Summated Xerostomia Inventory to detect both xerostomia and salivary gland hypofunction.

OBJECTIVE: This study aims to evaluate the diagnostic performance of the Summated Xerostomia Inventory (SXI-ID) questionnaire in detecting xerostomia and salivary gland hypofunction (SGH). SUBJECTS AND METHODS: This diagnostic study first underwent a validity and reliability test. Participants were randomly sampled from the Geriatric Clinics of Dr. Hasan Sadikin Hospital, Bandung, Indonesia. The SXI-ID was generated through a forward-backward translation, after which its validity (item-total item correlations), internal consistency (Cronbach's alpha), and test-retest reliability (kappa statistic) were all assessed. The diagnostic performance of the SXI-ID in detecting SGH was evaluated using receiver operating characteristic (ROC) curve analysis. RESULTS: A total of 60 participants (aged ≥60 years) were involved in this study, most of whom were female (75%). The internal consistency of the SXI-ID was acceptable (α = 0.823), and its test-retest reliability was perfect (K= 1.00). ROC analysis showed that an SXI-ID cut-off value > 11 could detect SGH with a sensitivity of 96.0%, a specificity of 100.0%, and an area under the curve of 0.985 (p < 0.001). CONCLUSIONS: The SXI-ID questionnaire is a valid and reliable tool to detect xerostomia and SGH in older Indonesians, and a score of 11 or above is useful to identify those with a low salivary flow.

The association of admission random blood glucose concentration and body-mass index with mortality in COVID-19 patients.

OBJECTIVE: This study aimed to investigate the association between hyperglycemia and body mass index (BMI), along with other associated comorbidities in hospitalized COVID-19 patients among the Indonesian population. PATIENTS AND METHODS: This was a retrospective study conducted at Hasan Sadikin Hospital, Bandung between March 1, 2020, and August 30, 2020. Data were analyzed using the chi-square test for categorical data and unpaired t-test and Mann-Whitney alternative test for numerical data using SPSS version 24.0 (IBM SPSS Statistics for Windows, Version 24.0. IBM, Armonk, NY, USA) and GraphPad Prism version 7.0 for Windows. RESULTS: A total of 142 hospitalized COVID-19 patients were documented between March and August 2020 at the Hasan Sadikin Hospital. Among the 142 patients, 116 (81.7%) survived, while 26 (18.3%) died. Sex, age, BMI, number of comorbidities, heart rate, respiratory rate, peripheral oxygen saturation, platelet count, random blood glucose (RBG), and length of stay (LOS) were significantly associated with mortality. Multivariate analyses demonstrated that admission RBG levels > 140 mg/dl were independently associated with an increased risk of mortality in COVID-19 patients (OR 4.3, 95% CI 1.1-17.5, p = 0.043), while BMI > 25 kg/m2 was significantly associated with reduced mortality (OR, 0.22; 95% CI 0.05-0.88, p = 0.033). CONCLUSIONS: Admission hyperglycemia, indicated by an increase in RBG levels >140 mg/dL, is independently associated with an increased risk of mortality in hospitalized COVID-19 patients, while obesity (BMI >25 kg/m2) might have protective properties against the risk of death.