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Intern Med ; 63(6): 791-798, 2024 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-37532549

RESUMEN

A 61-year-old woman was administered 35 cycles of pembrolizumab for the treatment of recurrent endometrial cancer, achieving a complete response. She presented with asymptomatic pancreatic enlargement and elevated hepatobiliary enzymes, but amylase and lipase levels were within the normal ranges. Intrapancreatic bile duct stenosis due to pancreatic enlargement was present, mimicking autoimmune pancreatitis on computed tomography performed before the onset of clinical manifestations. A histological examination of a biopsy specimen showed lymphocyte and plasma cell infiltration with dense fibrosis in the stroma. The patient was successfully treated with oral prednisolone. There were no manifestations of recurrent pancreatitis after tapering the prednisolone dose.


Asunto(s)
Enfermedades Autoinmunes , Pancreatitis Autoinmune , Pancreatitis , Femenino , Humanos , Persona de Mediana Edad , Enfermedades Autoinmunes/inducido químicamente , Enfermedades Autoinmunes/diagnóstico , Enfermedades Autoinmunes/tratamiento farmacológico , Hipertrofia , Inhibidores de Puntos de Control Inmunológico , Recurrencia Local de Neoplasia , Pancreatitis/diagnóstico , Pancreatitis/diagnóstico por imagen , Prednisolona/uso terapéutico
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