografía, en combinación con el análisis histopatológico, es una herramienta fundamental para la detección de tumores ováricos, especialmente tumores de las células de la granulosa.

Resumo Anamnese: Uma cadela sem raça definida, com cinco anos de idade, não castrada, apresentando secreção vaginal sanguinolenta com acentuada distensão abdominal. Achados clínicos e laboratoriais: O exame clínico e ultrassonografia abdominal sugeriram a presença de neoformação ovariana esquerda. No exame histopatológico foi diagnosticado como tumor de células da granulosa. Abordagem terapêutica: Foi realizada laparotomia exploratória seguida de ovariohisterectomia para remoção da massa intra-abdominal. Conclusão: Os sinais clínicos, ultrassonográficos e histológicos corroboram a literatura, concluindo que a modalidade ultrassonográfica, em associação a análise histopatológica é uma ferramenta fundamental na detecção de neoformações ovarianas, contribuindo significativamente no diagnóstico final.

Epidemiologia das vítimas de trauma atendidas por serviço pré-hospitalar / Epidemiology of trauma victims served by prehospital service / Epidemiología de las víctimas de trauma atendidas por servicio prehospitalario

Objetivo: caracterizar os aspectos epidemiológicos das vitimas de trauma atendidas por um Serviço de Atendimento Móvel de Urgência 192. Método: estudo exploratório, descritivo e quantitativo, realizado no pronto socorro de um hospital de referencia. A população alvo foram as vitimas de trauma atendidas pelo Serviço de Atendimento Móvel de Urgência, transportadas para o referido hospital. Resultados: observou-se que 5,9% deram entrada na urgência por Ferimentos por Arma de Fogo, 4,9% por Ferimento por Arma Branca, 23,8% por queda, e 60,4% por acidentes de transito. Conclusão: o perfil identificado foi de homens, vitimas de acidente de transito, nas idades de 18 a 35 anos, com segundo grau completo, sendo o tórax a região mais atingida. Esse estudo pode subsidiar a elaboração de estratégias para enfrentamento desses agravos, pois a grande quantidade de óbitos por causas externas são considerados um problema de saúde publica, causando sequelas irreparáveis

Objective: to characterize the epidemiological aspects of the victims of trauma treated by a Mobile Emergency Care Service 192. Method: an exploratory, descriptive and quantitative study, carried out in the first aid hospital of a reference hospital. The target population was the victims of trauma treated by the Mobile Emergency Care Service, transported to the referred hospital. Results: It was observed that 5.9% were admitted to the emergency due to Firearm Injuries, 4.9% to White Weapon Injury, 23.8% to fall, and 60.4% due to trafficaccidents. Conclusion: the identified profile was of men, victims of traffic accident, in the ages of 18 to 35 years, with full second degree, being the thorax the most affected region. This study may support the development of strategies to deal with these diseases, since the large number of deaths from external causes are considered a public health problem, causing irreparable sequelae

Objetivo: caracterizar los aspectos epidemiologicos de las victimas de trauma atendidas por un Servicio de Atencion Movil de Urgencia 192. Método: estudio exploratorio, descriptivo y cuantitativo, realizado en el pronto socorro de un hospital de referencia. La poblacion objetivo fueron las victimas de trauma atendidas por el Servicio de Atencion Movil de Urgencia, transportadas al referido hospital. Resultados: se observo que el 5,9% ingreso en la urgencia por Feridas por Arma de Fuego, 4,9% por Lesion por Arma Blanca, 23,8% por caida, y 60,4% por accidentes de transito. Conclusión: el perfil identificado fue de hombres, victimas de accidente de transito, en las edades de 18 a 35 anos, con segundo grado completo, siendo el torax la region mas afectada. Este estudio puede subsidiar la elaboracion de estrategias para enfrentar esos agravios, pues la gran cantidad de muertes por causas externas son consideradas um problema de salud publica, causando secuelas irreparables

Implementação de ciclo de melhoria nos registros em prontuários hospitalares: um estudo quase experimental

RESUMO Objetivo: Implantar e avaliar um programa de melhoria dos registros em prontuários do um hospital do município de Farias Brito, estado do Ceará, Brasil. Material e Método: Trata-se de um estudo com abordagem quantitativa, quase experimental do tipo antes e depois de avaliação de critérios de qualidade. A pesquisa foi realizada entre janeiro de 2017 e julho de 2018. Foram avaliados 87 registros em prontuários selecionados de forma aleatória, realizados pela equipe multiprofissional totalizando 35 profissionais. Foi realizado em seis etapas: 1) Identificação e priorização de um problema de qualidade, 2) Análise das causas do problema, 3) Desenvolvimento de critérios para avaliar o nível de qualidade, 4) Avaliação do nível de qualidade, 5) Intervenção de melhoria dirigida aos critérios mais problemáticos e 6) Reavaliação do nível de qualidade. Para avaliar a qualidade, antes e depois da intervenção, foi realizado cálculo da estimativa pontual e do intervalo de confiança (IC= 95%) do nível de cumprimento de oito critérios. Para avaliar o efeito da intervenção, foi estimada melhoria absoluta e relativa de cada teste de hipótese unilateral por meio do cálculo do valor de Z. No ciclo de melhoria, os dados foram analisados pelo Gráfico de Pareto. Resultados: Na medição inicial, foram obtidos índices de cumprimento de 36,30% em média, enquanto na segunda medição, notou-se um aumento na média de cumprimentos de todos os critérios em 19,45%. Conclusão: Percebe-se que o ciclo de melhoria é uma ferramenta efetiva para fortalecer a qualidade dos serviços desenvolvidos especialmente a qualidade dos registros em prontuários do hospital.

ABSTRACT Objective: To implement and evaluate a program to improve medical records in a hospital located in the municipality of Farias Brito, Ceará State, Brazil. Material and Method: Quasi-experimental study of the type before and after the evaluation of quality criteria, with a quantitative approach. The survey was conducted between January 2017 and July 2018. 87 records were evaluated in randomly selected medical records that had been performed by the multi-professional team consisting of 35 professionals. The research was carried out in six steps: 1) Identification and prioritization of a quality problem, 2) Analysis of the causes of the problem, 3) Development of criteria to evaluate the quality level, 4) Evaluation of the quality level, 5) Improvement intervention aimed at the most problematic criteria, and 6) Re-evaluation of the quality level. To assess quality before and after the intervention, point estimation and confidence interval (CI= 95%) of the level of compliance to eight criteria was calculated. To evaluate the effect of the intervention, absolute and relative improvement of each one-sided hypothesis test was estimated by calculating the Z-score. In the improvement cycle, data were analyzed using Pareto chart. Results: In the first measurement, compliance rates of 36.30% on average were obtained, while in the second measurement there was an increase in the average level of compliance of all criteria by 19.45%. Conclusion: It is clear that the improvement cycle is an effective tool to strengthen the quality of the hospital services, especially when related to quality of patient's medical records.

RESUMEN Objetivo: Implementar y evaluar un programa para mejorar los registros en la historia clínica de un hospital del município de Farias Brito, estado de Ceará, Brasil. Material y Método: Estudio con enfoque cuantitativo, cuasi-experimental del tipo antes y después de la evaluación de criterios de calidad. La encuesta se realizó entre enero de 2017 y julio de 2018. Se evaluaron 87 registros de historias clínicas, seleccionados al azar, realizados por el equipo multiprofesional, totalizando 35 profesionales. Se llevó a cabo en seis pasos: 1) Identificación y priorización de un problema de calidad, 2) Análisis de las causas del problema, 3) Desarrollo de criterios para evaluar el nivel de calidad, 4) Evaluación del nivel de calidad, 5 ) Intervención de mejora dirigida a los criterios más problemáticos y 6) Reevaluación del nivel de calidad. Para evaluar la calidad, antes y después de la intervención, se calculó la estimación puntual y el intervalo de confianza (IC = 95%) del nivel de cumplimiento de ocho criterios. Para evaluar el efecto de la intervención, se estimó la mejora absoluta y relativa de cada prueba de hipótesis unilateral mediante el cálculo del valor Z. En el ciclo de mejora, los datos se analizaron mediante el diagrama de Pareto. Resultados: En la medición inicial se obtuvieron tasas de cumplimiento de 36,30% en promedio, mientras que en la segunda medición hubo un aumento en el promedio de cumplimiento de todos los criterios en 19,45%. Conclusión: Se observa que el ciclo de mejora es una herramienta eficaz para fortalecer la calidad de los servicios desarrollados, especialmente la calidad de los registros en la Historia clínica de los pacientes.

Impact of COVID-19 in patients with cancer: a scoping review / Impacto del COVID-19 en pacientes com cáncer: revisión de alcance / Impacto da COVID-19 em pacientes oncológicos: scoping review

ABSTRACT Objective: to map the knowledge about SARS-CoV-2 infection in patients with cancer in terms of clinical manifestations, treatment, and prognosis. Method: a scoping review based on the Joanna Briggs Institute theoretical framework, registered in the Open Science Framework (osf.io/64ems/). A search was carried out in nine databases and virtual libraries in June and July 2020. Results: twenty-five articles were selected that answered the guiding question, demonstrating that the neoplasm most affected by the infection was the lung, and the main clinical manifestations were fever, cough, dyspnea, diarrhea, and fatigue. Regarding treatment, antivirals and antibiotics were the most mentioned. All articles cite the vulnerability of patients with cancer diagnosed with COVID-19, with a mortality rate of 21-30% in most articles and a prognosis for progression to severe forms of the disease. Still, most patients were cured, although in severe cases they worsened, compared to the general population. Conclusion: this study demonstrated insecurity in disease treatment due to the variety of medications used and the uncertainty about whether to continue neoplastic treatment during this period.

RESUMEN Objetivo: mapear el conocimiento sobre la infección por SARS-CoV-2 en pacientes con cáncer, en términos de manifestaciones clínicas, tratamiento y pronóstico. Método: revisión del alcance, basada en el marco teórico del Instituto Joanna Briggs, registrado en el Open Science Framework (osf.io/64ems/). Se realizó una búsqueda en nueve bases de datos y bibliotecas virtuales, en los meses de junio y julio de 2020. Resultados: se seleccionaron 25 estudios que respondieron a la pregunta orientadora, demostrando que la neoplasia más afectada por la infección fue la pulmonar, y las principales manifestaciones clínicas fueron fiebre, tos, disnea, diarrea y fatiga. En cuanto al tratamiento, los antivirales y los antibióticos fueron los más mencionados. Todos los estudios citan la vulnerabilidad de los pacientes con cáncer diagnosticados con COVID-19, con una tasa de mortalidad del 21-30% en la mayoría de los estudios y un pronóstico de progresión a formas graves de la enfermedad. Aún así, la mayoría de los pacientes evolucionaron para curarse, aunque en los casos graves la evolución fue de peor pronóstico, en comparación con la población general. Conclusión: este estudio demostró inseguridad en el tratamiento de la enfermedad debido a la variedad de medicamentos utilizados y la incertidumbre sobre si continuar el tratamiento neoplásico durante este período.

RESUMO Objetivo: mapear o conhecimento sobre a infecção pelo SARS-CoV-2 em pacientes oncológicos, em termos de manifestações clínicas, tratamento e prognóstico. Método: revisão de escopo, com base no referencial teórico do Joanna Briggs Institute, registrada na Open Science Framework (osf.io/64ems/). Realizou-se busca em nove bases de dados e bibliotecas virtuais, nos meses de junho e julho de 2020. Resultados: selecionaram-se 25 estudos que respondiam à questão norteadora, demonstrando que a neoplasia mais acometida pela infecção foi a pulmonar, e as principais manifestações clínicas foram a febre, tosse, dispneia, diarreia e fadiga. No que fala sobre tratamento, os antivirais e antibióticos foram os mais mencionados. Todos os estudos citam a vulnerabilidade de pacientes oncológicos diagnosticados com COVID-19, com uma mortalidade de 21-30% na maioria dos estudos e um prognóstico de evolução para formas graves da doença. Ainda, a maioria dos pacientes evoluiu para a cura, embora nos casos graves a evolução tenha sido para o pior prognóstico, se comparado com a população em geral. Conclusão: este estudo demonstrou a insegurança no tratamento da doença pela variedade de medicamentos utilizados e a incerteza em continuar ou não o tratamento neoplásico neste período.

Efeito agudo do alongamento estático sobre o desempenho e atividade eletromiográfica da musculatura antagonista / Acute effect of static stretching on the performance and electromyographic activities of the antagonist muscles

RESUMO O objetivo foi verificar o efeito agudo do alongamento estático (AE) dos músculos Ísquiotibiais sobre o desempenho da força e ativação mioelétrica (EMGRMS) da musculatura antagonista. Doze homens (20,28 ± 1,50 anos; 83,35 ± 17,86 Kg; 177,28 ± 9,64 cm) experientes em treinamento de força foram divididos aleatoriamente nos grupos AE e controle (GC). No AE foram realizadas três repetições de 30s de alongamento estático nos Ísquiotibiais e em seguida foi medida a amplitude de movimento (ADM). Logo após, foi medido o desempenho da força e EMGRMS dos músculos vasto lateral (VL) e vasto medial (VM) durante o teste de 10-RM na cadeira extensora. A ANOVA de duas entradas encontrou diferença significativa na ADM no efeito principal tempo (P = 0,019), quanto para interação grupo x tempo (P = 0,023), com aumento significativo na ADM após o alongamento (P = 0,013). O número de repetições do AL aumentou significativamente (P = 0,014; 16%) em relação ao GC. Não houve mudança significativa no EMGRMS de nenhum dos músculos testados. O emprego do alongamento estático pode melhorar o desempenho da força na musculatura antagonista.

ABSTRACT The present study aimed to verify the acute effect of static stretching (SS) of the hamstrings muscles on the mioletric activation (EMGRMS) and strength performance of the antagonist muscle. Twelve men (20.28 ± 1.50 years, 83.35 ± 17.86 kg, 177.28 ± 9.64 cm) experienced in strength training were randomly divided into SS and control groups (GC). For the SS, three repetitions of 30s of static stretching were performed on the hamstrings and then the range of motion (ROM) was assessed. Subsequently, the strength performance and EMGRMS of the vastus lateralis (VL) and vastus medialis (MV) were assessed during the 10-RM test in the extensor chair. The twoway ANOVA found a significant difference in ROM for the main time effect (P = 0.019) and for group x time interaction (P = 0.023), with a significant increase in ROM after stretching (P = 0.013). The number of repetitions ater stretching increased significantly (P = 0.014; 16%) compared to the CG. There was no significant change in EMGRMS os the assessed muscles. The use of static stretching can improve the strength performance of the antagonist musculature.

Prevalence and Factors Associated with High Concentration of Prostate-Specific Antigen: ELSIA Study.

BACKGROUND: Prostate cancer (PC) is the second most common cancer among men, behind only non-melanoma skin cancer, and the main method of screening for PC is the prostate-specific antigen (PSA). To analyze the prevalence and the factors associated with high concentration of PSA in the elderly is essential to understand this outcome, and building strategies to decrease their rates of morbidity and mortality. METHODS: We performed a cross-sectional study with 96 elderly men. A high level of PSA was defined by >4.0 ng/mL. In order to identify sociodemographic, health, functional and behavioral variables, which may be associated with high levels of PSA, we carried out a multivariate analysis using Poisson regression. RESULTS: The prevalence of high levels of PSA was 21.9% (n = 21). High levels of PSA was associated with years of study, race/ethnicity and family arrangement, health perception, systolic blood pressure, diastolic blood pressure, metabolic diseases, alcohol consumption and sedentary behavior. CONCLUSIONS: The study found a high prevalence of high PSA concentrations in the elderly and several aspects are associated, which can be a worrying factor for their health, since PSA is an important marker of prostate cancer.

Implementation of improvement cycle in health records of mobile emergency prehospital care.

OBJECTIVE: to evaluate the effect of the implementation of a quality improvement cycle in the completion of occurrence forms of a Mobile Emergency Service. METHODS: this is a time series, quantitative, quasi-experimental study without control group, with three quality assessments in which was used an improvement cycle for adequacy of health records in Mobile Emergency Service Patos. RESULTS: in 100% of the seven criteria, there was improvement between evaluations. Noncompliance with criteria reduced from 95 cases in the first evaluation to eight cases in the third evaluation. CONCLUSIONS: the representation of joint results between the three evaluations highlighted progressive improvement in the compliance with each criterion.

Aspectos epidemiológicos, clínicos e angiográficos de pacientes submetidos à Intervenção Coronária Percutânea primária / Epidemiological, clinical and angiographic aspects of patients submitted to primary Percutaneous Coronary Intervention

Introduction: Having the profile of patients undergoing angioplasty helps to improve their quality of life and assist the health team. Objective: to analyze the epidemiological, clinical, and angiographic aspects and their relationship with the gender of patients undergoing primary percutaneous coronary intervention. Method: this is a descriptive and cross-sectional study carried out at a University Hospital in Rio Grande do Norte. Data collection took place between April and October 2017 from data found in the computerized and printed medical records of 93 patients undergoing Primary Percutaneous Coronary Intervention. Tests such as Kolmogorov-Sminorv, Mann-Whitney (U), and Pearson's chi-square (X2) evaluated the information evidenced by the research. Results: 64.5% of the 93 patients included in the study were men, with a mean age of 62.3 years old. Regarding the door-to-balloon time, 18.2% of women and 8.3% of men had time less than 90 minutes. The comorbidities of systemic arterial hypertension, diabetes mellitus, and alcoholism stand out. Conclusion: the results on the epidemiological, clinical, and angiographic aspects evidenced in this study favor greater knowledge, contributing to the generation of strategies for the prevention of diseases of patients submitted to primary Percutaneous Coronary Intervention.

Introdução: Dispor do perfil de pacientes submetidos à angioplastia colabora para a melhoria da qualidade de vida dos mesmos e trabalho assistencial da equipe de saúde. Objetivo: analisar os aspectos epidemiológicos, clínicos e angiográficos e suas relações com o sexo dos pacientes submetidos à intervenção coronária percutânea primária. Método: estudo descritivo e transversal realizado em Hospital Universitário do Rio Grande do Norte. A coleta de dados ocorreu entre abril e outubro de 2017 a partir de dados encontrados no prontuário informatizado e impresso de 93 pacientes submetidos à Intervenção Coronária Percutânea Primária. Utilizaram-se testes como o Kolmogorov-Sminorv, Mann-Whitney (U) e Qui-quadrado de Pearson (X2) para a avaliação das informações evidenciadas pela pesquisa. Resultados: dos 93 pacientes inclusos no estudo, 64,5% eram homens, com média de idade de 62,3 anos. Sobre o tempo porta-balão,18,2% das mulheres e 8,3% dos homens conseguiram o tempo menor que 90 minutos. Quanto às comorbidades, destacam-se Hipertensão Arterial Sistêmica, diabetes mellitus, além do hábito de vida etilismo. Conclusão: os resultados sobre os aspectos epidemiológicos, clínicos e angiográficos evidenciados neste estudo favorecem um maior conhecimento, contribuindo para a geração de estratégias para a prevenção de agravos de pacientes submetidos à Intervenção Coronária Percutânea Primária.