RESUMEN
Unlike the traditional studies on multiagent systems (MASs), this article investigates a class of MASs with spatial properties, whose agents are modeled by partial differential equations (PDE), in addition, to make the model more comprehensive, the Markovian switching topology with partially unknown probability is taken into account. The purpose of this article is to achieve the bipartite consensus for the above PDE-based MASs. In fact, the consideration of spatial factors in MASs will exacerbate the network transmission pressure, to overcome this problem, a novel spatiotemporal event-triggered mechanism is developed. Compared with the existing event-triggered mechanism, the proposed one is not only time-dependent but also covers the influence of spatial variables on the trigger conditions, which helps to further reduce the triggering frequency. Finally, three examples are given to verify the validity of the conclusion we proposed.
RESUMEN
Bacterial proteins targeting the appropriate subcellular sites are the base for their proper function. Several studies have shown that the anionic phospholipid cardiolipin (CL), a conical lipid preferring negative membrane curvature, modulates the lipid bilayers' structure, which impacts the activity of their resident proteins. Due to the favor of negative membrane curvature, CL is not randomly distributed in the bacterial plasma membrane. In contrast, it gathers in particular parts of the cell membrane to form microdomains, in which many functional membrane proteins are accumulated and carry out diverse physiological processes of bacteria, such as cell division, metabolism, infection, and antibiotic residence. In addition, CL has a unique structure that carries two negative charges, which makes it play a pivotal role in protein assembly, interaction, and location. These characteristics of CL make it closely related to many crucial physiological functions of bacteria. Here, we have reviewed the mechanism of protein dynamics mediated by CL initiated on the bacterial membrane. Furthermore, we studied the effect of CL on bacterial infection and antibiotic residence. Finally, the CL-targeting therapeutic agents for antibacterial therapy are also examined.