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1.
Int Orthop ; 48(5): 1225-1231, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38407597

RESUMEN

PURPOSE: We conducted a retrospective analysis of prospectively collected data to evaluate (1) the extent of surgical correction following minimally invasive periacetabular osteotomy, (2) improvements in functional outcomes and any potential predictors for favourable outcome, and (3) complications after minimally invasive periacetabular osteotomy. METHODS: A total of 352 minimally invasive periacetabular osteotomy procedures were performed on 312 hip dysplasia patients between 2013 and 2020. Radiological parameters such as lateral centre edge angle, acetabular index, and Tönnis grade of arthritis were calculated. Patients also completed a range of patient reported outcome measures. Wilcoxon signed-rank tests were performed to assess for differences between patient reported outcome measures and radiological outcomes across the follow-up periods. Univariate linear regression and logistic regression were used to assess for predictors of change in functional outcome. RESULTS: Patients had a significant correction in mean lateral centre edge angle from 17.2° to 35.3° (p < 0.001) and mean acetabular index from 13.2° to - 0.82°. At one year follow-up all patient reported outcome measures were significantly greater than their baseline measurements and this improvement was maintained at two years. Changes in patient reported outcome measures were independent of radiological parameters such as change in the lateral centre edge angle and acetabular index, pre-operative Tönnis grade, and patient factors such as age and sex. A total of 5.11% of patients developed post-operative complications, with four requiring posterior column fixation. Four patients (1.12%) needed a total hip replacement. CONCLUSION: Minimally invasive periacetabular osteotomy is a safe procedure that provides significant functional outcome improvements following surgery at six months which is maintained at two years. More than three-fourths of patients achieved improvement of iHOT-12 score beyond the minimal clinically important difference and more than half of the patients achieved substantial clinical benefit for iHOT-12 score.


Asunto(s)
Luxación Congénita de la Cadera , Luxación de la Cadera , Cirujanos , Humanos , Luxación de la Cadera/cirugía , Estudios de Seguimiento , Estudios Retrospectivos , Resultado del Tratamiento , Luxación Congénita de la Cadera/cirugía , Acetábulo/diagnóstico por imagen , Acetábulo/cirugía , Osteotomía/efectos adversos , Osteotomía/métodos
2.
Br J Hosp Med (Lond) ; 83(1): 1-3, 2022 Jan 02.
Artículo en Inglés | MEDLINE | ID: mdl-35129381

RESUMEN

This editorial discusses the 'Enhancing Junior Doctors' Working Lives' report from Health Education England and emphasises the importance of junior doctors reading it and engaging with the content.


Asunto(s)
Actitud del Personal de Salud , Cuerpo Médico de Hospitales , Inglaterra , Humanos
4.
Nucl Med Commun ; 33(7): 701-7, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22495080

RESUMEN

AIM: To investigate whether in lower extremity lymphoedema, lymph proteins enter blood before they do the thoracic duct. METHODS: Retrospective analysis of routine lymphoscintigraphy in 69 adults imaged at 5, 45 and 150 min following bilateral subcutaneous web space injection of Tc-nanocolloid was carried out. Regions of interest were placed over the liver and ilioinguinal lymph nodes bilaterally on the anterior images at 45 and 150 min. Individual minor (0.5 point for each) and major (1 point for each) criteria of abnormal scintigraphy were applied to each limb and summed to give a lymphoscintigraphic abnormality score. An abnormal limb had a score ≥1. RESULTS: The ratio of hepatic counts per pixel to total bilateral ilioinguinal counts (L/N ratio) was higher in patients with abnormal results on lymphoscintigraphy (median 6.2; interquartile range 4.0-15.6 pixels×10; n=48) compared with that in patients with normal lymphoscintigraphic results (2.5 [1.5-5.0] pixels×10; n=21; P<0.0002). In the abnormal group, the lymphoscintigraphic score (two limbs summed) correlated with the 150-min L/N ratio (r s=0.42; P<0.005). L/N ratios at 45 and 150 min correlated in the abnormal group (r s=0.44; P<0.005) but not in the normal group (r s=0.3; P>0.05). The 45-min activity, as a percentage of the 150-min activity, was higher in lymph nodes than in the liver in both the abnormal (35.0 [8.2-50.0] vs. 10.6 [5.8-30.0]%; P<0.0001]) and normal groups (38.3 [18.4-63.5] vs. 23.3 [12.4-33.1]%; P<0.05), and, with respect to the liver, was higher in the normal group (P<0.01). CONCLUSION: In lymphoedema, more lymph proteins enter blood proximal to the thoracic duct. The time courses of nodal and hepatic activities suggest that access may occur within nodes themselves.


Asunto(s)
Proteínas Sanguíneas/análisis , Hígado/diagnóstico por imagen , Linfedema/diagnóstico por imagen , Adolescente , Adulto , Anciano , Estudios de Casos y Controles , Humanos , Linfocintigrafia/métodos , Persona de Mediana Edad , Compuestos de Organotecnecio , Estudios Retrospectivos , Adulto Joven
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