Effect of herbal mouthrinsein dental ultrasonic scalers among Indians.

The use of herbal mouthrinse is gaining momentum in recent years. Therefore, it is of interest to evaluate the effect of 2 herbal mouthrinse (curcumin, cinnamon) in comparison with2 conventional mouthrinse (povidone iodine, chlorhexidine) when used as coolant in dental ultrasonic scalers. Hence, 200 participants were included in this study. Analysis of gingival index, periodontal index at baseline and one month follow up was completed. The inhibitory effects of both conventional and herbal mouth rinse in gingival health are similar. However, cinnamon and curcumin owing to its minimal adverse effects and low cost is useful as an alternative to chlorhexidine for reducing bacterial load in dental aerosols produced due to ultrasonic scalers.

Artificial Intelligence's Use in the Diagnosis of Mouth Ulcers: A Systematic Review.

Artificial intelligence (AI) has been cited as being helpful in the diagnosis of diseases, the prediction of prognoses, and the development of patient-specific therapeutic strategies. AI can help dentists, in particular, when they need to make important judgments quickly. It can eliminate human mistakes in making decisions, resulting in superior and consistent medical treatment while lowering the workload on dentists. The existing studies relevant to the study and application of AI in the diagnosis of various forms of mouth ulcers are reviewed in this work. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards were followed in the preparation of the review. There were no rule violations, with the significant exception of the use of a better search method that led to more accurate findings. Using search terms mainly such as AI, oral health, oral ulcers, oral herpes simplex, oral lichen planus, pemphigus vulgaris, recurrent aphthous ulcer (RAU), oral cancer, premalignant and malignant disorders, etc., a comprehensive search was carried out in the reliable sources of literature, namely PubMed, Scopus, Embase, Web of Science, Ovid, Global Health, and PsycINFO. For all papers, exhaustive searches were done using inclusion criteria as well as exclusion criteria between June 28, 2018, and June 28, 2023. An AI framework for the automatic categorization of oral ulcers from oral clinical photographs was developed by the authors, and it performed satisfactorily. The newly designed AI model works better than the current convolutional neural network image categorization techniques and shows a fair level of precision in the classification of oral ulcers. However, despite being useful for identifying oral ulcers, the suggested technique needs a broader set of data for validation and training purposes before being used in clinical settings. Automated OCSCC identification using a deep learning-based technique is a quick, harmless, affordable, and practical approach to evaluating the effectiveness of cancer treatment. The categorization and identification of RAU lesions through the use of non-intrusive oral pictures using the previously developed ResNet50 and YOLOV algorithms demonstrated better accuracy as well as adequate potential for the future, which could be helpful in clinical practice. Moreover, the most reliable projections for the likelihood of the presence or absence of RAU were made by the optimized neural network. The authors also discovered variables associated with RAU that might be used as input information to build artificial neural networks that anticipate RAU.

Association Between Internet Use, Sleep, Cognition and Physical Activity Levels During COVID-19 Lockdown.

Purpose: The purpose of this study was to compare internet usage, sleep, cognition and physical activity in college professors and collegiate students during COVID-19 lockdown and to study the association of internet overuse with sleep quality, cognition and physical activity during the COVID-19 lockdown. Methods: A sample of 125 participants {professors (n = 52) and collegiate students (n = 73)} was recruited from Jamia Hamdard, New Delhi, India. Criteria for inclusion were college professors and collegiate students who uses internet. Both the groups were assessed for internet usage (Internet Addiction Test), sleep quality (Pittsburgh Sleep Quality Index), cognition (Cognitive Failure Questionnaire) and physical activity (Global Physical Activity Questionnaire) via google forms. Results: There was a significant difference for internet usage (p < 0.05), sleep quality (p = 0.032), cognition (distractibility, p = 0.019) and physical activity in college professors and collegiate students. It has been also reported that there was a significant association of internet usage with sleep quality and cognition and sleep quality with cognition. Conclusion: Students have more problematic internet usage, bad sleep quality, more cognitive failures and less physical activity than college professors during pandemic lockdown. It has been also observed that problematic internet usage has correlation with sleep quality, cognition and physical activity.

Artificial intelligence in oral health surveillance among under-served communities.

A sizable percentage of the population in India still does not have easy access to dental facilities. Therefore, it is of interest to document the role of artificial intelligence (AI) in oral surveillance of underserved communities. Available data shows that AI makes it possible to screen, diagnose, track, prioritize, and monitor dental patients remotely via smart devices. As a result, dentists won't have to deal with simple situations that only require standard treatments; freeing them up to focus on more complicated cases. Additionally, this would allow dentists to reach a broader, more underprivileged population in difficult-to-reach places. AI fracture recognition and categorization performance has shown promise in preliminary testing. Methods for detecting aberrations are frequently employed in public health practise and research continues to be focused on them.

Salt-Induced Dissolution of Protein Aggregates.

Protein aggregation is mediated by a complex interplay of noncovalent interactions and is associated with a broad range of aspects from debilitating human diseases to the food industry and therapeutic biotechnology. Deciphering the intricate roles of noncovalent interactions is of paramount importance for the design of effective inhibitory and disaggregation strategies, which remains a formidable challenge. By using a combination of spectroscopic and microscopic tools, here we show that the surfactant-mediated protein aggregation can be modulated by an intriguing interplay of hydrophobic and electrostatic effects. Additionally, our results illuminate the unique role of salt as a potent disaggregation inducer that alters the protein-surfactant electrostatic interactions and triggers the dissolution of preformed protein aggregates resulting in restoring the native protein structure. This unusual salt-induced dissolution and refolding offers a unique approach to regulating the balance between protein self-assembly and disassembly and will offer a potent strategy to design electrostatically targeted inhibitors.

Type 2 Diabetes Mellitus Patients Manifest Greater Muscle Fatigability Than Healthy Individuals During Dynamic Fatigue Protocol.

OBJECTIVE: The present study aimed to investigate the electromyographic (EMG) indices of muscle fatigue along with biochemical marker of fatigue-that is, blood lactate-during a dynamic fatigue protocol in individuals with type 2 diabetes mellitus (T2DM) vs a healthy control group. Secondarily, it aimed to examine the association between EMG indices of muscle fatigue and blood lactate in these patients. METHODS: Thirty-four participants took part in the study: 19 individuals with T2DM (age, 53.5 ± 6.85 years) and 15 age-matched healthy controls (age, 50.2 ± 3.55 years). Participants performed a dynamic fatigue protocol consisting of 5 sets of 10 repetitions each at an intensity of the 10-repetition maximum. Surface EMG of the vastus medialis and vastus lateralis muscles was recorded during the dynamic fatigue protocol, and EMG indices such as median frequency (MF), slope of MF (MFslope), Dimitrov muscle fatigue spectral index, and root-mean-square were evaluated for each contraction across all the 5 sets. Blood lactate concentrations were also assessed 3 times during the fatigue protocol. RESULTS: Findings revealed that EMG muscle fatigue indices such as MF, MFslope, and Dimitrov muscle fatigue spectral index were significantly altered in individuals with T2DM vs healthy individuals across the sets and repetitions for both the vastus medialis (P < .001) and vastus lateralis muscles (P < .001). There was a significantly greater rise in blood lactate in individuals with T2DM than in healthy individuals (P < .001), which was not found to be associated with changes in EMG indices of muscle fatigue. CONCLUSION: Findings suggest the existence of significantly greater fatigue in the knee extensor muscles of individuals with T2DM than healthy individuals.

Effect of eccentric exercise on markers of muscle damage in patients with chronic obstructive pulmonary disease.

Background: Eccentric exercise may be considered as an attractive alternative to conventional exercise in pulmonary rehabilitation (PR) for patients with chronic obstructive pulmonary disease (COPD). However, due to muscle damage associated with eccentric exercise, there has been reluctance in using this exercise form in PR.Objective: The aim of the present study was to investigate the effect of eccentric exercise on markers of muscle damage in patients with COPD.Methods: We analyzed 14 patients with moderate-severe COPD and 14 age-matched healthy controls. Both groups performed submaximal eccentric exercise of the elbow flexors. Muscle soreness (MS), maximum voluntary isometric contraction (MVC) of the elbow flexors, elbow range of motion (ROM), upper arm circumference (CIR), and biochemical markers such as creatine Kinase (CK) and lactate Dehydrogenase (LDH) were measured at pre-exercise, 24 h, 48 h, and 72 h following submaximal eccentric exercise.Results: There was a significant difference in markers of muscle damage, MS (p = .002), MVC (p < .001), ROM (p = .010), CIR (p < .001), and LDH (p = .001). However, no significant differences were observed in the activity of CK (p = .261) between COPD and control group following eccentric exercise which indicates greater degree of muscle damage in COPD as compared with control.Conclusion: Sub-maximal eccentric exercise causes significantly greater muscle damage in elderly COPD patients than healthy controls. Therefore, initial exercise should be progressed with lower intensities to prevent undue muscle damage in these patients.

Electromyographic Activity of Hip Musculature During Functional Exercises in Participants With and Without Chronic Ankle Instability.

OBJECTIVE: The main objective of the present study was to investigate the electromyographic (EMG) activity of gluteus medius (Gmed) and gluteus maximus (Gmax) muscles during functional exercises in subjects with chronic ankle instability (CAI) vs healthy controls. METHODS: Seventeen subjects (age, 24.4 ± 2.03 years) with CAI and 17 healthy controls (age, 24.6 ± 2.57 years) were recruited for the present study. For all participants, after testing maximum voluntary isometric contraction of the Gmed and Gmax muscle, EMG activity of these muscles was recorded during functional exercises, such as the Y Balance Test and the single-leg squat with and without Swiss ball. RESULTS: EMG activity of Gmed and Gmax was found to be significantly (P < .05) reduced during all functional exercises in subjects with CAI when compared with healthy controls. No significant differences (P > .05) were observed in the EMG activity of both muscles across different functional exercises. CONCLUSION: Our findings indicate that EMG activity of hip muscles is significantly reduced in CAI subjects, which might give an indication regarding the inclusion of hip muscle strengthening (Gmax and Gmed) in the rehabilitation of CAI. Moreover, Gmed and Gmax muscle activity did not vary during the different functional exercises within each group, which might indicate that activation pattern of these muscles are not sensitive to the type of functional task.

Taro starch: Isolation, morphology, modification and novel applications concern - A review.

Tuber and root crops are matured as fundamental food crops universally especially in tropical and subtropical regions. Among them, Taro (Colocasia esculenta) considered as 5th chief root crop due to its medicinal, ornamental and food formulation facets. Competitively it holds a considerable amount of starch even more than that to potato, sweet potato, cassava and so on. Taro corms starch (70-80%) contemplate as a cheapest abode for food industries due to its multifarious potentiality in food like stabilizer, emulsifier, fat substitute and as filler agent too. Baby foods, packaging material novelties, geriatric foods with resistant starch incorporation are the recently explored deliverables. Moreover, quality attributes of taro starch increases its behavioral versatility after modification competitively in a much better manner than native starch. This review aims to outline the current awareness about taro starch's molecular pattern, isolation procedures, properties, modifications and novel hit approaches for commercial viability. Gluten-free trait, hypoallergenic features and high digestibility are the additional benefits that widens its application scope to adapt better among pharma and textile in along with food sector.

Variations in cricket players' upper body dynamic balance across different levels of competition.

BACKGROUND: Balance ability has been associated with performance and injury prevention in athletes. Previous studies have investigated the differences in lower body dynamic balance abilities among male high school, collegiate and professional soccer players. OBJECTIVE: To investigate the differences on the Upper Quarter Y-Balance Test (UQYBT) in school, collegiate and employed cricket players. SUBJECTS: Dynamic balance data were collected for school (SCH; n = 22), collegiate (COL; n = 19) and employed (EMP; n = 15) cricket players of Jamia Millia Islamia, New Delhi, India using the UQYBT standardized protocol. METHODS: For the UQYBT, the participant reached with one hand in the medial, superolateral and inferolateral directions while maintaining three points of contact (other hand and both feet). The test was performed for both non-dominant and dominant hands. RESULTS: The SCH group had the least medial reach distance than the other two groups (p = 0.010). Also, SCH players tended to exhibit a lower composite reach score than the other groups, but this difference was not significant (p > 0.05). No bilateral differences were observed among the three groups in any of the reach directions. CONCLUSIONS: Upper body dynamic balance performance varied with the competition level. This may indicate that athletes' movement strategies may be different depending on the competition level and that normative values may need to be established for each competition level.

Adaptations of the Upper Body to Plyometric Training in Cricket Players of Different Age Groups.

CONTEXT: Neuromuscular adaptations following exercise training are believed to enhance sports performance. While abundant research is available on adaptations of the lower body to plyometric training, little is known about adaptations of the upper body to plyometric training. OBJECTIVE: To examine the effect of plyometric training on neuromuscular adaptations in cricket players of different age groups. DESIGN: Randomized parallel group active-controlled trial. SETTING: Research laboratory, school cricket ground, and sports complex field. PARTICIPANTS: Fifty-nine cricket players were randomly assigned to either the experimental group or the control group. INTERVENTIONS: The experimental group was subjected to 8 weeks of medicine ball plyometric training held thrice per week. Neuromuscular adaptations were analyzed pretraining and posttraining in 3 age groups: <18, 18-25, and >25 years. Analysis of variance was used to ascertain the training effects between and within the 6 subgroups, that is, age group <18 years (control and experimental), age group 18-25 years (control and experimental), and age group >25 years (control and experimental). MAIN OUTCOME MEASURES: Muscle activation, upper body balance, upper body power, and muscle strength. RESULTS: Out of 59, 55 participants completed the study. Subjects aged <18 years (adolescents) showed significantly greater improvements than those from the groups 18-25 years and >25 years (adults) on upper body balance and upper body power. Significant improvements were observed in the experimental subjects of all age groups on their muscle activity of biceps brachii, upper body balance, and upper body power following medicine ball plyometric training. CONCLUSIONS: Though adolescent subjects were found to be more adaptive than adult subjects, experimental subjects showed significantly greater neuromuscular adaptations to medicine ball plyometric training than controls. These findings emphasize the need for coaches and athletic trainers to inculcate medicine ball plyometric exercises in training regimes of cricket players so as to improve their upper body performance.

Postural abnormalities in phenotypes of chronic obstructive pulmonary disease.

BACKGROUND: Few studies have demonstrated postural abnormalities in patients with chronic obstructive pulmonary disease - when compared with healthy individuals. However, none of these studies have compared postural abnormalities in different phenotypes of chronic obstructive pulmonary disease. OBJECTIVE: To compare the thoracic posture between two phenotypes of chronic obstructive pulmonary disease (emphysema and chronic bronchitis) with healthy individuals. METHODS: Forty individuals with chronic obstructive pulmonary disease (20 with chronic bronchitis, 67±3.5 years, 20 with emphysema, 67.7±4 years) and 20 age-matched healthy individuals (67.3±3.9 years) underwent postural assessment which was performed using photogrammetric measurements of head protraction, shoulder protraction, thoracic kyphosis angle, coronal shoulder angle, and scapular elevation. RESULTS: Significant differences were found amongst the groups in protraction of head (emphysema vs. chronic bronchitis, mean difference=7.63°, 95% confidence interval [CI]=2.10, 13.15°; emphysema vs. healthy, 7.91°, 95% CI=2.38, 13.43°), protraction of shoulder (emphysema vs. healthy, 13.69°, 95% CI=6.96, 20.43°; chronic bronchitis vs. healthy, 8.11°, 95% CI=1.38, 14.85°), thoracic kyphosis (emphysema vs. healthy, -11.59°, 95% CI=-17.26, -5.92°; chronic bronchitis vs. healthy, -6.75°, 95% CI=-12.41, -1.08°), coronal shoulder angle (emphysema vs. chronic bronchitis, 1.01°, 95% CI=.22, 1.80°; emphysema vs. healthy, 1.59°, 95% CI=.80, 2.38°) and scapular elevation (emphysema vs. chronic bronchitis, =.74cm, 95% CI=.34, 1.15cm; emphysema vs. healthy, .99cm, 95% CI=.59, 1.40cm). CONCLUSION: People with emphysema show greater degree of postural malalignments in terms of head and shoulder protraction, thoracic kyphosis, symmetry of shoulders and scapular elevation than patients with chronic bronchitis and age-matched healthy individuals. These observations emphasize the importance of postural assessment in individuals with chronic obstructive pulmonary disease, particularly if they are emphysematous.

Effect of sensorimotor training on balance measures and proprioception among middle and older age adults with diabetic peripheral neuropathy.

PURPOSE: The aim of the study was to evaluate the effect of sensorimotor training on balance measures, and proprioception, among middle-aged and older adults with diabetic peripheral neuropathy (DPN). METHODS: A randomized controlled study with four parallel arms (two intervention groups and two control groups) was conducted at CPRS, Jamia Millia Islamia. Thirty-seven individuals were selected on the basis of inclusion and exclusion criteria. Of these, 16 middle-aged and 21 older adults were randomly allocated to intervention and control groups, respectively. Subjects in the intervention group were administered eight weeks (3days/week) of sensorimotor training, involving 10 different types of exercises, progressed from easy to hard every two weeks, along with diabetes and foot care education; subjects in control group received diabetes and foot care education only. Outcomes measures involved static and dynamic balance measures, centre of pressure (COP) range, COP sway, and proprioception, measured before and after eight weeks. RESULTS: Baseline measures showed significant age effect for timed up and go test (TUG) (p =  0.002), one leg stance (OLS) in eyes open (EO) and eyes closed (EC) (p ≤ 0.041), COP range in front (p =  0.007), back (p =  0.009) and right direction (p =  0.013), COP sway with visual feedback in front-back direction (p =  0.027), COP sway without visual feedback in left-right direction (p =  0.028), and proprioception in right direction (p =  0.026). After intervention, OLS EO and EC on both legs showed significant time effect (p ≤  0.003), group effect as well as time×group interaction (p <  0.05), and age effect and time×age interaction (p ≤  0.04). Functional reach test, TUG, COP range, COP sway, and proprioception were found with significant time effect (p <  0.03), group effect, and time×group interaction (p ≤  0.035). Age effect and time×age interaction were found to be non-significant for all COP ranges and COP sway. CONCLUSION: Sensorimotor training improved static and dynamic balance as well as proprioception measures after eight weeks of exercise intervention. Static balance showed greater improvement in the middle-aged than older aged adults, while dynamic balance and proprioception showed similar results for both.

Comparison of Complex Versus Contrast Training on Steroid Hormones and Sports Performance in Male Soccer Players.

OBJECTIVE: The purpose of this study was to compare the effects of a complex versus a contrast training regimen with steroid hormones and the performance of soccer players. METHODS: Thirty-six professional male soccer players were randomly divided into 3 equal groups: complex training (n = 12; body mass index [BMI], 22.95 ± 1.76 kg/m2), contrast training (n = 12; BMI, 22.05 ± 2.03 kg/m2), and control (n = 12; BMI, 22.27 ± 1.44 kg/m2). Players from the complex and contrast groups were trained for 6 weeks (3 d/wk). The complex group performed 4 different exercises, each composed of strength (80% of 1 repetition maximum [RM]) and power components alternately. The contrast group performed the same strengthening exercises alternately at different intensities (40% and 80% of 1 RM). All players were tested for free testosterone, cortisol, vertical jump, 20-m sprint, and agility T-test at the baseline and after 6 weeks of training. RESULTS: A 3 × 2 mixed analysis of variance revealed a significant difference in time effect (P ≤ .05), whereas a nonsignificant difference was found in the group effect for all outcome variables. group × time interaction was significant in all the variables (P < .01) except cortisol (P = .28). CONCLUSION: Complex training showed greater improvement in physical performance and free testosterone concentration compared with contrast training, whereas both types of training decreased cortisol concentration in a similar fashion.

Correlation Between Upper Body Balance, Muscle Strength, and Power in Cricketers Belonging to Different Age Groups.

OBJECTIVE: The purpose of this study was to assess correlation between variables of upper body balance, muscular strength, and power in cricketers belonging to different age groups. METHODS: Forty-eight healthy male cricketers (26 adolescents aged 14-17 years and 22 adults aged 18-25 years) were recruited from Jamia Millia Islamia, New Delhi, India. After a warm-up, the participants underwent Upper Quarter Y Balance Test, backward overhead medicine ball throw test, and back-strength testing in a random order. RESULTS: Values of the Pearson correlation coefficient for muscle strength and upper body power were found to be 0.397 and 0.499 for adolescent and adult cricketers, respectively. Correlation coefficient values for upper body balance and strength range from -0.008 to 0.05 and 0.325 to 0.414 and for upper body balance and power range from 0.059 to 0.062 and 0.133 to 0.153 for adolescent and adult cricketers, respectively. CONCLUSION: Statistically significant, moderate-sized correlations were demonstrated between muscular strength and upper body power in adolescent and adult cricketers. However, no correlations existed between upper body balance and power and upper body balance and muscular strength in these athletes.

Reliability of Electromyographic Assessment of Biceps Brachii and Triceps Brachii in Cricketers.

OBJECTIVE: The purpose of this study is to determine the intraexaminer and interexaminer reliability of electromyographic assessment of biceps brachii (BB) and triceps brachii (TB) muscles in cricketers. METHODS: Sixteen healthy male cricketers (ages 14-35 years) recruited from Jamia Millia Islamia, New Delhi, India were tested on 2 occasions that were held 1 week apart. On the first occasion, only examiner 1 performed the testing; on the second occasion, examiner 1, examiner 2, and examiner 3 all performed testing. While testing for surface electromyography (sEMG) activity of BB and TB muscles, participants were asked to produce maximal voluntary isometric contraction (MVIC), which was to be held for 5 seconds against the resistance provided by an examiner. Participants performed 3 MVICs per muscle per examiner, with a rest interval of 3 minutes between consecutive contractions. Intraclass correlation coefficient, standard error of measurement, and minimum detectable change were calculated to determine the reliability of repeated sEMG measurements. RESULTS: Nonsignificant differences were observed for the 2 trials completed by examiner 1 (paired t test) and testing done by all 3 examiners (repeated measures analysis of variance) at P < .05 for both BB and TB. Intraclass correlation coefficient values ranged from .84 to .86 for BB and .89 to .98 for TB. Standard error of measurement (minimum detectable change) was .052 (.144) mV and .041 (.114) mV for BB intraexaminer and interexaminer reliability testing, respectively, and .018 (.051) mV and .043 (.119) mV for TB intraexaminer and interexaminer reliability testing. Ninety-five percent of the mean differences between almost all of the repeated measurements were found to lie within the agreement intervals estimated by Bland-Altman plots. CONCLUSION: This preliminary study suggests that sEMG is a reliable tool with excellent intraexaminer and interexaminer reliability for assessing the activity of BB and TB muscles in male cricketers. These findings suggest that sEMG can be used to assess MVIC activity of these muscles in clinical settings, as well as in research area.

Association between handgrip strength and back strength in adolescent and adult cricket players.

Background Although a significant amount of research has been conducted on handgrip strength and its association with anthropometric variables, very few researchers have focused on assessment of back strength and its relationship with anthropometric variables in cricketers. Objective To investigate the degree of correlation between handgrip strength and back strength in cricket players of different maturity levels and to find the correlations of handgrip strength and back strength with anthropometric variables of age, height, body weight and body mass index (BMI). Methods Twenty-four adolescents; aged 16.6 ± 0.8 years and 32 adult cricketers aged 24 ± 4.6 years were tested for height, body weight, BMI, hand grip strength and back strength. t values, Cohen's d and Pearson's correlation coefficients were calculated. Results Hand grip strength and back strength were not found to correlate with each other at p ≤ 0.05 in adolescent players while a statistically significant large sized correlation was observed in adult cricketers at p = 0.001. Back strength and body weight were found to have a statistically significant moderate sized correlation with each other (r = 0.453 in the adolescent group and r = 0.355 in the adult group). Significant positive correlations were observed for left hand grip strength with height, body weight and BMI and also between back strength and age in the adult population of cricketers. Conclusion A significantly large correlation exists between handgrip strength and back strength in adult cricketers with no such correlation found for adolescent cricketers. Data of the present study justify its utility in the case of selection, assessment and rehabilitation of cricket players.

Co-Existence of hypertension worsens post-exercise cardiac autonomic recovery in type 2 diabetes.

BACKGROUND: Cardiac autonomic neuropathy (CAN) is a commonly overlooked complication of Type 2 Diabetes Mellitus (T2DM) characterized by imbalance between sympathetic and parasympathetic supply to the heart. The susceptibility of heart to dysrhythmias and fatal events increases during and after exercise due to a shift in autonomic regulation. Diabetes and hypertension (HTN) frequently occur concurrently and both conditions lead to impaired cardiac autonomic control. However, their impact together on post-exercise autonomic recovery remains to be explored. OBJECTIVE: The objective of the study was to investigate the effect of co-existence of HTN on cardiac autonomic recovery (assessed by heart rate recovery and heart rate variability) in patients with T2DM. METHODS: Forty eight type 2 diabetic patients (24 normotensive, 24 hypertensive), 24 non-diabetic patients with essential HTN, and 27 healthy controls, were recruited into the study and assessed for heart rate recovery (HRR) following a graded maximal test. Also, heart rate variability (HRV) was recorded before and following the bout of maximal exercise. RESULTS: Heart rate recovery at 1 (HRR1min) and 2 (HRR2min) minute(s) showed significant effects for DM (p < 0.001) and HTN (p < 0.001), while DM × HTN interaction was found to be non-significant. Resting HRV showed a significant decline in time-domain variables for the DM group (p < 0.01). Recovery of HRV showed a significant effect of time (p < 0.05) for all indices, the group effect was found significant only for time-domain measures (p < 0.05). CONCLUSION: Both HRR and HRV recovery were impaired in DM and HTN. Moreover, the co-existence of HTN had a synergistic effect, causing further worsening of autonomic recovery in T2DM.

Effect of glycemic control and disease duration on cardiac autonomic function and oxidative stress in type 2 diabetes mellitus.

PURPOSE: Cardiac autonomic neuropathy (CAN) is a commonly overlooked complication of type 2 diabetes mellitus (T2DM), with a complex pathogenesis involving hyperglycemia-induced oxidative stress which results in neuronal ischemia and cellular death. The level of hyperglycemia as well as disease duration might be significant determinants of the prognosis of T2DM, but limited studies have explored their relationship with these diabetic complications. Therefore, the purpose of this study was to examine the effect of glycemic control and disease duration on cardiac autonomic function and oxidative stress in patients with T2DM. METHODS: 60 T2DM patients along with 63 healthy controls were recruited for the study. Diabetic patients were further classified based on glycemic control (HbA1c levels <8% vs. ≥8%) and disease duration (<5 vs. 5-10 vs. >10 years). All participants were assessed for cardiac autonomic function (HRR: heart rate recovery; HRV: heart rate variability), levels of antioxidant enzymes (CAT: catalase; SOD: superoxide dismutase), serum nitric oxide (NO) and other cardiometabolic risk factors (resting blood pressure, glycemic and lipid profile). RESULTS: T2DM patients showed a significant reduction in HRR, HRV, CAT, SOD and an increase in LFnu, LF: HF ratio and NO. These impairments were significantly greater for the group with poor glycemic control (p < 0.05). However, no difference for these parameters was observed with respect to different disease durations. CONCLUSION: Cardiac autonomic regulation and endogenous antioxidant defense were compromised and levels of nitric oxide found to be raised in patients with Type 2 diabetes. These findings were more pronounced in subjects with poor glycemic control.

Effect of upper body plyometric training on physical performance in healthy individuals: A systematic review.

OBJECTIVE: To determine the impact of upper body plyometric training (UBPT) on physical performance parameters such as strength, ball throwing speed, ball throw distance and power in healthy individuals. METHODS: PubMed, Scopus, ResearchGate and ERIC databases were searched up to August 2017. Selection of articles was done if they described the outcomes of an upper body plyometric exercise intervention; included measures of strength, ball throwing speed, ball throw distance, or power; included healthy individuals; used a randomized control trial; and had full text available in English language. The exclusion criteria were unpublished research work and clubbing of UBPT with some other type(s) of training apart from routine sports training. PEDro scale was used to rate the quality of studies eligible for this review. RESULTS: Initially 264 records were identified and out of them only 11 articles met the eligibility criteria and were selected (PEDro score = 4 to 6). Though large to very small effects observed in improving ball throwing velocity, ball throwing distance, power and strength of upper limb muscles after UBPT, the results should be implemented with caution. CONCLUSION: Inconclusive results obtained preclude any strong conclusion regarding the efficacy of UBPT on physical performance in healthy individuals.