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BACKGRUOUND: The combined use of biomaterials for regeneration may have great biological relevance. This study aimed to compare the regenerative potential of biphasic calcium phosphate (BCP) alone and with growth factor enamel matrix derivatives (EMDs) for the regeneration of intrabony defects at 1 year. METHODS: This randomized controlled trial included 40 sites in 29 patients with stage II/III periodontitis and 2/3 wall intrabony defects that were treated with BCP alone (control group) or a combination of BCP and EMD (test group). BCP alloplastic bone grafts provide better bio-absorbability and accelerate bone formation. EMDs are commercially available amelogenins. Mean values and standard deviations were calculated for the following parameters: plaque index (PI), papillary bleeding index (PBI), vertical probing pocket depth (V-PPD), vertical clinical attachment level (V-CAL), and radiographic defect depth (RDD). Student paired and unpaired t-tests were used to compare the data from baseline to 12 months for each group and between the groups, respectively. The results were considered statistically significant at p<0.05. RESULTS: At 12 months, the PI and PBI scores of the control and test groups were not significantly different (p>0.05). The mean V-PPD difference, V-CAL gain, and RDD difference were statistically significant in both groups at 12 months (p<0.001 for all parameters). Intergroup comparisons showed that the mean V-PPD reduction (2.13±1.35 mm), V-CAL gain (2.53±1.2 mm), and RDD fill (1.33±1.0 mm) were statistically significant between the groups at 12 months (p<0.001 for all parameters). CONCLUSION: BCP and EMDs combination is a promising modality for the regeneration of intrabony defects.
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BACKGRUOUND: Chronic infectious, inflammatory, or neoplastic disorders are associated with anemia of chronic disease. Chronic inflammatory diseases such as periodontitis may contribute to masked anemia, especially in smokers. This study was aimed at verifying and comparing the efficacy of nonsurgical periodontal therapy (NSPT) for improving anemia among chronic periodontitis patients with and without the habit of smoking. METHODS: Thirty systemically healthy individuals with chronic periodontitis were divided into two groups of 15 each, smokers (group A) and nonsmokers (group B). The groups were compared based on hematological parameters such as serum erythropoietin (SE) and serum ferritin (SF) levels at baseline and 3 months after NSPT for anemia evaluation. RESULTS: The baseline SE levels in groups A and B were 11.84 and 15.19 mIU/mL (p=0.031), respectively; the corresponding levels at 3 months after NSPT were 13.00 and 17.74 mIU/mL (p=0.022). The baseline SF levels in groups A and B were 95.49 and 44.86 ng/mL (p=0.018), respectively; the corresponding levels at 3 months after NSPT were 77.06 and 39.05 ng/mL (p=0.009). Group B showed a significant increase and decrease in the SE and SF levels, respectively, at 3 months after NSPT (p=0.035 and p=0.039, respectively), whereas group A showed insignificant changes (p=0.253 and p=0.618, respectively). CONCLUSION: NSPT led to an improvement in anemia among chronic periodontitis patients. However, the improvement is less in smokers compared to that in nonsmokers. Furthermore, SF and SE levels might serve as effective biomarkers for assessing anemia in smokers and nonsmokers with chronic periodontitis.
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BACKGROUND: Periodontal disease is an inflammatory process resulting in clinical attachment loss (CAL), pocket depth (PD), and resulting in the loss of alveolar bone. Diagnostic imaging provides an adjunctive guidelines to assess the alveolar bone height in addition to clinical parameters such as PD and CAL. AIMS AND OBJECTIVES: The objectives of the study are to determine whether the digital intraoral periapical (IOPA) radiographs can be reliably used as an alternative to cone-beam computed tomography (CBCT) in the diagnosis of intrabony defects. MATERIALS AND METHODS: A total of 25 patients with the presence of intrabony defects were included in the study. All the radiographic parameters were recorded using digital IOPA and CBCT. Various intrabony defect morphological characteristics such as height, depth, width, and angle were measured and compared between digital IOPA and CBCT. STATISTICS: The data was subjected to statistical analysis. Mann-Whitney U-test was performed for interexaminer comparison and independent t-test for intergroup comparison. RESULTS: The mean intergroup comparison values between digital IOPA and CBCT in relation to defect width were 3.22 ± 1.10 and 3.20 ± 1.16, respectively (P = 0.970), in relation to defect depth were 7.71 ± 2.3 and 7.91 ± 2.4, respectively (P = 0.769), in relation to defect height were 3.80 ± 1.20 and 3.90 ± 1.2, respectively (P = 0.794), and in relation to defect angle were 34.82 ± 8.4 and 35.28 ± 0.8.6, respectively (P = 0.851). CONCLUSION: With the drawbacks of such as high radiation exposure, unavailability, and high financial cost, digital IOPA with digital software can be used as an alternative to CBCT for measuring intrabony defect morphological characteristics in periodontitis patients.
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AIMS AND OBJECTIVES: People in rural areas neglect oral health as they lack awareness on dental diseases and also due to inadequate availability of dental services. The prevalence of illiteracy is also a reason which can be attributed to a poor oral health. This epidemiological study is undertaken to assess the prevalence of periodontal diseases in the rural population of Mustabad - in Krishna, Andhra Pradesh. MATERIALS AND METHODS: A cross-sectional study based on randomized sampling method was carried out using the WHO assessment form (1997) on a population of 470. The data were subjected to statistical analysis using Statistical Package for Social Sciences Version 15.0. RESULTS: The subjects were 220 males and 250 females. Maximum numbers of subjects were in the age group of 35-44 years (21.91%). Prevalence of periodontal disease was found to be 73.62%. The periodontal status deteriorated with aging. Prevalence of periodontitis was higher in females (56.35%) compared to males (43.65%). Males had a higher prevalence of deep pockets (3.18%), whereas females had a higher prevalence of shallow pockets (3.20%). Females had twice the bleeding tendency (18.80%) compared to males (8.64%). CONCLUSION: The increasing prevalence of periodontal diseases is an impending problem which needs immediate intervention, if not it would have a serious negative impact on the future oral health. The need of the hour is more epidemiological studies with a bigger sample are required.