The evidence of effectiveness of isometric resistance training on the management of hypertension in adults: an umbrella review.

Hypertension is the leading risk factor for cardiovascular disease yet also one of the most readily preventable causes of death. Isometric resistance training (IRT) has gained increasing popularity in recent times as a viable nonpharmacological management option for hypertension. Whilst there have been several reviews on this topic, with varying findings, this umbrella review aimed to summarize the current evidence underpinning the effectiveness of IRT for hypertension. Quantitative systematic reviews and meta-analyses published in English were considered for inclusion. Commercially produced and grey literature was searched between December 2021 and January 2022. Methodological quality of included reviews was determined using the AMSTAR 2 critical appraisal tool. Customized data extraction tools were developed for this review and data were synthesized using the National Health and Medical Research Council FORM Framework. Twelve reviews published between 2011 and 2021 of varying methodological quality were identified. Isometric handgrip exercise training with four sets of 2-min contractions and 1 min rest period between each set was the most utilized intervention, undertaken three times per week for at least 8 weeks. Collectively, there is consistent evidence to indicate IRT has positive impacts on SBP and DBP as well as mean arterial pressure. These positive impacts were reported for normotensive as well as hypertensive individuals. Given IRT is a readily available, easy-to-use intervention with minimal financial cost, it could be considered a viable treatment option for people with, and at risk of, hypertension.

Supporting strategies for enhancing vegetable liking in the early years of life: an umbrella review of systematic reviews.

BACKGROUND: Many children worldwide do not eat recommended amounts of vegetables. Disliking vegetables is a key factor associated with low intake. OBJECTIVE: This umbrella review synthesized systematic reviews to determine the effectiveness of sensory and behavioral strategies to facilitate liking of vegetables (primary outcome) in young children up to 5 y of age, as key predictors of vegetable intake (secondary outcome). METHODS: Nine databases were searched up to May 2019 (updated in September 2020). Two reviewers independently conducted study screening and selection, data extraction, and assessment of methodological quality using AMSTAR 2 (A MeaSurement Tool to Assess systematic Reviews). Eleven reviews (n = 1 rated strong quality, n = 4 moderate quality, n = 6 low/critically low quality) examining 85 primary studies met the review criteria: systematic reviews and meta-analyses of primary studies (any quantitative design) that examined sensory or behavioral strategies on vegetable liking or intake (outcomes reported separately for children ≤5 y). Strategy effectiveness was synthesized into 3 categories based on evidence strength: 1) promising (large and consistent body of moderate quality evidence), 2) emerging (small to moderate body of mixed consistency and quality evidence), and 3) limited (small body of limited consistency and quality evidence). RESULTS: Promising evidence was identified for repeated exposure to a single or a variety of vegetables. Emerging evidence was identified for several strategies that increase familiarity with vegetable flavors (e.g., via exposure in utero and through breast milk, and a "vegetable first" approach to complementary feeding) and/or willingness to try vegetables (e.g., via parental role modeling, nonfood rewards, and vegetable-based story books). CONCLUSIONS: Current evidence supports incorporation of tailored advice into guideline documents for parents and carers to repeatedly expose their children to a variety of vegetables to increase vegetable intake. Ongoing robust research on strategies to facilitate children's liking of vegetables is warranted to strengthen the evidence base underpinning advice for parents and health professionals.

Obesity, the new childhood disability? An umbrella review on the association between adiposity and physical function.

The adverse physical impacts of childhood obesity are increasingly being recognized. The objective of this study is to examine relationships between physical function and adiposity in youth. An umbrella review searched seven databases from inception to May 2019 for systematic reviews examining associations between adiposity and physical function in 0-20-year-olds. Findings were synthesized using the International Classification of Functioning, Disability and Health Framework and NHMRC FORM. Seventeen of 21 systematic reviews reported impairments to body function, including cardiorespiratory fitness (CRF), muscle function, balance/coordination, gait biomechanics, pain and injury. Six reviews reported activity restrictions in motor skills, running speed/agility and functional mobility, and two found inverse associations between adiposity and physical health-related quality of life (p-HRQOL). Some causal relationships indicated that adiposity inversely predicted p-HRQOL/CRF and CRF/muscle function inversely predicted adiposity. Assessments of physical function were heterogeneous and impacts on participation in life situations meaningful to the individual were largely unknown. Substantial evidence associates childhood overweight/obesity with reduced physical function. Associations were mainly cross-sectional, with causative evidence for some outcomes. Comprehensive physical function assessments by qualified health professionals are needed, along with targeted interventions to address deficits. Research should further examine causality of relationships, underlying mechanisms and participation challenges in real-life contexts.