RESUMEN
As a newly developed technique to slice GaN substrates, which are currently very expensive, with less loss, we previously reported a laser slicing technique in this journal. In the previous report, from the perspective of GaN substrate processing, we could only show that the GaN substrate could be sliced by a laser and that the sliced GaN substrate could be reused. In this study, we newly investigated the applicability of this method as a device fabrication process. We demonstrated the thinning of GaN-on-GaN high-electron-mobility transistors (HEMTs) using a laser slicing technique. Even when the HEMTs were thinned by laser slicing to a thickness of 50 mm after completing the fabrication process, no significant fracture was observed in these devices, and no adverse effects of laser-induced damage were observed on electrical characteristics. This means that the laser slicing process can be applied even after device fabrication. It can also be used as a completely new semiconductor process for fabricating thin devices with thicknesses on the order of 10 mm, while significantly reducing the consumption of GaN substrates.
RESUMEN
We have investigated the possibility of applying lasers to slice GaN substrates. Using a sub-nanosecond laser with a wavelength of 532 nm, we succeeded in slicing GaN substrates. In the laser slicing method used in this study, there was almost no kerf loss, and the thickness of the layer damaged by laser slicing was about 40 µm. We demonstrated that a standard high quality homoepitaxial layer can be grown on the sliced surface after removing the damaged layer by polishing.
RESUMEN
AIM: The viscoelastic properties of the artery are known to be altered in patients with vascular diseases. However, few studies have evaluated the viscoelasticity of the vascular wall in humans. We sought to investigate the degree of viscoelastic deterioration of the carotid artery and assess its clinical implications. METHODS: Between January 2011 and June 2013, patients in whom the toe-brachial index was measured at the vascular laboratory were included in this single-institute retrospective observational study. I(ï¼), a parameter of viscoelastic deterioration, was computed using a non-invasive ultrasonic Doppler effect sensor on the carotid artery. I(ï¼) is a non-dimensional value, and I(ï¼)>0 is considered abnormal. Other patient characteristics were identified and tested for correlations with I(ï¼). RESULTS: The study included 383 patients. The mean I(ï¼) value was 0.13 ± 0.22 with a normal distribution. Factors that increased the I(ï¼) value were a female sex (0.18 ± 0.23 vs. 0.10 ± 0.21, P<0.001), age ≥ 60 (0.14 ± 0.22 vs. 0.06 ± 0.23, P<0.05) and systolic blood pressure of >140 (0.15 ± 0.22 vs. 0.10 ± 0.22, P<0.05). I(ï¼) abnormality was a significant risk factor for coronary artery disease (OR 2.20, 95% CI 1.00-4.80, P<0.05) in a univariate analysis. In the multivariate analysis, I(ï¼) abnormality was also found to be an independent risk factor for coronary artery disease (OR 4.56, 95% CI 1.21-30.1, P<0.05). CONCLUSIONS: I(ï¼) may reflect the degree of atherosclerotic changes in the arterial wall and could possibly be used to predict coronary artery disease.
Asunto(s)
Trastornos de la Coagulación Sanguínea/complicaciones , Arterias Carótidas/patología , Enfermedad de la Arteria Coronaria/diagnóstico , Enfermedad de la Arteria Coronaria/etiología , Módulo de Elasticidad , Estrés Mecánico , Enfermedades Vasculares/complicaciones , Anciano , Trastornos de la Coagulación Sanguínea/fisiopatología , Viscosidad Sanguínea , Enfermedad de la Arteria Coronaria/sangre , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , Estudios Retrospectivos , Enfermedades Vasculares/fisiopatología , ViscosidadRESUMEN
This research was conducted to investigate frequency response of blood vessel wall. The principal frequency of blood vessel wall, f1 was found to decrease with progression of atherosclerosis and irregularity of the vibration trajectory of blood vessel wall was found to increase. When an aneurysm appeared, a new vibration wave was found to appear in the high frequency region, f2. When the aneurysm wall has enough strength, intensity of high frequency wave was found to increase. However, it decreases with decrease in the strength of aneurysm wall. The visco-elastic deterioration of blood vessel wall was found to well correlate with the changing characteristics of f1. A two-dimensional representation of f1 and f2 was conducted which tracks the progression of atherosclerosis and aneurysm. It will enable us to diagnose the introduction period of operation of blood vessel wall of atherosclerosis with an aneurysm.