Alimentacion y actividad fisica durante el confinamiento por Covid-19 en estudiantes de la Universidad Nacional del Litoral, Santa Fe, Argentina / Diet and physical activity during covid-19 lockdown in students at Universidad Nacional del Litoral, in Santa Fe, Argentina

Introducción: La influencia que la vida académica ejerce sobre los estilos de vida en estudiantes universitarios es un hecho reconocido. Como estrategia adoptada para evitar la propagación masiva del virus SARS-CoV-2, el gobierno argentino decretó en 2020 medidas de aislamiento y distanciamiento social que derivaron en el cese de la presencialidad de los estudiantes en las universidades; por ello, esta situación particular representó un escenario desconocido. Objetivos: Evaluar cambios en los hábitos alimentarios y de actividad física (AF), en el contexto del confinamiento por COVID19, en estudiantes de la Universidad Nacional del Litoral. Materiales y Métodos: Se realizó un estudio transversal, observacional y descriptivo, durante junio a agosto de 2020. Se utilizó un cuestionario online para indagar datos demográficos, alimentación y AF, desarrollado ad hoc y validado por expertos (confiabilidad: alfa de Cronbach=0,85) y prueba piloto. La muestra poblacional (no probabilística) incluyó 1259 estudiantes, de 22 ± 3 años, con predominio femenino (78%). Resultados: El 63% vivía en el mismo lugar que durante la presencialidad y el 96% acompañado. Un 63% percibió que las medidas de confinamiento modificaron su relación con la alimentación, mayormente por cuestiones emocionales (71%). El 81% aumentó el consumo de comidas caseras y el 26% utilizó delivery con mayor frecuencia. Un 49% calificó su alimentación como medianamente saludable; la mayoría (71%) realizó las cuatro comidas principales y, entre quienes omitieron al menos una (29%), los principales motivos fueron no tener hambre (38%) y levantarse tarde (34%). Entre quienes bebían alcohol, el 56% consumió menos. El 62% disminuyó la actividad física y el 20% la mantuvo. Conclusiones: El confinamiento social impactó negativamente disminuyendo la actividad física, mientras que la alimentación resultó modificada tanto por aspectos negativos como por otros positivos. Esta información resulta valiosa para plasmar intervenciones destinadas a mantener estilos de vida saludables en esta población universitaria

Introduction: The influence that academic life exerts on lifestyle of university students is a recognized fact. As a strategy adopted to prevent the massive spread of the SARS-CoV-2 virus, the Argentinian government decreed isolation and social distancing measures in 2020 that led to the cessation of attendance by students at universities; therefore, this particular situation represented an unknown scenario. Objectives: To evaluate changes in habits eating and physical activity (PA), in the context of confinement by COVID-19, in students of the Universidad Nacional del Litoral. Materials and Methods: A cross-sectional, observational and descriptive study was carried out from June to August 2020. An online questionnaire was used to investigate demographic data, diet and PA, developed ad hoc and validated by experts (reliability: Cronbach's alpha=0.85) and pilot test. The population sample (non-probabilistic method) included 1259 students, 22 ±3 years old, predominantly female (78%). Results: 63% lived in the same place as during the attendance and 96% were accompanied. Moreover, 63% perceived that confinement measures modified their relationship with food, mostly for emotional reasons (71%). On the other hand, 81% increased their consumption of homemade meals and 26% used delivery more frequently. 49% of the students described their diet as moderately healthy; the majority (71%) ate all four main meals, and among those who skipped at least one (29%), the main reasons were not being hungry (38%) and getting up late (34%). Among those who drank alcohol, 56% consumed less.In other matters, 62% decreased physical activity and 20% maintained it. Conclusions: Social confinement had a negative impact by decreasing physical activity, while diet was modified by both negative and positive aspects. This information is valuable to capture interventions aimed at maintaining healthy lifestyles in this university population

Development of Computational Approaches with a Fragment-Based Drug Design Strategy: In Silico Hsp90 Inhibitors Discovery.

A semi-exhaustive approach and a heuristic search algorithm use a fragment-based drug design (FBDD) strategy for designing new inhibitors in an in silico process. A deconstruction reconstruction process uses a set of known Hsp90 ligands for generating new ones. The deconstruction process consists of cutting off a known ligand in fragments. The reconstruction process consists of coupling fragments to develop a new set of ligands. For evaluating the approaches, we compare the binding energy of the new ligands with the known ligands.

Valoración de los patrones de consumo alimentario y actividad física en universitarios de tres carreras respecto a las guías alimentarias para la población argentina

RESUMEN Numerosos estudios coinciden en que el inicio de la vida universitaria se asocia a cambios poco saludables en prácticas alimentarias y estilos de vida que pueden consolidarse en la edad adulta. El objetivo fue valorar en qué medida estudiantes de tres carreras cumplen con las recomendaciones de las nuevas Guías Alimentarias para la Población Argentina de 2016. Se encuestaron 164 alumnos de Bioquímica (BQ), Licenciatura en Nutrición (LN) y Licenciatura en Biotecnología (LB) de la Universidad Nacional del Litoral. Los alumnos de LN se acercaron más a las recomendaciones que BQ y LB: mayor porcentaje realizaba cuatro comidas (45,0% vs 22,4% LB y 21,8% BQ, p= 0,009) y consumía diariamente leche/yogur (p= 0,042); los estudiantes de BQ presentaron el menor consumo de frutas (p= 0,000), mientras los de LB presentaron la menor ingesta de verduras (p= 0,023). El 79,3% del total realizaba actividad física y de ellos 59,8% alcanzó los 30 minutos diarios recomendados. La Universidad ofrece espacios de alimentación saludable (comedor universitario) y actividad física (predio de deportes) que no resultaban suficientemente aprovechados. Se concluye que resulta necesario planificar intervenciones para fomentar y/o mejorar patrones, consumo de alimentos y actividad física acordes a estilos más saludables en estos universitarios.

ABSTRACT Numerous studies agree that the beginning of university life is associated with unhealthy changes in eating practices and lifestyles that can be consolidated in adulthood. The aim of this study was to assess the extent to which the nutrition and physical activity of university students from three career programs comply with the recommendations of the new Dietary Guidelines for the Argentine Population (2016). One hundred and sixty-four (164) students of Biochemistry (BQ), Bachelor of Nutrition (LN) and Bachelor of Biotechnology (LB) of the Universidad Nacional del Litoral were surveyed. LN students approached the recommendations more than BQ and LB students: a higher percentage had four meals per day (45.0% LN vs. 22.4% LB and 21.8% BQ, p-value= 0.009) and consumed a daily portion of milk/yogurt (p-value= 0.042); the BQ students had the lowest fruit consumption (p-value= 0.000), while the LB students had the lowest vegetable intake (p-value= 0.023). All students presented patterns of intake and consumption of foods strongly influenced by the Argentine culture. Almost eighty percent (79.3%) of students did physical activity, but only 59.8% reached the recommended 30 minutes a day. The University offers healthy eating spaces (university canteen) and physical activity (sports grounds) that were not sufficiently exploited. It is concluded that it is necessary to plan interventions to promote and / or improve patterns of food consumption and physical activity, according to healthier lifestyles for university students.

CONOCIMIENTO Y PRÁCTICA DE RECOMENDACIONES SOBRE ALIMENTACIÓN SALUDABLE EN ESTUDIANTES UNIVERSITARIOS / KNOWLEDGE AND PRACTICE OF RECOMMENDATIONS ON HEALTHY FOOD IN UNIVERSITY STUDENTS

En la actualidad resulta evidente la relación que existe entre la alimentación y la salud. La etapa universitaria es un momento clave en la autonomía en la cual los jóvenes adquieren hábitos alimentarios propios, guiados en mayor o menor medida por gustos personales, influencias del entorno, factores económicos y la búsqueda de la salud, entre otros aspectos.

Imaging of Hydatid Disease with a Focus on Extrahepatic Involvement.

Hydatid disease (HD) is a parasitic infection caused by the larvae of a tapeworm that is endemic to many regions around the world-South America, Africa, and Asia, in particular. Humans are infected as intermediate hosts in the parasite's life cycle; thus, HD can be seen in persons living in areas where animal husbandry is practiced. However, owing to the varied patterns of migration and immigration during the past several decades, HD can be diagnosed in individuals living anywhere. The liver is the most common organ involved, with hepatic HD accounting for the majority of published cases. However, HD can affect multiple organs and tissues other than the liver, including the spleen, kidneys, lungs, heart, peritoneum, muscles, and brain. Knowledge of the route of spread, clinical findings at presentation, and possible complications involving each extrahepatic location can be useful for the radiologist when evaluating imaging findings in patients suspected of having HD. The ultrasonographic, computed tomographic, and magnetic resonance imaging findings of extrahepatic hydatid lesions frequently simulate those of hepatic HD, as long as rupture, bleeding, and/or superimposed bacterial infection has not occurred. Specific features of HD seen at different extrahepatic sites can help tailor the diagnosis. The differential diagnoses that can mimic HD at every nonhepatic location should be considered, as many of these entities are common, especially in nonendemic areas. ©RSNA, 2017.

Multimodality Imaging of Liver Infections: Differential Diagnosis and Potential Pitfalls.

Imaging plays an important role in the diagnosis, characterization, and management of infectious liver disease. In clinical practice, the main contributions of imaging are in detecting early disease, excluding other entities with a similar presentation, establishing a definitive diagnosis when classic findings are present, and guiding appropriate antimicrobial, interventional, or surgical treatment. The most common imaging features of bacterial, viral, parasitic, and fungal hepatic infections are described, and key imaging and clinical manifestations are reviewed that may be useful to narrow the differential diagnosis and avoid pitfalls in image interpretation. Ultrasonography (US), computed tomography (CT), and magnetic resonance imaging allow accurate detection of most hepatic infections and, in some circumstances, may provide specific signs to identify the underlying pathogen and exclude other entities with similar imaging features. In bacterial and parasitic infections, specific imaging features may be enough to exclude a neoplasm and, occasionally, to identify the underlying infectious agent. US and CT are important means to guide percutaneous aspiration or drainage when needed. In viral infections, imaging is critical to exclude entities that may manifest with similar clinical and laboratory findings. Disseminated fungal infections require early detection at imaging because they can be fatal if not promptly treated. Familiarity with the epidemiology, pathogenesis, clinical manifestations, imaging features, and treatment of hepatic infections can aid in radiologic diagnosis and guide appropriate patient care. (©)RSNA, 2016.

Reacciones desencadenadas por el embarazo en adolescentes e influencia del acompañamiento de la pareja a los controles prenatales, Hospital Germán Urquidi, segundo trimestre del 2011 / Reactions triggered by teen pregnancy and influence of the accompanying partner to prenatal checkups, Urquidi Germain Hospital, second quarter of 2011

La adolescencia es una etapa crucial en el desarrollo de las personas por los cambios físicos, psicológicos y sociales a los que se enfrentan, si estos cambios se ven afectados por un embarazo durante la adolescencia, las repercusiones pueden ser muy negativas para la mujer, su bebé y su entorno, por esta razón es importante el apoyo y acompañamiento que reciba la gestante adolescente, pues esto contribuirá a un mayor afrontamiento del embarazo y a reducir los riesgos que implica, siendo la participación de la pareja muy importante en este proceso.La investigación que se realizó tiene dos enfoques: cualitativo, porque tiene la finalidad de conocer las influencias psicológicas del acompañamiento de la pareja durante el control prenatal; cuantitativo porque se muestra estadísticamente las razones por las cuales la pareja no asiste al control prenatal. La investigación es de tipo descriptivo porque se estudian las influencias psicológicas del acompañamiento, transversal porque el estudio se realizó el segundo trimestre del 2011, prospectivo porque se registró la información según van ocurriendo los fenómenos sujetos a estudio.Los resultados reflejan que el 50 % de las adolescentes asisten solas al Control Prenatal y se sienten “tristes” y “deprimidas”, solo 23% recibe apoyo y acompañamiento de la pareja lo que repercute posteriormente en su estado de ánimo