1.
Bull Exp Biol Med
; 146(5): 658-61, 2008 Nov.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19526116
RESUMEN
A model of osteochondral intra-articular defect in rats is presented. During spontaneous healing, the stage of formation of granulation tissue is followed by its replacement with bone and fibrous tissue. Chondroinductive properties of collagen 1 sponge used for defect filling manifested in the formation of fibrous cartilage with fields of hyaline cartilage. Filling of the defect with collagen 1 sponge containing bone powder stimulated regeneration of the bone tissue and hyaline cartilage.