Asunto(s)
Artritis Gotosa , Gota , Artritis Gotosa/complicaciones , Extremidades , Gota/complicaciones , HumanosAsunto(s)
Alopecia Areata/virología , COVID-19/virología , SARS-CoV-2/patogenicidad , Alopecia Areata/diagnóstico , Alopecia Areata/inmunología , Antivirales/uso terapéutico , COVID-19/diagnóstico , COVID-19/inmunología , Femenino , Interacciones Huésped-Patógeno , Humanos , Hidroxicloroquina/uso terapéutico , Persona de Mediana Edad , Factores de Riesgo , SARS-CoV-2/efectos de los fármacos , SARS-CoV-2/inmunología , Resultado del Tratamiento , Tratamiento Farmacológico de COVID-19RESUMEN
Interstitial granulomatous dermatitis with arthritis (IGDA), also known as Ackerman's syndrome, is a rare cutaneous disease classically characterized by the triad of cutaneous cords, a typical histologic infiltrate mainly constituted by histiocytes and arthritis/connective tissue disease. Here we report the case of IGDA with the typical clinical and histological features in a patient affected by lupus erythematosus. In this article we underline that IGDA may have a variety of different clinical and histological features. The rope sign is typical but infrequent, while histology is usually characteristic and shows a dermal inflammatory infiltrate, with a predominance of histiocytes, localized interstitially and in a palisaded array between collagen fibres, that show signs of degeneration. Clinical and histological differential diagnoses are discussed.
